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    [{"orgOrder":0,"company":"Colgate Palmolive","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Dental and Oral Health","country":"INDIA","productType":"Vitamins\/Minerals\/Inorganic Salts","year":"2023","type":"Inapplicable","leadProduct":"L-Arginine","moa":"Cationic amino acid transporter 3; Antizyme inhibitor 2; Argininosuccinate lyase; Nitric oxide synthase, inducible; High affinity cationic amino acid transporter 1; Arginase-2, mitochondrial; Cationic amino acid transporter 4; Argininosuccinate synthase; Nitric oxide synthase 3","graph1":"Dental and Oral Health","graph2":"Phase I","graph3":"Colgate Palmolive","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Dental & Oral Health","amount2New":0,"dosageForm":"Paste","sponsorNew":"Colgate Palmolive \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Colgate Palmolive \/ Undisclosed"},{"orgOrder":0,"company":"Roya mohamed Hamad Elmaghrbi","sponsor":"Shofu Inc.","pharmaFlowCategory":"DU","therapeuticArea":"Dental and Oral Health","country":"","productType":"Miscellaneous","year":"2023","type":"Inapplicable","leadProduct":"Fluoride","moa":"Enamel","graph1":"Dental and Oral Health","graph2":"Phase I","graph3":"Roya mohamed Hamad Elmaghrbi","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Dental & Oral Health","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Roya mohamed Hamad Elmaghrbi \/ Shofu Inc.","highestDevelopmentStatusID":"6","companyTruncated":"Roya mohamed Hamad Elmaghrbi \/ Shofu Inc."},{"orgOrder":0,"company":"Protegera Inc","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Dental and Oral Health","country":"U.S.A","productType":"Miscellaneous","year":"2023","type":"Inapplicable","leadProduct":"Sodium Fluoride","moa":"Hydroxyapatite","graph1":"Dental and Oral Health","graph2":"Phase I","graph3":"Protegera Inc","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Dental & Oral Health","amount2New":0,"dosageForm":"Paste","sponsorNew":"Protegera Inc \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Protegera Inc \/ Undisclosed"},{"orgOrder":0,"company":"University of Oklahoma","sponsor":"Perio Protect","pharmaFlowCategory":"DU","therapeuticArea":"Dental and Oral Health","country":"U.S.A","productType":"Miscellaneous","year":"2023","type":"Inapplicable","leadProduct":"Hydrogen Peroxide","moa":"PTPN1 messenger RNA (PTPN1 mRNA)","graph1":"Dental and Oral Health","graph2":"Phase I","graph3":"University of Oklahoma","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Dental & Oral Health","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"University of Oklahoma \/ Perio Protect","highestDevelopmentStatusID":"6","companyTruncated":"University of Oklahoma \/ Perio Protect"},{"orgOrder":0,"company":"University of Santiago de Compostela","sponsor":"Lacer","pharmaFlowCategory":"DU","therapeuticArea":"Dental and Oral Health","country":"SPAIN","productType":"Miscellaneous","year":"2022","type":"Inapplicable","leadProduct":"Carvacrol","moa":"Undisclosed","graph1":"Dental and Oral Health","graph2":"Phase I","graph3":"University of Santiago de Compostela","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Dental & Oral Health","amount2New":0,"dosageForm":"Gargle\/Mouthwash","sponsorNew":"University of Santiago de Compostela \/ Lacer","highestDevelopmentStatusID":"6","companyTruncated":"University of Santiago de Compostela \/ Lacer"},{"orgOrder":0,"company":"Egymedicalpedia","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Dental and Oral Health","country":"","productType":"Undisclosed","year":"2023","type":"Inapplicable","leadProduct":"Egg Shell Nanoparticles","moa":"Undisclosed","graph1":"Dental and Oral Health","graph2":"Phase I","graph3":"Egymedicalpedia","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Dental & Oral Health","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Egymedicalpedia \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Egymedicalpedia \/ Undisclosed"},{"orgOrder":0,"company":"PROCTER AND GAMBLE","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Dental and Oral Health","country":"U.S.A","productType":"Undisclosed","year":"2024","type":"Inapplicable","leadProduct":"Mfp","moa":"Undisclosed","graph1":"Dental and Oral Health","graph2":"Phase I","graph3":"PROCTER AND GAMBLE","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Dental & Oral Health","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"PROCTER AND GAMBLE \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"PROCTER AND GAMBLE \/ Undisclosed"},{"orgOrder":0,"company":"Biolase","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Dental and Oral Health","country":"U.S.A","productType":"Dietary Supplement","year":"2022","type":"Inapplicable","leadProduct":"Perio Maint","moa":"Undisclosed","graph1":"Dental and Oral Health","graph2":"Phase I","graph3":"Biolase","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Dental & Oral Health","amount2New":0,"dosageForm":"Solution","sponsorNew":"Biolase \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Biolase \/ Undisclosed"},{"orgOrder":0,"company":"Egymedicalpedia","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Dental and Oral Health","country":"","productType":"Undisclosed","year":"2023","type":"Inapplicable","leadProduct":"Poly(Amidoamine) Dendrimer","moa":"Undisclosed","graph1":"Dental and Oral Health","graph2":"Phase I","graph3":"Egymedicalpedia","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Dental & Oral Health","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Egymedicalpedia \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Egymedicalpedia \/ Undisclosed"},{"orgOrder":0,"company":"Ostia Sciences","sponsor":"Natural Products Canada","pharmaFlowCategory":"D","therapeuticArea":"Dental and Oral Health","country":"U.S.A","productType":"Probiotic","year":"2025","type":"Financing","leadProduct":"SALI-10","moa":"Undisclosed","graph1":"Dental and Oral Health","graph2":"Phase I","graph3":"Ostia Sciences","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Dental & Oral Health","amount2New":0,"dosageForm":"Troche\/Lozenge","sponsorNew":"Ostia Sciences \/ Natural Products Canada","highestDevelopmentStatusID":"6","companyTruncated":"Ostia Sciences \/ Natural Products Canada"},{"orgOrder":0,"company":"PROCTER AND GAMBLE","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Dental and Oral Health","country":"U.S.A","productType":"Miscellaneous","year":"2025","type":"Inapplicable","leadProduct":"Fluorophosphate","moa":"Undisclosed","graph1":"Dental and Oral Health","graph2":"Phase I","graph3":"PROCTER AND GAMBLE","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Dental & Oral Health","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"PROCTER AND GAMBLE \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"PROCTER AND GAMBLE \/ Undisclosed"},{"orgOrder":0,"company":"Universidad de los Andes, Chile","sponsor":"Cells for Cells","pharmaFlowCategory":"DU","therapeuticArea":"Dental and Oral Health","country":"CHILE","productType":"Cell & Gene Therapy","year":"2022","type":"Inapplicable","leadProduct":"Umbilical Cord Derived Mesenchymal Stem Cell","moa":"Undisclosed","graph1":"Dental and Oral Health","graph2":"Phase I","graph3":"Universidad de los Andes, Chile","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Dental & Oral Health","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Universidad de los Andes, Chile \/ Cells for Cells","highestDevelopmentStatusID":"6","companyTruncated":"Universidad de los Andes, Chile \/ Cells for Cells"},{"orgOrder":0,"company":"Egymedicalpedia","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Dental and Oral Health","country":"","productType":"Undisclosed","year":"2022","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Dental and Oral Health","graph2":"Phase I","graph3":"Egymedicalpedia","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Dental & Oral Health","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Egymedicalpedia \/ Undisclosed","highestDevelopmentStatusID":"6","companyTruncated":"Egymedicalpedia \/ Undisclosed"}]

    Find Clinical Drug Development Pipelines & Deals | PipelineProspector

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                            01

                            Ostia Sciences

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                            Ostia Sciences

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                            Lead Product(s) : SALI-10

                            Therapeutic Area : Dental and Oral Health

                            Study Phase : Phase I

                            Sponsor : Natural Products Canada

                            Deal Size : $1.0 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Ostia Sciences Completes $1.46M Seed Round to Develop Microbiome Therapeutics Platform

                            Details : The funding supports the advancement of their phosphorylated lantibiotic-producing probiotic technology, particularly their lead candidate SALI-10, toward clinical trials for oral health.

                            Product Name : SALI-10

                            Product Type : Probiotic

                            Upfront Cash : Undisclosed

                            July 18, 2025

                            Lead Product(s) : SALI-10

                            Therapeutic Area : Dental and Oral Health

                            Highest Development Status : Phase I

                            Sponsor : Natural Products Canada

                            Deal Size : $1.0 million

                            Deal Type : Financing

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                            02

                            PROCTER AND GAMBLE

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                            The MedTech Conference
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                            PROCTER AND GAMBLE

                            U.S.A arrow
                            The MedTech Conference
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                            Lead Product(s) : Fluorophosphate

                            Therapeutic Area : Dental and Oral Health

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Evaluating Gingivitis and Systemic Biomarkers

                            Details : Sodium Monofluorophosphate is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Gingivitis.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            May 08, 2025

                            Lead Product(s) : Fluorophosphate

                            Therapeutic Area : Dental and Oral Health

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            PROCTER AND GAMBLE

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                            The MedTech Conference
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                            PROCTER AND GAMBLE

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                            Lead Product(s) : Mfp

                            Therapeutic Area : Dental and Oral Health

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Salivary Fluoride Clearance

                            Details : Mfp is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Dental Caries.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            December 16, 2024

                            Lead Product(s) : Mfp

                            Therapeutic Area : Dental and Oral Health

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Colgate Palmolive

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                            The MedTech Conference
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                            Colgate Palmolive

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                            Lead Product(s) : L-Arginine

                            Therapeutic Area : Dental and Oral Health

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Maximal Use Study to Determine the Pharmacokinetics of L-arginine After Exaggerated Oral Use of COL101

                            Details : L-Arginine is a Vitamins/Minerals/Inorganic Salts drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Dental Caries.

                            Product Name : Undisclosed

                            Product Type : Vitamins/Minerals/Inorganic Salts

                            Upfront Cash : Inapplicable

                            December 26, 2023

                            Lead Product(s) : L-Arginine

                            Therapeutic Area : Dental and Oral Health

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Protegera Inc

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                            The MedTech Conference
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                            Protegera Inc

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                            Lead Product(s) : Sodium Fluoride

                            Therapeutic Area : Dental and Oral Health

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Evaluation and Comparison of a Novel Dentrifice Formulation on Plaque Removal

                            Details : Sodium fluoride is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Dental Plaque.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            October 13, 2023

                            Lead Product(s) : Sodium Fluoride

                            Therapeutic Area : Dental and Oral Health

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Egymedicalpedia

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                            The MedTech Conference
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                            Egymedicalpedia

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                            Lead Product(s) : Egg Shell Nanoparticles

                            Therapeutic Area : Dental and Oral Health

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            The Effect of the Egg Shell Nanoparticles Combined With Titanium Dioxide Nanoparticles

                            Details : Egg Shell Nanoparticles is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Dentin Sensitivity.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            September 06, 2023

                            Lead Product(s) : Egg Shell Nanoparticles

                            Therapeutic Area : Dental and Oral Health

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Roya mohamed Hamad Elmaghrbi

                            Country arrow
                            The MedTech Conference
                            Not Confirmed

                            Roya mohamed Hamad Elmaghrbi

                            Country arrow
                            The MedTech Conference
                            Not Confirmed
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                            Lead Product(s) : Fluoride

                            Therapeutic Area : Dental and Oral Health

                            Study Phase : Phase I

                            Sponsor : Shofu Inc.

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Efficacy and Cost-effectiveness of Different Caries Preventive Protocols

                            Details : Fluoride is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Dental Caries.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            July 27, 2023

                            Lead Product(s) : Fluoride

                            Therapeutic Area : Dental and Oral Health

                            Highest Development Status : Phase I

                            Sponsor : Shofu Inc.

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Egymedicalpedia

                            Country arrow
                            The MedTech Conference
                            Not Confirmed

                            Egymedicalpedia

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                            The MedTech Conference
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                            Lead Product(s) : Poly(Amidoamine) Dendrimer

                            Therapeutic Area : Dental and Oral Health

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Effect of Poly Amido Amine Dendrimer, Nano-hydroxyapatite

                            Details : Poly(Amidoamine) Dendrimer is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Dental Caries.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            March 16, 2023

                            Lead Product(s) : Poly(Amidoamine) Dendrimer

                            Therapeutic Area : Dental and Oral Health

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            University of Oklahoma

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                            The MedTech Conference
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                            University of Oklahoma

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                            Lead Product(s) : Hydrogen Peroxide

                            Therapeutic Area : Dental and Oral Health

                            Study Phase : Phase I

                            Sponsor : Perio Protect

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Efficacy of Hydrogen Peroxide Gel on Periodontitis With Diabetes

                            Details : PerioProtect (Hydrogen Peroxide) is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Periodontitis.

                            Product Name : PerioProtect

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            January 03, 2023

                            Lead Product(s) : Hydrogen Peroxide

                            Therapeutic Area : Dental and Oral Health

                            Highest Development Status : Phase I

                            Sponsor : Perio Protect

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Egymedicalpedia

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                            Egymedicalpedia

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                            The MedTech Conference
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Dental and Oral Health

                            Study Phase : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Evaluation of the Effect of Self-Assembling Peptide P11-4

                            Details : This drug candidate is currently being evaluated in phase I clinical studies for the treatment of Dental Caries.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            December 28, 2022

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Dental and Oral Health

                            Highest Development Status : Phase I

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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