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Maturi, MD"},{"orgOrder":0,"company":"Novartis Pharmaceuticals Corporation","sponsor":"GWT-TUD","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"SWITZERLAND","productType":"Antibody, Unconjugated","year":"2014","type":"Inapplicable","leadProduct":"Ranibizumab","moa":"Vascular endothelial growth factor A","graph1":"Ophthalmology","graph2":"Phase IV","graph3":"Novartis Pharmaceuticals Corporation","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Novartis Pharmaceuticals Corporation \/ GWT-TUD","highestDevelopmentStatusID":"11","companyTruncated":"Novartis Pharmaceuticals Corporation \/ GWT-TUD"},{"orgOrder":0,"company":"Genentech","sponsor":"Charles C Wykoff","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2012","type":"Inapplicable","leadProduct":"Ranibizumab","moa":"Vascular endothelial growth factor A","graph1":"Ophthalmology","graph2":"Phase IV","graph3":"Genentech","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Genentech \/ Charles C Wykoff","highestDevelopmentStatusID":"11","companyTruncated":"Genentech \/ Charles C Wykoff"},{"orgOrder":0,"company":"Genentech","sponsor":"Peter A Campochiaro, MD","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2010","type":"Inapplicable","leadProduct":"Ranibizumab","moa":"Vascular endothelial growth factor A","graph1":"Ophthalmology","graph2":"Phase IV","graph3":"Genentech","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Genentech \/ Peter A Campochiaro, MD","highestDevelopmentStatusID":"11","companyTruncated":"Genentech \/ Peter A Campochiaro, MD"},{"orgOrder":0,"company":"Genentech","sponsor":"Anne Fung","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2010","type":"Inapplicable","leadProduct":"Ranibizumab","moa":"Vascular endothelial growth factor A","graph1":"Ophthalmology","graph2":"Phase IV","graph3":"Genentech","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Genentech \/ Anne Fung","highestDevelopmentStatusID":"11","companyTruncated":"Genentech \/ Anne Fung"},{"orgOrder":0,"company":"Genentech","sponsor":"Arshad Khanani","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2013","type":"Inapplicable","leadProduct":"Ranibizumab","moa":"Vascular endothelial growth factor A","graph1":"Ophthalmology","graph2":"Phase IV","graph3":"Genentech","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Genentech \/ Arshad Khanani","highestDevelopmentStatusID":"11","companyTruncated":"Genentech \/ Arshad Khanani"},{"orgOrder":0,"company":"Genentech","sponsor":"Thomas Hanscom","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2011","type":"Inapplicable","leadProduct":"Ranibizumab","moa":"Vascular endothelial growth factor A","graph1":"Ophthalmology","graph2":"Phase IV","graph3":"Genentech","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Genentech \/ Thomas Hanscom","highestDevelopmentStatusID":"11","companyTruncated":"Genentech \/ Thomas Hanscom"},{"orgOrder":0,"company":"Regeneron Pharmaceuticals","sponsor":"Gregg T. Kokame, MD","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Protein","year":"2013","type":"Inapplicable","leadProduct":"Aflibercept","moa":"Vascular endothelial growth factor A | Placenta growth factor","graph1":"Ophthalmology","graph2":"Phase IV","graph3":"Regeneron Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Regeneron Pharmaceuticals \/ Gregg T. Kokame, MD","highestDevelopmentStatusID":"11","companyTruncated":"Regeneron Pharmaceuticals \/ Gregg T. Kokame, MD"},{"orgOrder":0,"company":"Regeneron Pharmaceuticals","sponsor":"Justis Ehlers","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"Protein","year":"2015","type":"Inapplicable","leadProduct":"Aflibercept","moa":"Vascular endothelial growth factor A | Placenta growth factor","graph1":"Ophthalmology","graph2":"Phase IV","graph3":"Regeneron Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Regeneron Pharmaceuticals \/ Justis Ehlers","highestDevelopmentStatusID":"11","companyTruncated":"Regeneron Pharmaceuticals \/ Justis Ehlers"},{"orgOrder":0,"company":"University of Miami","sponsor":"AbbVie Inc","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"U.S.A","productType":"HPAPI","year":"2025","type":"Inapplicable","leadProduct":"Bimatoprost","moa":"Prostanoid receptor","graph1":"Ophthalmology","graph2":"Phase IV","graph3":"University of Miami","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Implant","sponsorNew":"University of Miami \/ AbbVie Inc","highestDevelopmentStatusID":"11","companyTruncated":"University of Miami \/ AbbVie Inc"}]

    Find Ophthalmology Drugs in Phase IV Development

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                            01

                            AbbVie Inc

                            U.S.A
                            ISPE Annual Meeting
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Adalimumab

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase IV

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study to Assess Change in Disease Activity and Adverse Events of Adalimumab in Chinese Participants Requirin...

                            Details : Adalimumab is a Antibody drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Uveitis.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            June 10, 2022

                            Lead Product(s) : Adalimumab

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase IV

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            AbbVie Inc

                            U.S.A
                            ISPE Annual Meeting
                            Not Confirmed
                            • fda
                            • EDQM
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                            Lead Product(s) : Latanoprost

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase IV

                            Sponsor : David Yan

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Comparison of Xalatan (Latanoprost) to Apo-latanoprost and Co-latanoprost in the Treatment of Glaucoma

                            Details : Xalatan is a Other Small Molecule drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Glaucoma, Open-Angle.

                            Product Name : Undisclosed

                            Product Type : HPAPI

                            Upfront Cash : Inapplicable

                            June 08, 2016

                            Lead Product(s) : Latanoprost

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase IV

                            Sponsor : David Yan

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            AbbVie Inc

                            U.S.A
                            ISPE Annual Meeting
                            Not Confirmed
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                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Bevacizumab

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase IV

                            Sponsor : Raj K. Maturi, MD

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Anti-Vascular Endothelial Growth Factor (Anti-VEGF) Alone Versus Ozurdex Given Every 3 Months for Treatment of...

                            Details : Bevacizumab is a Antibody drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Macular Edema.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            January 15, 2014

                            Lead Product(s) : Bevacizumab

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase IV

                            Sponsor : Raj K. Maturi, MD

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            AbbVie Inc

                            U.S.A
                            ISPE Annual Meeting
                            Not Confirmed
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                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Alcaftadine

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase IV

                            Sponsor : Milton M. Hom

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Comparison of Tolerability Between Two Allergy Drops

                            Details : Alcaftadine is a Other Small Molecule drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Conjunctivitis, Allergic.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            July 11, 2011

                            Lead Product(s) : Alcaftadine

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase IV

                            Sponsor : Milton M. Hom

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            AbbVie Inc

                            U.S.A
                            ISPE Annual Meeting
                            Not Confirmed
                            • fda
                            • EDQM
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                            Lead Product(s) : HYDROXYPROPYLMETHYLCELLULOSE

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase IV

                            Sponsor : Milton M. Hom

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Tear Osmolarity Over Time With Artificial Tears

                            Details : HYDROXYPROPYLMETHYLCELLULOSE is a Other Small Molecule drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Dry Eye Syndromes.

                            Product Name : Undisclosed

                            Product Type : Carbohydrate

                            Upfront Cash : Inapplicable

                            October 25, 2010

                            Lead Product(s) : HYDROXYPROPYLMETHYLCELLULOSE

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase IV

                            Sponsor : Milton M. Hom

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            University of Miami

                            Country arrow
                            ISPE Annual Meeting
                            Not Confirmed

                            University of Miami

                            Country arrow
                            ISPE Annual Meeting
                            Not Confirmed
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                            Lead Product(s) : Bimatoprost

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase IV

                            Sponsor : AbbVie Inc

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Biomarkers of Ocular Surface Damage in the Setting of Topical Ocular Hypotensive Medication Use

                            Details : Durysta (bimatoprost) is a HPAPI drug candidate, which is currently being evaluated in Phase IV clinical studies for the treatment of Glaucoma.

                            Product Name : Durysta

                            Product Type : HPAPI

                            Upfront Cash : Inapplicable

                            October 16, 2025

                            Lead Product(s) : Bimatoprost

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase IV

                            Sponsor : AbbVie Inc

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Insight Eyecare Specialties, Inc

                            Country arrow
                            ISPE Annual Meeting
                            Not Confirmed

                            Insight Eyecare Specialties, Inc

                            Country arrow
                            ISPE Annual Meeting
                            Not Confirmed
                            • fda
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                            Lead Product(s) : Brimonidine Tartrate

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase IV

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Evaluating Injection With the Use of Brimonidine Tartrate Ophthalmic 0.025% on Patients Using Netarsudil 0.02%...

                            Details : Brimonidine Tartrate is a small molecule drug candidate, which is currently being evaluated in Phase IV clinical studies for the treatment of Glaucoma.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            October 07, 2025

                            Lead Product(s) : Brimonidine Tartrate

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase IV

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Ace Cells Lab

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                            ISPE Annual Meeting
                            Not Confirmed

                            Ace Cells Lab

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                            ISPE Annual Meeting
                            Not Confirmed
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase IV

                            Sponsor : University of Nottingham

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Assessment of CataClear, Tear Film Stability, Tear Volume, and Dry Eye Symptoms Using Stem Cells Fortified Eye...

                            Details : This drug candidate is currently being evaluated in Phase IV clinical studies for the treatment of Dry Eye Syndromes.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            September 25, 2025

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase IV

                            Sponsor : University of Nottingham

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Bausch & Lomb Incorporated

                            Canada arrow
                            ISPE Annual Meeting
                            Not Confirmed

                            Bausch & Lomb Incorporated

                            Canada arrow
                            ISPE Annual Meeting
                            Not Confirmed
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                            Lead Product(s) : Perfluorohexyloctane

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase IV

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study to Evaluate Concomitant Perfluorohexyloctane Use with Contact Lens Wear

                            Details : Perfluorohexyloctane is a Other Small Molecule drug candidate, which is currently being evaluated in Phase IV clinical studies for the treatment of Dry Eye Syndromes.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            July 08, 2025

                            Lead Product(s) : Perfluorohexyloctane

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase IV

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Scripps Poway Eyecare and Optometry

                            Country arrow
                            ISPE Annual Meeting
                            Not Confirmed

                            Scripps Poway Eyecare and Optometry

                            Country arrow
                            ISPE Annual Meeting
                            Not Confirmed
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                            Lead Product(s) : Systane PRO

                            Therapeutic Area : Ophthalmology

                            Study Phase : Phase IV

                            Sponsor : Sengi

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Performance of Systane PRO Versus Refresh Optive Mega-3

                            Details : Systane PRO is a Other Small Molecule drug candidate, which is currently being evaluated in Phase IV clinical studies for the treatment of Dry Eye Syndromes.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            May 16, 2025

                            Lead Product(s) : Systane PRO

                            Therapeutic Area : Ophthalmology

                            Highest Development Status : Phase IV

                            Sponsor : Sengi

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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