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Maturi, MD"},{"orgOrder":0,"company":"Novartis Pharmaceuticals Corporation","sponsor":"GWT-TUD","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"SWITZERLAND","productType":"Antibody, Unconjugated","year":"2014","type":"Inapplicable","leadProduct":"Ranibizumab","moa":"Vascular endothelial growth factor A","graph1":"Ophthalmology","graph2":"Phase IV","graph3":"Novartis Pharmaceuticals Corporation","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Novartis Pharmaceuticals Corporation \/ GWT-TUD","highestDevelopmentStatusID":"11","companyTruncated":"Novartis Pharmaceuticals Corporation \/ GWT-TUD"},{"orgOrder":0,"company":"Genentech","sponsor":"Charles C Wykoff","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2012","type":"Inapplicable","leadProduct":"Ranibizumab","moa":"Vascular endothelial growth factor A","graph1":"Ophthalmology","graph2":"Phase IV","graph3":"Genentech","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Genentech \/ Charles C Wykoff","highestDevelopmentStatusID":"11","companyTruncated":"Genentech \/ Charles C Wykoff"},{"orgOrder":0,"company":"Genentech","sponsor":"Peter A Campochiaro, MD","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2010","type":"Inapplicable","leadProduct":"Ranibizumab","moa":"Vascular endothelial growth factor A","graph1":"Ophthalmology","graph2":"Phase IV","graph3":"Genentech","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Genentech \/ Peter A Campochiaro, MD","highestDevelopmentStatusID":"11","companyTruncated":"Genentech \/ Peter A Campochiaro, MD"},{"orgOrder":0,"company":"Genentech","sponsor":"Anne Fung","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2010","type":"Inapplicable","leadProduct":"Ranibizumab","moa":"Vascular endothelial growth factor A","graph1":"Ophthalmology","graph2":"Phase IV","graph3":"Genentech","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Genentech \/ Anne Fung","highestDevelopmentStatusID":"11","companyTruncated":"Genentech \/ Anne Fung"},{"orgOrder":0,"company":"Genentech","sponsor":"Arshad Khanani","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2013","type":"Inapplicable","leadProduct":"Ranibizumab","moa":"Vascular endothelial growth factor A","graph1":"Ophthalmology","graph2":"Phase IV","graph3":"Genentech","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Genentech \/ Arshad Khanani","highestDevelopmentStatusID":"11","companyTruncated":"Genentech \/ Arshad Khanani"},{"orgOrder":0,"company":"Genentech","sponsor":"Thomas Hanscom","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2011","type":"Inapplicable","leadProduct":"Ranibizumab","moa":"Vascular endothelial growth factor A","graph1":"Ophthalmology","graph2":"Phase IV","graph3":"Genentech","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Genentech \/ Thomas Hanscom","highestDevelopmentStatusID":"11","companyTruncated":"Genentech \/ Thomas Hanscom"},{"orgOrder":0,"company":"Regeneron Pharmaceuticals","sponsor":"Gregg T. Kokame, MD","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Protein","year":"2013","type":"Inapplicable","leadProduct":"Aflibercept","moa":"Vascular endothelial growth factor A | Placenta growth factor","graph1":"Ophthalmology","graph2":"Phase IV","graph3":"Regeneron Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Regeneron Pharmaceuticals \/ Gregg T. Kokame, MD","highestDevelopmentStatusID":"11","companyTruncated":"Regeneron Pharmaceuticals \/ Gregg T. Kokame, MD"},{"orgOrder":0,"company":"Regeneron Pharmaceuticals","sponsor":"Justis Ehlers","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Protein","year":"2015","type":"Inapplicable","leadProduct":"Aflibercept","moa":"Vascular endothelial growth factor A | Placenta growth factor","graph1":"Ophthalmology","graph2":"Phase IV","graph3":"Regeneron Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Regeneron Pharmaceuticals \/ Justis Ehlers","highestDevelopmentStatusID":"11","companyTruncated":"Regeneron Pharmaceuticals \/ Justis Ehlers"},{"orgOrder":0,"company":"University of Miami","sponsor":"AbbVie Inc","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"HPAPI","year":"2025","type":"Inapplicable","leadProduct":"Bimatoprost","moa":"Prostanoid receptor","graph1":"Ophthalmology","graph2":"Phase IV","graph3":"University of Miami","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Implant","sponsorNew":"University of Miami \/ AbbVie Inc","highestDevelopmentStatusID":"11","companyTruncated":"University of Miami \/ AbbVie Inc"}]

Find Ophthalmology Drugs in Phase IV Development

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                          Top Deals by Deal Size (USD bn)

                          01

                          Details : Adalimumab is a Antibody drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Uveitis.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          June 10, 2022

                          Lead Product(s) : Adalimumab

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase IV

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Abbvie Company Banner

                          02

                          Details : Xalatan is a Other Small Molecule drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Glaucoma, Open-Angle.

                          Product Name : Undisclosed

                          Product Type : HPAPI

                          Upfront Cash : Inapplicable

                          June 08, 2016

                          Lead Product(s) : Latanoprost

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase IV

                          Sponsor : David Yan

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Abbvie Company Banner

                          03

                          Details : Bevacizumab is a Antibody drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Macular Edema.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          January 15, 2014

                          Lead Product(s) : Bevacizumab

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase IV

                          Sponsor : Raj K. Maturi, MD

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Abbvie Company Banner

                          04

                          Details : Alcaftadine is a Other Small Molecule drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Conjunctivitis, Allergic.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          July 11, 2011

                          Lead Product(s) : Alcaftadine

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase IV

                          Sponsor : Milton M. Hom

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Abbvie Company Banner

                          05

                          Details : HYDROXYPROPYLMETHYLCELLULOSE is a Other Small Molecule drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Dry Eye Syndromes.

                          Product Name : Undisclosed

                          Product Type : Carbohydrate

                          Upfront Cash : Inapplicable

                          October 25, 2010

                          Lead Product(s) : HYDROXYPROPYLMETHYLCELLULOSE

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase IV

                          Sponsor : Milton M. Hom

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Abbvie Company Banner

                          06

                          University of Miami

                          Country arrow
                          ISPE Annual Meeting
                          Not Confirmed

                          University of Miami

                          Country arrow
                          ISPE Annual Meeting
                          Not Confirmed

                          Details : Durysta (bimatoprost) is a HPAPI drug candidate, which is currently being evaluated in Phase IV clinical studies for the treatment of Glaucoma.

                          Product Name : Durysta

                          Product Type : HPAPI

                          Upfront Cash : Inapplicable

                          October 16, 2025

                          Lead Product(s) : Bimatoprost

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase IV

                          Sponsor : AbbVie Inc

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Insight Eyecare Specialties, Inc

                          Country arrow
                          ISPE Annual Meeting
                          Not Confirmed

                          Insight Eyecare Specialties, Inc

                          Country arrow
                          ISPE Annual Meeting
                          Not Confirmed

                          Details : Brimonidine Tartrate is a small molecule drug candidate, which is currently being evaluated in Phase IV clinical studies for the treatment of Glaucoma.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          October 07, 2025

                          Lead Product(s) : Brimonidine Tartrate

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase IV

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Ace Cells Lab

                          Country arrow
                          ISPE Annual Meeting
                          Not Confirmed

                          Ace Cells Lab

                          Country arrow
                          ISPE Annual Meeting
                          Not Confirmed

                          Details : This drug candidate is currently being evaluated in Phase IV clinical studies for the treatment of Dry Eye Syndromes.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          September 25, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase IV

                          Sponsor : University of Nottingham

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          ISPE Annual Meeting
                          Not Confirmed
                          ISPE Annual Meeting
                          Not Confirmed

                          Details : Perfluorohexyloctane is a Other Small Molecule drug candidate, which is currently being evaluated in Phase IV clinical studies for the treatment of Dry Eye Syndromes.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          July 08, 2025

                          Lead Product(s) : Perfluorohexyloctane

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase IV

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          Scripps Poway Eyecare and Optometry

                          Country arrow
                          ISPE Annual Meeting
                          Not Confirmed

                          Scripps Poway Eyecare and Optometry

                          Country arrow
                          ISPE Annual Meeting
                          Not Confirmed

                          Details : Systane PRO is a Other Small Molecule drug candidate, which is currently being evaluated in Phase IV clinical studies for the treatment of Dry Eye Syndromes.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          May 16, 2025

                          Lead Product(s) : Systane PRO

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase IV

                          Sponsor : Sengi

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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