Filter By Unselect All

Sub Category Unselect

Country Unselect See All

Companies Unselect See All

Selected Filter(s): Reset All

  • Category
  • Reset
  • Sub Category
  • Reset
  • Country
  • Reset

Contact

Mass Spectrometry & Electrospray Interfaces

Analytical >> Analytical Testing Services >> Mass spectrometry and LC / MS

Your GMP “One-Stop-Shop”, Angelini Fine Chemicals is a Contract Development and Manufacturing Organization (CDMO), which is fully dedicated to third party manufacturing of APIs, IMs and NCEs for the pharmaceutical and small molecule biotech industry.

Contact

Mass Spectrometry

Analytical >> Analytical Testing Services >> Mass spectrometry and LC / MS

Specializes in method development, validation & transfer, cGMP batch release testing, impurity characterization & identification, drug substance & product stability & comparability studies, protein/peptide crystallization & solid state characterization.

Contact

Chromatographic Techniques for NCEs & Peptide Analysis

Analytical >> Analytical Testing Services >> Mass spectrometry and LC / MS

Bachem is committed to using synthesis and purification strategies that yield products of the quality and purity you require. Our standard analytical package typically includes mass spectrometric analysis and determination of purity (by RP-HPLC).

Contact

Detection of Non-Chromophoric Molecules by LC-MS-Corona

Analytical >> Analytical Testing Services >> Mass spectrometry and LC / MS

Thanks to its innovative techniques (HPLC, SFC or combined preparative HPLC/SFC), DIVERCHIM proposes to its customers to isolate, purify and characterize process impurities as well as reference compounds.

Contact

Thermo Finnigan Surveyor MSQ Plus Mass Spectrometer

Analytical >> Analytical Testing Services >> Mass spectrometry and LC / MS

KriSan Biotech has dedicated analytical team that provides full analytical services for process development, GLP studies and CGMP manufacturing.

Contact

LC-MS/MS

Analytical >> Analytical Testing Services >> Mass spectrometry and LC / MS

Aizant's GLP certified bioanalytical laboratory is equipped with state-of-the art Liquid Chromatography and Tandem Mass Spectrometry (LC-MS/MS) instruments with a capacity of 4000 samples per week. We validate our analytical methods as per global regulatory requirements.

Contact

Identification of Degradant Products & Impurities (LC/MS)

Analytical >> Analytical Testing Services >> Mass spectrometry and LC / MS

Pharmavize operates an audited 1,600-m2 GMP facility serving clients from all over the world. We are thoroughly familiar with the European and American regulatory frameworks and guarantee compliance with all applicable guidelines and directives.

Contact

LC / MS, IR Techniques of Product Analysis

Analytical >> Analytical Testing Services >> Mass spectrometry and LC / MS

Acceleration Laboratory Services is the foremost Contract Solutions Provider for the pharmaceutical research. The ultimate goal for our associates is to deliver superior solutions to our clients, on time, and on point, while maintaining a fun and empowering work environment.

Contact

HPLC / MS / UV / GC

Analytical >> Analytical Testing Services >> Mass spectrometry and LC / MS

Crystec is an established pharmaceutical R&D company with the capacity to rapidly progress products from concept to clinical production. The company operates across three key sites (as listed below), and each incorporates characterisation and analytical suites which include - HPLC/MS/UV/GC

Contact

LC-MS-MS (Waters)

Analytical >> Analytical Testing Services >> Mass spectrometry and LC / MS

Neuland has a separate, specially equipped R&D Centre located at Bonthapally. Custom Synthesis is another area where Neuland has been concentrating and is taking up several projects. We work in close association with clients, under strict confidentiality, to bring products early to markets.

Mass spectrometry is a powerful analytical technique used to quantify known materials, to identify unknown compounds within a sample, and to elucidate the structure and chemical properties of different molecules. The complete process involves the conversion of the sample into gaseous ions, with or without fragmentation, which are then characterized by their mass to charge ratios (m/z) and relative abundances. This technique basically studies the effect of ionizing energy on molecules. It depends upon chemical reactions in the gas phase in which sample molecules are consumed during the formation of ionic and neutral species. The first step in the mass spectrometric analysis of compounds is the production of gas phase ions of the compound, basically by electron ionization. This molecular ion undergoes fragmentation. Each primary product ion derived from the molecular ion, in turn, undergoes fragmentation, and so on. The ions are separated in the mass spectrometer according to their mass-to-charge ratio, and are detected in proportion to their abundance. A mass spectrum of the molecule is thus produced. It displays the result in the form of a plot of ion abundance versus mass-to-charge ratio. Ions provide information concerning the nature and the structure of their precursor molecule. In the spectrum of a pure compound, the molecular ion, if present, appears at the highest value of m/z (followed by ions containing heavier isotopes) and gives the molecular mass of the compound. Mass spectrometry (MS) analysis of proteins measures the mass-to-charge ratio of ions to identify and quantify molecules in simple and complex mixtures. MS has become invaluable across a broad range of fields and applications, including proteomics. The development of high-throughput and quantitative MS proteomics workflows within the last two decades has expanded the scope of what we know about protein structure, function, modification and global protein dynamics. This overview outlines the role of mass spectrometry in the field of proteomics, reviews MS methodology and instrumentation, and touches on sample preparation and liquid chromatography–based separation prior to MS analysis.

ABOUT
THE PAGE

COLLAPSE

PharmaCompass >>