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Ajovy is a FDA approved, humanized monoclonal antibody (mAb) which selectively binds the calcitonin gene-related peptide (CGRP). It is being investigated for the prevention of migraine in adult Chinese patients.


Lead Product(s): Fremanezumab

Therapeutic Area: Neurology Product Name: Ajovy

Highest Development Status: ApprovedProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 11, 2024

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mAbxience will leverage its expertise in biosimilar development to develop and produce the biosimilar product currently in development for the treatment of multiple oncology indications.


Lead Product(s): Undisclosed

Therapeutic Area: Oncology Product Name: Undisclosed

Highest Development Status: UndisclosedProduct Type: Undisclosed

Recipient: Mabxience

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement April 04, 2024

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The collaboration aims to further accelerate the clinical research program of Teva’s ICS-SABA (TEV-56248), albuterol/fluticasone combination, currently in Phase 3 clinical trials for patients with asthma.


Lead Product(s): Fluticasone Propionate,Salbutamol Sulphate

Therapeutic Area: Pulmonary/Respiratory Diseases Product Name: TEV-56248

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Launch Therapeutics

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Collaboration April 01, 2024

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The net proceeds will be used to further accelerate the clinical research program of Teva’s ICS-SABA (TEV-56248), albuterol/fluticasone combination, currently in Phase 3 clinical trials for patients with asthma.


Lead Product(s): Fluticasone Propionate,Salbutamol Sulphate

Therapeutic Area: Pulmonary/Respiratory Diseases Product Name: TEV-56248

Highest Development Status: Phase IProduct Type: Small molecule

Partner/Sponsor/Collaborator: Abingworth

Deal Size: $150.0 million Upfront Cash: Undisclosed

Deal Type: Financing April 01, 2024

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Under the agreement, Teva will use Closed Loop Medicine’s proprietary SaMD platform which advances the development of personalised medicines, including CLM-HT01 (amlodipine), in patients with chronic disorders by combining dose-optimised drug therapy with digital care.


Lead Product(s): Amlodipine

Therapeutic Area: Cardiology/Vascular Diseases Product Name: CLM-HT01

Highest Development Status: UndisclosedProduct Type: Small molecule

Recipient: Closed Loop Medicine

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Partnership March 26, 2024

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The partnership aims to focus on the commercialization of Teva’s Austedo (deutetrabenazine). It is approved by the U.S. FDA in adults for the treatment of tardive dyskinesia and for the chorea associated with Huntington’s disease.


Lead Product(s): Deutetrabenazine

Therapeutic Area: Genetic Disease Product Name: Austedo

Highest Development Status: ApprovedProduct Type: Small molecule

Recipient: Jiangsu Nhwa Pharmaceutical

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Partnership February 26, 2024

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Simlandi (adalimumab) is the first interchangeable, high-concentration, citrate-free biosimilar to Humira approved for the treatment of adult rheumatoid arthritis, juvenile idiopathic arthritis, adult psoriatic arthritis, adult ankylosing spondylitis and Crohn’s disease.


Lead Product(s): Adalimumab

Therapeutic Area: Immunology Product Name: Simlandi

Highest Development Status: ApprovedProduct Type: Large molecule

Recipient: Alvotech

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 23, 2024

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TEV-44749 (olanzapine) is a novel D2/5-HT2 receptor inhibitor which is under phase 3 clinical development for the treatment of patients with Schizophrenia.


Lead Product(s): Olanzapine

Therapeutic Area: Psychiatry/Psychology Product Name: TEV-44749

Highest Development Status: Phase IIIProduct Type: Small molecule

Recipient: MedinCell

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 09, 2024

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Under the acquisition, Essential Pharma has acquired the rights to Colobreathe (colistimethate sodium), indicated for the management of chronic pulmonary infections due to Pseudomonas aeruginosa (PsA) in patients with cystic fibrosis, across European markets.


Lead Product(s): Colistimethate Sodium

Therapeutic Area: Infections and Infectious Diseases Product Name: Colobreathe

Highest Development Status: ApprovedProduct Type: Small molecule

Partner/Sponsor/Collaborator: Essential Pharma

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Acquisition January 08, 2024

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Under the agreement, Teva will receive exclusive rights to develop, manufacture and commercialize a potential novel antibody-based therapy, BD9, a dual specific antibody that can block both TSLP and IL-13, for the treatment of Atopic Dermatitis and Asthma.


Lead Product(s): BD9

Therapeutic Area: Dermatology Product Name: BD9

Highest Development Status: PreclinicalProduct Type: Large molecule

Recipient: Biolojic Design

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Licensing Agreement December 14, 2023

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