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Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Obstetrics\/Gynecology (Women\u2019s Health)","country":"UNITED KINGDOM","productType":"Hormone","year":"2021","type":"Inapplicable","leadProduct":"Estradiol Valerate","moa":"Estrogen-alpha receptor","graph1":"Obstetrics\/Gynecology (Women\u2019s Health)","graph2":"Approved FDF","graph3":"Hikma Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Approved FDF","therapeuticAreaShortName":"Gynecology\/Obstetrics","amount2New":0,"dosageForm":"Injection","sponsorNew":"Hikma Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Hikma Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Intas Pharmaceuticals","sponsor":"Naari","pharmaFlowCategory":"D","therapeuticArea":"Obstetrics\/Gynecology (Women\u2019s 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Find Clinical Drug Development Pipelines & Deals | PipelineProspector

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                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : Inositol,Metformin

                          Therapeutic Area : Obstetrics/Gynecology (Women’s Health)

                          Study Phase : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Myo-Inositol is a sugar-alcohol compound that acts to regulate a number of hormones in the body, used for patients with Polycystic Ovarian Syndrome.

                          Product Name : Meno-D

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          August 09, 2022

                          Lead Product(s) : Inositol,Metformin

                          Therapeutic Area : Obstetrics/Gynecology (Women’s Health)

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Company Banner

                          02

                          Details : Alora® (Estradiol transdermal system) used for Treatment of Moderate to Severe Vasomotor Symptoms due to Menopause, Vulvar and Vaginal Atrophy due to Menopause, Hypoestrogenism Primary Ovarian Failure and Postmenopausal Osteoporosis.

                          Product Name : Alora

                          Product Type : Hormone

                          Upfront Cash : Undisclosed

                          March 16, 2021

                          Lead Product(s) : Estradiol

                          Therapeutic Area : Obstetrics/Gynecology (Women’s Health)

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Undisclosed

                          Deal Type : Divestment

                          Abbvie Company Banner

                          03

                          Details : Avion Pharmaceuticals gets exclusive rights to relaunch Cenestin® in the USA. Cenestin® is the only plant-derived mixture of nine conjugated estrogens indicated for treatment of moderate to severe symptoms of vasomotor, and vulvar and vaginal atrophy d...

                          Product Name : Cenestin

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          December 11, 2020

                          Lead Product(s) : Conjugated Estrogens

                          Therapeutic Area : Obstetrics/Gynecology (Women’s Health)

                          Highest Development Status : Approved FDF

                          Sponsor : Avion Pharmaceuticals

                          Deal Size : Undisclosed

                          Deal Type : Partnership

                          Aspen API Comapny Banner

                          04

                          Lead Product(s) : Progesterone

                          Therapeutic Area : Obstetrics/Gynecology (Women’s Health)

                          Study Phase : Approved FDF

                          Sponsor : Effik

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Enviero is first-of-its-kind, a green-chemistry progesterone that represents a step change in progesterone API synthesis, is manufactured via a proprietary biocatalytic process based on plant sterols that reduce waste, greenhouse gas emissions and use of...

                          Product Name : Estima

                          Product Type : Hormone

                          Upfront Cash : Inapplicable

                          November 18, 2020

                          Lead Product(s) : Progesterone

                          Therapeutic Area : Obstetrics/Gynecology (Women’s Health)

                          Highest Development Status : Approved FDF

                          Sponsor : Effik

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Pfizer centreOne

                          05

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Elinzanetant is the first NK-1 and NK-3 receptor dual antagonist and has demonstrated a significant mean reduction in the frequency and severity of moderate to severe VMS.

                          Product Name : Lynkuet

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          July 11, 2025

                          Lead Product(s) : Elinzanetant

                          Therapeutic Area : Obstetrics/Gynecology (Women’s Health)

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Under the licensing agreement, Windtree will hold the exclusive rights of Phexxi (lactic acid, citric acid, and potassium bitartrate) vaginal gel. It is being indicated to prevent prgenancy.

                          Product Name : Phexxi

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          March 20, 2025

                          Lead Product(s) : L-Lactic Acid,Lactic Acid,Potassium Bitartrate

                          Therapeutic Area : Obstetrics/Gynecology (Women’s Health)

                          Highest Development Status : Approved FDF

                          Sponsor : Windtree Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          07

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Through the acquisition, Cosette will utilize market-leading commercial products focused on women’s health, including Annovera (segesterone acetate & ethinyl estradiol) to prevent preganancy.

                          Product Name : Annovera

                          Product Type : Steroid

                          Upfront Cash : Undisclosed

                          February 20, 2025

                          Lead Product(s) : Segesterone Acetate,Ethinyl Estradiol

                          Therapeutic Area : Obstetrics/Gynecology (Women’s Health)

                          Highest Development Status : Approved FDF

                          Sponsor : Cosette Pharma

                          Deal Size : $430.0 million

                          Deal Type : Acquisition

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                          08

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Minzoya (levonorgestrel and ethinyl estradiol and ferrous bisglycinate Tablets) received approval from the US FDA, it is indicated for use by females of reproductive potential to prevent pregnancy.

                          Product Name : Minzoya

                          Product Type : Hormone

                          Upfront Cash : Inapplicable

                          January 13, 2025

                          Lead Product(s) : Levonorgestrel,Ethinyl Estradiol,Ferrous Bisglycinate

                          Therapeutic Area : Obstetrics/Gynecology (Women’s Health)

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : Nextstellis is a novel combination medication comprising of drospirenone (DRSP) and estetrol (E4), indicated for use by women of reproductive age to prevent pregnancy.

                          Product Name : Nextstellis

                          Product Type : Hormone

                          Upfront Cash : Undisclosed

                          December 06, 2024

                          Lead Product(s) : Drospirenone,Estetrol

                          Therapeutic Area : Obstetrics/Gynecology (Women’s Health)

                          Highest Development Status : Approved FDF

                          Sponsor : OLIC

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          10

                          EPSC
                          Not Confirmed
                          EPSC
                          Not Confirmed

                          Details : ANI launched Estradiol Gel, the generic equivalent of the reference listed drug (RLD), EstroGel for use after menopause to reduce moderate to severe hot flashes.

                          Product Name : Divigel-Generic

                          Product Type : Hormone

                          Upfront Cash : Inapplicable

                          October 25, 2024

                          Lead Product(s) : Estradiol

                          Therapeutic Area : Obstetrics/Gynecology (Women’s Health)

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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