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Laser Raman spectroscopy depends on a change in the polarization of a molecule to produce Raman scattering. When a beam of photons strikes a molecule, the photons are scattered elastically (Rayleigh scattering) and inelastically (Raman scattering) generating Stoke’s and anti-Stokes lines. Because Raman spectroscopy is a scattering process, samples of any size or shape can be examined. Very small amounts of material can be studied down to microscopic levels (~1µm). Surface-enhanced Raman spectros