Drugs in Dev.
Dental and Oral Health
Phase I

Lead Product(s) : ColiSorB
Therapeutic Area : Dental and Oral Health
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : (ColiSorB) is currently being evaluated in Phase I clinical studies for the treatment of Molar Extraction Socket.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
September 18, 2025
Lead Product(s) : ColiSorB
Therapeutic Area : Dental and Oral Health
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : SALI-10
Therapeutic Area : Dental and Oral Health
Study Phase : Phase I
Sponsor : Natural Products Canada
Deal Size : $1.0 million
Deal Type : Financing
Ostia Sciences Completes $1.46M Seed Round to Develop Microbiome Therapeutics Platform
Details : The funding supports the advancement of their phosphorylated lantibiotic-producing probiotic technology, particularly their lead candidate SALI-10, toward clinical trials for oral health.
Product Name : SALI-10
Product Type : Probiotic
Upfront Cash : Undisclosed
July 18, 2025
Lead Product(s) : SALI-10
Therapeutic Area : Dental and Oral Health
Highest Development Status : Phase I
Sponsor : Natural Products Canada
Deal Size : $1.0 million
Deal Type : Financing

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Lead Product(s) : Fluorophosphate
Therapeutic Area : Dental and Oral Health
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Evaluating Gingivitis and Systemic Biomarkers
Details : Sodium Monofluorophosphate is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Gingivitis.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 08, 2025
Lead Product(s) : Fluorophosphate
Therapeutic Area : Dental and Oral Health
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Mfp
Therapeutic Area : Dental and Oral Health
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Mfp is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Dental Caries.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
December 16, 2024
Lead Product(s) : Mfp
Therapeutic Area : Dental and Oral Health
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : L-Arginine
Therapeutic Area : Dental and Oral Health
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : L-Arginine is a Vitamins/Minerals/Inorganic Salts drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Dental Caries.
Product Name : Undisclosed
Product Type : Vitamins/Minerals/Inorganic Salts
Upfront Cash : Inapplicable
December 26, 2023
Lead Product(s) : L-Arginine
Therapeutic Area : Dental and Oral Health
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Lead Product(s) : Sodium Fluoride
Therapeutic Area : Dental and Oral Health
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Evaluation and Comparison of a Novel Dentrifice Formulation on Plaque Removal
Details : Sodium fluoride is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Dental Plaque.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 13, 2023
Lead Product(s) : Sodium Fluoride
Therapeutic Area : Dental and Oral Health
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Lead Product(s) : Egg Shell Nanoparticles
Therapeutic Area : Dental and Oral Health
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
The Effect of the Egg Shell Nanoparticles Combined With Titanium Dioxide Nanoparticles
Details : Egg Shell Nanoparticles is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Dentin Sensitivity.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
September 06, 2023
Lead Product(s) : Egg Shell Nanoparticles
Therapeutic Area : Dental and Oral Health
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Lead Product(s) : Fluoride
Therapeutic Area : Dental and Oral Health
Study Phase : Phase I
Sponsor : Shofu Inc.
Deal Size : Inapplicable
Deal Type : Inapplicable
Efficacy and Cost-effectiveness of Different Caries Preventive Protocols
Details : Fluoride is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Dental Caries.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
July 27, 2023
Lead Product(s) : Fluoride
Therapeutic Area : Dental and Oral Health
Highest Development Status : Phase I
Sponsor : Shofu Inc.
Deal Size : Inapplicable
Deal Type : Inapplicable

Lead Product(s) : Poly(Amidoamine) Dendrimer
Therapeutic Area : Dental and Oral Health
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Effect of Poly Amido Amine Dendrimer, Nano-hydroxyapatite
Details : Poly(Amidoamine) Dendrimer is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Dental Caries.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
March 16, 2023
Lead Product(s) : Poly(Amidoamine) Dendrimer
Therapeutic Area : Dental and Oral Health
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

Lead Product(s) : Hydrogen Peroxide
Therapeutic Area : Dental and Oral Health
Study Phase : Phase I
Sponsor : Perio Protect
Deal Size : Inapplicable
Deal Type : Inapplicable
Efficacy of Hydrogen Peroxide Gel on Periodontitis With Diabetes
Details : PerioProtect (Hydrogen Peroxide) is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Periodontitis.
Product Name : PerioProtect
Product Type : Miscellaneous
Upfront Cash : Inapplicable
January 03, 2023
Lead Product(s) : Hydrogen Peroxide
Therapeutic Area : Dental and Oral Health
Highest Development Status : Phase I
Sponsor : Perio Protect
Deal Size : Inapplicable
Deal Type : Inapplicable
