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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : Sevelamer Hydrochloride

                          Therapeutic Area : Nephrology

                          Study Phase : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : USFDA approved generic version of Sevelamer Carbonate which is used to manage elevated levels of phosphate in the blood of patients with chronic kidney disease.

                          Product Name : Renvela-Generic

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          May 10, 2024

                          Lead Product(s) : Sevelamer Hydrochloride

                          Therapeutic Area : Nephrology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Strides Pharma Science

                          02

                          Lead Product(s) : Sevelamer Hydrochloride

                          Therapeutic Area : Nephrology

                          Study Phase : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : USFDA approved generic version of Sevelamer Carbonate which is used to manage elevated levels of phosphate in the blood of patients with chronic kidney disease.

                          Product Name : Renvela-Generic

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          September 09, 2023

                          Lead Product(s) : Sevelamer Hydrochloride

                          Therapeutic Area : Nephrology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Strides Pharma Science

                          03

                          Lead Product(s) : Potassium Chloride

                          Therapeutic Area : Nephrology

                          Study Phase : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : USFDA approved generic version of potassium chloride oral solution, which s indicated for the treatment and prophylaxis of hypokalemia with or without metabolic alkalosis.

                          Product Name : Potassium Chloride-Generic

                          Product Type : Vitamins/Minerals/Inorganic Salts

                          Upfront Cash : Inapplicable

                          November 18, 2022

                          Lead Product(s) : Potassium Chloride

                          Therapeutic Area : Nephrology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Strides Pharma Science

                          04

                          Lead Product(s) : Potassium Chloride

                          Therapeutic Area : Nephrology

                          Study Phase : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Generic version of Potassium Chloride for Oral Solution USP, 20 mEq has been approved to prevent or to treat patients suffering with low blood levels of potassium (hypokalemia).

                          Product Name : Potassium Chloride-Generic

                          Product Type : Vitamins/Minerals/Inorganic Salts

                          Upfront Cash : Inapplicable

                          January 28, 2022

                          Lead Product(s) : Potassium Chloride

                          Therapeutic Area : Nephrology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Granules India

                          05

                          Lead Product(s) : Potassium Chloride

                          Therapeutic Area : Nephrology

                          Study Phase : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : The Potassium Chloride product is bioequivalent and therapeutically equivalent to the Reference Listed Drug (RLD), Potassium Chloride for Oral Solution USP, 20 mEq, of Pharma Research Software Solution, LLC.

                          Product Name : Potassium Chloride-Generic

                          Product Type : Vitamins/Minerals/Inorganic Salts

                          Upfront Cash : Inapplicable

                          March 15, 2021

                          Lead Product(s) : Potassium Chloride

                          Therapeutic Area : Nephrology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Strides Pharma Science

                          06

                          Lead Product(s) : Potassium Chloride

                          Therapeutic Area : Nephrology

                          Study Phase : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Generic version of Potassium Chloride capsule USP, 8 &1 0 mEq has been approved to prevent or to treat patients suffering with low blood levels of potassium (hypokalemia).

                          Product Name : Potassium Chloride-Generic

                          Product Type : Vitamins/Minerals/Inorganic Salts

                          Upfront Cash : Inapplicable

                          February 17, 2021

                          Lead Product(s) : Potassium Chloride

                          Therapeutic Area : Nephrology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Granules India

                          07

                          Lead Product(s) : Potassium Chloride

                          Therapeutic Area : Nephrology

                          Study Phase : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Generic version of Potassium Chloride for Oral Solution USP, 20 mEq has been approved to prevent or to treat patients suffering with low blood levels of potassium (hypokalemia).

                          Product Name : Potassium Chloride-Generic

                          Product Type : Vitamins/Minerals/Inorganic Salts

                          Upfront Cash : Inapplicable

                          February 01, 2021

                          Lead Product(s) : Potassium Chloride

                          Therapeutic Area : Nephrology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Granules India

                          08

                          Lead Product(s) : Potassium Chloride

                          Therapeutic Area : Nephrology

                          Study Phase : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Generic version of Potassium Chloride tablets has been approved to prevent or to treat patients suffering with low blood levels of potassium (hypokalemia).

                          Product Name : Potassium Chloride-Generic

                          Product Type : Vitamins/Minerals/Inorganic Salts

                          Upfront Cash : Inapplicable

                          October 22, 2020

                          Lead Product(s) : Potassium Chloride

                          Therapeutic Area : Nephrology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Granules India

                          09

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Corstasis and USHV to co-develop value-based care for outpatient fluid overload in CHF, liver, and kidney disease using Enbumyst (bumetanide nasal spray).

                          Product Name : Enbumyst

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          September 25, 2025

                          Lead Product(s) : Bumetanide

                          Therapeutic Area : Nephrology

                          Highest Development Status : Approved FDF

                          Sponsor : USHV

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          10

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : Enbumyst (bumetanide) appears to block the active reabsorption of chloride and possibly sodium, resulting in excretion of sodium, chloride, and water and, hence, diuresis.

                          Product Name : Enbumyst

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          September 18, 2025

                          Lead Product(s) : Bumetanide

                          Therapeutic Area : Nephrology

                          Highest Development Status : Approved FDF

                          Sponsor : Aptar Pharma

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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