Drugs in Dev.
Hematology
Preclinical

Lead Product(s) : RLYB-331
Therapeutic Area : Hematology
Study Phase : Preclinical
Sponsor : Rallybio
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Rallybio plans to prosecute preclinical activities for KY1066/RLYB331 including CMC, and dose-range finding and toxicity studies, which will then support transition of the asset into clinical development.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : $3.0 million
May 10, 2022
Lead Product(s) : RLYB-331
Therapeutic Area : Hematology
Highest Development Status : Preclinical
Sponsor : Rallybio
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Iron
Therapeutic Area : Hematology
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lubrizol's Iron Shows Superior Absorption in Preclinical Study
Details : Iron, a vital mineral, targets hemoglobin to combat iron deficiency anemia (IDA) in patients.
Product Name : Lipofer
Product Type : Vitamins/Minerals/Inorganic Salts
Upfront Cash : Inapplicable
October 14, 2025
Lead Product(s) : Iron
Therapeutic Area : Hematology
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Losartan Potassium
Therapeutic Area : Hematology
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Kwality Pharma Gains on Securing RCGM Approval for Erythropoietin
Details : Kwality Pharmaceuticals gains RCGM approval for preclinical toxicity studies of recombinant Erythropoietin, advancing its biologics portfolio and targeting CKD-related anemia treatment.
Product Name : Undisclosed
Product Type : Hormone
Upfront Cash : Inapplicable
January 02, 2025
Lead Product(s) : Losartan Potassium
Therapeutic Area : Hematology
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : OKL-1111
Therapeutic Area : Hematology
Study Phase : Preclinical
Sponsor : Broadview Ventures
Deal Size : $5.2 million
Deal Type : Financing
Alveron Secures €5M Seed Extension Financing for Intracranial Hemorrhage Therapy
Details : The financing aims to advance the development of its innovative drug, OKL-1111, for the treatment of intracranial haemorrhage.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
December 06, 2024
Lead Product(s) : OKL-1111
Therapeutic Area : Hematology
Highest Development Status : Preclinical
Sponsor : Broadview Ventures
Deal Size : $5.2 million
Deal Type : Financing

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Lead Product(s) : Undisclosed
Therapeutic Area : Hematology
Study Phase : Preclinical
Sponsor : Bristol Myers Squibb
Deal Size : $3,610.0 million
Deal Type : Collaboration
BMS Pays Prime $110M to Form T-cell Therapy Pact
Details : Prime Medicine will design optimized Prime Editor reagents for a select number of targets, including reagents that use its Prime Assisted Site-Specific Integrase Gene Editing (PASSIGE™) technology.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : $110.0 million
September 30, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Hematology
Highest Development Status : Preclinical
Sponsor : Bristol Myers Squibb
Deal Size : $3,610.0 million
Deal Type : Collaboration

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Lead Product(s) : Undisclosed
Therapeutic Area : Hematology
Study Phase : Preclinical
Sponsor : Bristol Myers Squibb
Deal Size : $3,610.0 million
Deal Type : Collaboration
Prime Medicine and Bristol Myers Partner On Ex Vivo T-Cell Therapies
Details : The collaboration combines Prime Medicine’s precise, multiplex gene editing capabilities with BMS’s broad expertise in development and commercialization of novel ex vivo T-cell therapies.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
September 30, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Hematology
Highest Development Status : Preclinical
Sponsor : Bristol Myers Squibb
Deal Size : $3,610.0 million
Deal Type : Collaboration

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Lead Product(s) : PKM-02
Therapeutic Area : Hematology
Study Phase : Preclinical
Sponsor : Bpifrance
Deal Size : $1.6 million
Deal Type : Financing
PK MED Receives €1.5M DeepTech Financing from Bpifrance for Cell-Homing Implant
Details : The funding will accelerate the company’s PKM-02, an innovative technology aiming to enhance bone marrow transplantation in several diseases with high unmet medical need such as hemoglobinopathies.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
July 24, 2024
Lead Product(s) : PKM-02
Therapeutic Area : Hematology
Highest Development Status : Preclinical
Sponsor : Bpifrance
Deal Size : $1.6 million
Deal Type : Financing

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Lead Product(s) : Undisclosed
Therapeutic Area : Hematology
Study Phase : Preclinical
Sponsor : DanausGT Biotechnology
Deal Size : Undisclosed
Deal Type : Collaboration
Details : This collaboration will accelerate the development of innovative therapeutics for the treatment of some diseases such as blood, skin, and liver-related diseases.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
March 02, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Hematology
Highest Development Status : Preclinical
Sponsor : DanausGT Biotechnology
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : Undisclosed
Therapeutic Area : Hematology
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : $62.0 million
Deal Type : Series B Financing
Fly Like an Eagle: Garuda Brings in A $62M Series B
Details : The Series B funds will funnel into two programs Blood stem cell-based therapy, slated to hit the clinic in 2024 - transfusion-dependent beta-thalassemia (TDBT) in Europe and bone marrow failure syndrome in Europe, South America and North America
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
February 07, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Hematology
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : $62.0 million
Deal Type : Series B Financing

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Lead Product(s) : DISC-0998
Therapeutic Area : Hematology
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : DISC-0998 is an investigational anti-HJV mAb with an engineered Q and L mutation (QL-mutation) in the Fc region, aimed to alter binding to the FcRn receptor, resulting in an increased PK half-life.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
November 03, 2022
Lead Product(s) : DISC-0998
Therapeutic Area : Hematology
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable



