Blister packaging is todays most popular and growing packaging option worldwide, driven by its unique ability to provide Increased medicine protection, improved patient compliance and precise dose accuracy.
Contract blister packaging of drug products replaced bottles during this rebuilding phase. Today, the majority of prescription drug products are blister packaged for retail in Europe, while the majority of retail prescription drugs in the U.S. are supplied in bulk bottles.
Clinical trial drug supplies (solid oral doses) have historically been packaged in bottles rather than in blisters. First, of blister packaging costs more per unit dose than bottle packaging, primarily due to the small packaging runs needed to produce product for several hundred patients. Second, the time in which to complete the entire process was longer in duration with blister packaging due to the acquisition of blister tooling and the associated film and foil supplies. The majority of blister tooling for commercial equipment can average from six to sixteen weeks to complete and qualify. This additional project time was a significant disadvantage due to the short lead times associated with supplying clinical trial materials for patient evaluation. Third, most companies have a large investment in bottle filling equipment and few have blister packaging equipment for clinical trial supplies.
Pharma packaging companies provides smart source for complete pharmaceutical packagings, which are widely used for clinical trials, drugs promotion, as well as commercial packaging. As secondary packaging for pharmaceutical drugs, tablets and pills that are pre-packed in a primary blister/aluminium foil combination, your product can be easily pushed through, out of the blister strip for use, but with clearly visible and complete assurance that no tampering has occurred.
A wide variety of blister film materials and blister foil materials are available to choose from for pharmaceutical clinical packaging. Forming film choices include but are not limited to PVC, polypropylene, several coating grades of PVC/PVDC, and PVC/Aclar. A wide range of foils can be used to provide push through and/or peel/push product dispensing. More recently, cold form aluminum blister formats are being used to provide maximum product protection. This package format uses a formable foil to create the blister cavity and a foil lidding to seal the package.
The blister packaging machine or blistering equipment can deal with a variety of product sizes in either cold form or thermoform blister configurations. The machine can produce an all-aluminum blister package for products where moisture and light permeability must be kept to a minimum. Where a clear package is desired, the machine can quickly be changed over to produce a thermoform blister package using a high moisture barrier PVC/ACLAR® film structure or other plastic films to achieve the desired look and protective properties.
Pharmaceutical wallets and blister cards also offer the possibility to employ child resistant features and apply suitable warning labels. Blister packaging companies offers other packaging options that may be of interest in the pharmaceutical domain, such as a blister card which can dispense your product and then be reclosed for future use. The advantage of using clinical wallets in combination with a blister strip with tablets is that the information, printed on the wallet, always stays with the drugs itself unlike the case of folding boxes where the information about the drug is often lost after separating the blister strip from the box. Blister wallets make it easy to apply various options such as child-resistance, electronics, additional booklets etc.. Cold seal blister wallets have the benefit of an extremely simple and reliable sealing process. Only one parameter is required to get a perfect sealed package and that is pressure. Cold seal blister wallets are used globally by many customers such as Sanofi Aventis, Cipla, Ranbaxy, Dr. Reddies lab, Glenmark etc. Heat seal blister wallets require pressure and time and heat for sealing.
There are various blister packaging formats for blistering of tablet, blistering of capsule, blistering of softgel capsule range from standard PVC and foil combinations to high barrier laminates, as well as aluminium and aluminium blister packaging. Turnkey services include package design, foil printing, in-house tooling design and fabrication, high-speed blister packaging, serialization, custom designs and converting.
Various blister packaging services are Patient packs, Hospital unit dose packs, Child-resistant lidding, Multiple products per blister, Thermo-form and cold-form blisters, Polymer laminates (Aclar, PVC/PVDC, etc.), Online printing and pre-printed foil, Industry renowned IMA, Noack and Uhlmann blister lines, Serialisation at 5 levels: blister cavity, blister, carton, shipper and pallet.
Pharmaceutical blistering services or blistering services by blister packaging companies offers wide rage of blister designs having various options like custom blistering, semi-custom blistering. There are two types of sealing of blisters, heat sealing in which Heat and pressure are used to weld plastic blisters onto heat-activated adhesive coated cards. Typically used for face and trapped blisters. FCP has several Blister test method or blister package testing to measure the strength of heat seals to ensure quality seals, other one is cold sealing Solely utilizes pressure to make a seal. Typically used for sealing trapped blister packages, leveraging a cold-seal coating on the card. A simple, fast, cost-effective and environmentally-friendly method for sealing. Materials used for blister packaging are RPET Recycled Polyethylene Terephthalate is reclaimed post-consumer PET bottles and thermoforms recycled into new material to make new thermoform packaging, other one is PVC Polyvinyl Chloride is a thermoplastic resin or synthetic plastic polymer that comes in two basic forms: rigid and flexible.