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    [{"orgOrder":0,"company":"NanoSurface Biomedical","sponsor":"National Institutes of Health","pharmaFlowCategory":"D","therapeuticArea":"Pharmacology\/Toxicology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2020","type":"Funding","leadProduct":"Human Ipsc-Derived Cardiac Tissues","moa":"Undisclosed","graph1":"Pharmacology\/Toxicology","graph2":"Preclinical","graph3":"NanoSurface Biomedical","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Toxicology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"NanoSurface Biomedical \/ National Institutes of Health","highestDevelopmentStatusID":"4","companyTruncated":"NanoSurface Biomedical \/ National Institutes of Health"},{"orgOrder":0,"company":"Incyte Corporation","sponsor":"Novartis Pharmaceuticals Corporation","pharmaFlowCategory":"D","therapeuticArea":"Pharmacology\/Toxicology","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Collaboration","leadProduct":"Ruxolitinib Phosphate","moa":"JAK1\/JAK2","graph1":"Pharmacology\/Toxicology","graph2":"Preclinical","graph3":"Incyte Corporation","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Toxicology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Incyte Corporation \/ Novartis Pharmaceuticals Corporation","highestDevelopmentStatusID":"4","companyTruncated":"Incyte Corporation \/ Novartis Pharmaceuticals Corporation"},{"orgOrder":0,"company":"The Wistar Institute","sponsor":"Jubilant Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Pharmacology\/Toxicology","country":"U.S.A","productType":"Undisclosed","year":"2021","type":"Collaboration","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Pharmacology\/Toxicology","graph2":"Preclinical","graph3":"The Wistar Institute","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Toxicology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"The Wistar Institute \/ Jubilant Therapeutics","highestDevelopmentStatusID":"4","companyTruncated":"The Wistar Institute \/ Jubilant Therapeutics"},{"orgOrder":0,"company":"RedHill Biopharma","sponsor":"Duke University School of Medicine","pharmaFlowCategory":"D","therapeuticArea":"Pharmacology\/Toxicology","country":"ISRAEL","productType":"Other Small Molecule","year":"2024","type":"Collaboration","leadProduct":"Opaganib","moa":"SPHK2","graph1":"Pharmacology\/Toxicology","graph2":"Preclinical","graph3":"RedHill Biopharma","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Toxicology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"RedHill Biopharma \/ Duke University School of Medicine","highestDevelopmentStatusID":"4","companyTruncated":"RedHill Biopharma \/ Duke University School of Medicine"}]

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                            01

                            RedHill Biopharma

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                            RedHill Biopharma

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                            Lead Product(s) : Opaganib

                            Therapeutic Area : Pharmacology/Toxicology

                            Study Phase : Preclinical

                            Sponsor : Duke University School of Medicine

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            RedHill Collaborates with U.S. Academic Center on Opaganib for Phosgene Injury

                            Details : The collaboration is designed to test ABC294640 (opaganib), a first-in-class, orally administered SPHK2 selective inhibitor, as a potential medical countermeasure to treat phosgene inhalation injury.

                            Product Name : Yeliva

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            October 22, 2024

                            Lead Product(s) : Opaganib

                            Therapeutic Area : Pharmacology/Toxicology

                            Highest Development Status : Preclinical

                            Sponsor : Duke University School of Medicine

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            02

                            Amryt Pharma

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                            Lead Product(s) : Octreotide Acetate

                            Therapeutic Area : Pharmacology/Toxicology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Amryt Receives Orphan Drug Designation from the FDA for Mycapssa (Oral Octreotide) for the Treatment of Carcin...

                            Details : Mycapssa® (octreotide capsules) is approved in the US for long-term maintenance therapy in acromegaly patients who have responded to and tolerated treatment with octreotide or lanreotide. Mycapssa® is the first and only oral somatostatin analog approve...

                            Product Name : Mycapssa

                            Product Type : Peptide

                            Upfront Cash : Inapplicable

                            July 14, 2022

                            Lead Product(s) : Octreotide Acetate

                            Therapeutic Area : Pharmacology/Toxicology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            The Wistar Institute

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Pharmacology/Toxicology

                            Study Phase : Preclinical

                            Sponsor : Jubilant Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            Jubilant Therapeutics Announces Research Collaboration with The Wistar Institute to Evaluate the Activity of N...

                            Details : Collaboration aims to evaluate the ability of Peptidyl Arginine Deiminase 4 (PAD4) inhibitors provided by Jubilant Therapeutics to block neutrophil extracellular trap (NET) formation in the context of COVID-19 related cytokine storms.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            January 15, 2021

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Pharmacology/Toxicology

                            Highest Development Status : Preclinical

                            Sponsor : Jubilant Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            04

                            NanoSurface Biomedical

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                            NanoSurface Biomedical

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                            Lead Product(s) : Human Ipsc-Derived Cardiac Tissues

                            Therapeutic Area : Pharmacology/Toxicology

                            Study Phase : Preclinical

                            Sponsor : National Institutes of Health

                            Deal Size : $4.6 million

                            Deal Type : Funding

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                            NanoSurface Biomedical Awarded $1.9M in Funding from NIH

                            Details : The SBIR funding will be used to develop NanoSurface’s innovative platform for modeling and assessing human cardiac function on-a-chip.

                            Product Name : Undisclosed

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            March 03, 2020

                            Lead Product(s) : Human Ipsc-Derived Cardiac Tissues

                            Therapeutic Area : Pharmacology/Toxicology

                            Highest Development Status : Preclinical

                            Sponsor : National Institutes of Health

                            Deal Size : $4.6 million

                            Deal Type : Funding

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                            05

                            Incyte Corporation

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                            Incyte Corporation

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                            Lead Product(s) : Ruxolitinib Phosphate

                            Therapeutic Area : Pharmacology/Toxicology

                            Study Phase : Preclinical

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            Novartis, Incyte to test Jakavi for coronavirus-linked cytokine storm

                            Details : Novartis plans to initiate a Phase III clinical trial in collaboration with Incyte to evaluate the use of Jakavi for treatment of severe immune overreaction called cytokine storm in COVID-19.

                            Product Name : Jakavi

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            February 04, 2020

                            Lead Product(s) : Ruxolitinib Phosphate

                            Therapeutic Area : Pharmacology/Toxicology

                            Highest Development Status : Preclinical

                            Sponsor : Novartis Pharmaceuticals Corporation

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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