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Find Drugs for Infections and Infectious Diseases in Phase I Clinical Development
Details :
PRV-101 is an investigational polyvalent vaccine being developed for the prevention of acute coxsackievirus B (CVB) infection and the potential delay or prevention of type 1 diabetes (T1D) and celiac disease.
Details :
Sanofi and Translate Bio have developed and will evaluate two formulations of the vaccine (MRT5400 and MRT5401) in the Phase 1 influenza mRNA vaccine clinical trial. The two formulations differ in the lipid nanoparticle (LNP) that contains the mRNA.
Details :
Sanofi and Translate Bio have developed and will evaluate two formulations of the vaccine (MRT5400 and MRT5401) in the Phase 1 influenza mRNA vaccine clinical trial. The two formulations differ in the lipid nanoparticle (LNP) that contains the mRNA.
Details :
The PRV-101 vaccine is specifically designed to prevent autoimmunity by primary prevention of a putative infectious trigger. Provention is developing PRV-101 for the prevention of acute CVB infection and the potential delay or prevention of type 1 diabet...
Details :
Dosing of DNL758 has commenced in a randomized, double-blind, placebo-controlled Phase 1b trial to evaluate safety and effect on the immune system in severe COVID-19.
Details :
CDI-988, a novel, oral, broad-spectrum 3CL protease inhibitor, receives HREC approval to conduct a Phase 1 study for the potential treatment for COVID-19.
Details :
The company will expand the clinical development of its lead asset BV100, a novel formulation of rifabutin being developed for hospital infections caused by Acinetobacter baumannii, in China.
Details :
NE3107 (bezisterim) is an orally bioavailable, BBB-permeable, insulin-sensitizer that is also anti-inflammatory. It is not immunosuppressive and has a low risk of drug-to-drug interaction.
Details :
The funding aims to support the clinical development of CVAX-01 to advance in the mid-stage clinical trial studies for treatment of patients related to Covid-19 infections.
Details :
OVX033 is a first-in-class coronavirus vaccine, targetting nucleocapsid (N), a highly conserved internal antigen, which is much less likely to mutate, providing a broader & universal immune response.
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