Solubilizer|Excipient|DDS|Tablet|Manufacturers

U.S.A

Advantose® 100 is a spray-dried maltose powder that provides excellent flow, solubility, and tableting properties to oral dosage forms. Maltose is well known for its safety and mouthfeel qualities, especially in chewable tablets and lozenges.

ADVANTOSE 100

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Ingredient(s): Maltose Sugar

Dosage Form: Tablet

Category: Solubilizers

Route of Administration (Grade): Oral

Pharmacopoeia Reference: NA

Technical Specifications: NA

CPHI North America

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Evonik Industries

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Germany

EUDRAGIT® L 100, a functional delayed release polymer for unique precise drug targeting, dissolution above pH 6.0 is often used to increases solubility of poorly soluble dosage forms such as tablets, capsules, ODTs, etc.

EUDRAGIT® L 100

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Ingredient(s): METHACRYLIC ACID COPOLYMER TYPE A

Dosage Form: Tablet

Category: Solubilizers

Route of Administration (Grade): Oral

Pharmacopoeia Reference: NA

Technical Specifications: Available as powder; Other grades- EUDRAGIT® L 12,5

Asia Pharmaceutics 2023

Not Confirmed

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Seqens

Seqens is an integrated global leader in pharmaceutical solutions & specialty ingredients, & custom-made solutions to our customers.

France

Vitamin E TPGS, a multirole excipient, act as surfactant which improves solubility of poorly water soluble drugs. It is also used in oral, nasal, ophthalmic, parenteral & topical applications.

VITAMIN E TPGS

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Ingredient(s): Vitamin E TPGS

Dosage Form: Tablet

Category: Solubilizers

Route of Administration (Grade): Oral, Topical

Pharmacopoeia Reference: GMO, BSE, TSE Certificates Available

Technical Specifications: Melting Point: 36-42 °C; Molecular weight: ~1.5 kDa; 25 % minimum weight basis; standard range 25-30 %

CPHI North America

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Gangwal Healthcare

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India

Complexol-HP® has mainly been used as complexing agent to increase aqueous solubility of poorly soluble drugs and to increase their bioavailability & stability. It can also be used to reduce gastrointestinal drug irritation.

COMPLEXOL HP

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Ingredient(s): Hydroxypropyl Betacyclodextrin

Dosage Form: Tablet

Category: Solubilizers

Route of Administration (Grade): Oral

Pharmacopoeia Reference: BP/EP/USP-NF

Technical Specifications: USDMF- 23816

Asia Pharmaceutics 2023

Not Confirmed

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Boai NKY Pharmaceuticals

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China

It is used as solubilizer and anti-crystallization agent in liquid dosage forms, matrix for amorphous solid dispersions via hot melt extrusion.

Digital Content

KOVIDONE® K12

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Ingredient(s): Polyvinylpyrrolidone

Dosage Form: Tablet

Category: Solubilizers

Route of Administration (Grade): Oral

Pharmacopoeia Reference: USP/NF, EP, JP, KP, IP, BP

Technical Specifications: NA

Asia Pharmaceutics 2023

Not Confirmed

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Evonik Industries

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Germany

EUDRAGIT® L 100-55 polymer is used in delayed and sustained release coatings to enhance solubility for poorly soluble drugs in solid oral dosage forms such as tablets, capsules, etc.

EUDRAGIT® L 100-55

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Ingredient(s): Methacrylic Acid - Ethyl Acrylate Copolymer

Dosage Form: Tablet

Category: Solubilizers

Route of Administration (Grade): Oral

Pharmacopoeia Reference: NA

Technical Specifications: Available as powder; Other grades- EUDRAGIT® L 30 D-55

Asia Pharmaceutics 2023

Not Confirmed

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Gangwal Healthcare

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India

Complexol B (Beta-Cyclodextrin) is used for molecular encapsulation of a variety of water insoluble or sparingly soluble compound to enhance stability, altering aqueous solubility and reduce volatility.

COMPLEXOL B

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Ingredient(s): Beta-Cyclodextrin

Dosage Form: Tablet

Category: Solubilizers

Route of Administration (Grade): Oral

Pharmacopoeia Reference: IP/BP/EP/USP-NF

Technical Specifications: Not Available

Asia Pharmaceutics 2023

Not Confirmed

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Evonik Industries

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Germany