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Find Clinical Drug Development Pipelines & Deals | PipelineProspector
Under the collaboration, Novo Nordisk will leverage Life Edit’s suite of gene editing technologies to precisely edit the genome with the aim of developing therapies for rare genetic disorders and cardiometabolic diseases allowing for the development of up to seven programmes.
The financing will be used to to support OMass as it continues to progress its pipeline of small molecule therapeutics for rare diseases and immunological conditions targeting solute carriers, complex-bound proteins and GPCRs.
CRADA combines Scenic Biotech’s genetic modifier platform with NIH’s patient registry to unlock genetic modifiers as a path to novel therapies for NPC disease. The goal of the collaboration is to obtain clinical insights into genes that can reduce the severity of NPC.
The collaboration will utilize GenKOre's proprietary CRISPR-Cas platform, TaRGET. The TaRGET platform is distinct from the most popular genome editing technology, CRISPR-Cas9, in that the whole editing module can be delivered with a single AAV vector.
ETH45 is a first-in-class inhalable form of Ethris’ proprietary mRNA for treatment of pulmonary alveolar proteinosis (PAP). ETH45 activates granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling in the presence of anti-GM-CF antibodies.
Through the collaboration, all members of POIC e dintorni and their parents will have access to whole genome sequencing. Genomic Biopharma’s GBI AI, uses predictive algorithms and genomic data mining to support the identification of novel RNA-based therapeutics.
The acquisition creates an opportunity to accelerate Alexion’s growth in genomic medicines through unique technology, an experienced rare disease R&D team, and expertise in pre-clinical development.
LogicBio's gene delivery platforms, coupled with Alexion’s advancements with AstraZeneca, will drive future scientific possibilities and next generation medicines to treat rare genetic diseases.
Under the terms of the agreement, KBio will have development rights to select assets within ZabBio’s current pipeline of antibody therapies – including a late-stage preclinical anti-fungal mAb – as well as future products discovered under the collaboration.
Lead Product(s):
Monoclonal Antibody-based Therapy
Proceeds from Series B will be used to expand Octant’s platform capabilities and pipeline, advance its proprietary drug discovery technology, and generate extensive datasets that map the relationships between drug candidates, genetics, and biochemical mechanism of human cells.
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