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              Novo Nordisk

              • Development Update

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              DENMARK Denmark

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              In-Cosmetics Global

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              Novo Nordisk Reports Weight Loss of 14.9% (16.9% if taken as intended) in STEP 1 trial

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              Lead Product(s): Semaglutide

              Therapeutic Area: Nutrition and Weight Loss Product Name: Undisclosed

              Highest Development Status: Phase III Product Type: Large molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable June 04, 2020

              Details:

              People treated with sc semaglutide 2.4 mg achieved a weight loss of 14.9%, from a mean baseline body weight of 105.3 kg, compared to a 2.4% weight loss with placebo. Weight loss sustained after 68 weeks of treatment, compared to 31.5% with placebo.

              Novo Nordisk

              • Development Update

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              DENMARK Denmark

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              In-Cosmetics Global

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              Novo Nordisk’s First Semaglutide Obesity Trial Hits The Mark

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              Lead Product(s): Semaglutide

              Therapeutic Area: Nutrition and Weight Loss Product Name: Undisclosed

              Highest Development Status: Phase III Product Type: Large molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable May 13, 2020

              Details:

              Once-weekly semaglutide resulted in an average weight loss of 17.4% among people in a phase 3a trial, whereas those who received a dummy drug after a 20-week lead-in phase saw their body weight rebound by 6.9% during the rest 48 weeks.

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