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Find Novel Immunology Drugs in Clinical Development

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            Lead Product(s): Undisclosed

            Therapeutic Area: Immunology

            Highest Development Status: Undisclosed Product Type: Small molecule

            Partner/Sponsor/Collaborator: Bridge Biotherapeutics

            Deal Size: $1,080.0 million Upfront Cash: Undisclosed

            Deal Type: Collaboration March 09, 2020

            Details:

            Under the agreement, Atomwise will evaluate and initiate programs for Pellino E3 ubiquitin ligases and other targets nominated by Bridge.

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            Lead Product(s): ADP101

            Therapeutic Area: Immunology

            Highest Development Status: Undisclosed Product Type: Large molecule

            Partner/Sponsor/Collaborator: Gurnet Point Capital

            Deal Size: $60.0 million Upfront Cash: Undisclosed

            Deal Type: Series C Financing February 20, 2020

            Details:

            Proceeds to support clinical advancement of ADP101, a broad-spectrum oral biopharmaceutical candidate targeting food allergy.

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            Lead Product(s): Undisclosed

            Therapeutic Area: Immunology

            Highest Development Status: Undisclosed Product Type: Small molecule

            Partner/Sponsor/Collaborator: Syncona

            Deal Size: $53.6 million Upfront Cash: Undisclosed

            Deal Type: Series A Financing February 17, 2020

            Details:

            Proceeds from this financing will allow the Company to progress a pipeline of small molecule therapeutics for patients suffering from immunological and genetic disorders.

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            Lead Product(s): Treg therapy

            Therapeutic Area: Immunology

            Highest Development Status: Undisclosed Product Type: Large molecule

            Partner/Sponsor/Collaborator: Lyell Immunopharma

            Deal Size: $40.0 million Upfront Cash: Undisclosed

            Deal Type: Series A Financing February 06, 2020

            Details:

            The series A funding is to advance regulatory T cell therapy in autoimmune and degenerative diseases.

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            Lead Product(s): Stefin A

            Therapeutic Area: Immunology

            Highest Development Status: Undisclosed Product Type: Large molecule

            Partner/Sponsor/Collaborator: AffyXell Therapeutics

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Collaboration February 03, 2020

            Details:

            License agreement to utilise Affimer® proteins in next generation cell and gene therapies.

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            Lead Product(s): Undisclosed

            Therapeutic Area: Immunology

            Highest Development Status: Undisclosed Product Type: Undisclosed

            Partner/Sponsor/Collaborator: RA Capital Management

            Deal Size: $50.0 million Upfront Cash: Undisclosed

            Deal Type: Series A Financing January 27, 2020

            Details:

            The funding will support company's lead therapeutic approach that inhibits Gasdermin D, which has been recently discovered as a key target at the core of multiple inflammatory cell death pathways.

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            Lead Product(s): T cells therapy

            Therapeutic Area: Immunology

            Highest Development Status: Undisclosed Product Type: Large molecule

            Partner/Sponsor/Collaborator: Vida Ventures

            Deal Size: $25.0 million Upfront Cash: Undisclosed

            Deal Type: Series A Financing January 13, 2020

            Details:

            Proceeds from the financing will be used to advance Kyverna's therapeutic strategy which combines advanced T cell engineering and synthetic biology technologies to suppress and eliminate autoreactive immune cells at the root cause of inflammatory disease.

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            Lead Product(s): T cells therapy

            Therapeutic Area: Immunology

            Highest Development Status: Undisclosed Product Type: Large molecule

            Partner/Sponsor/Collaborator: Gilead Sciences

            Deal Size: $587.5 million Upfront Cash: $17.5 million

            Deal Type: Collaboration January 13, 2020

            Details:

            Kyverna will be conducting research activities and initial clinical studies through proof-of-concept and Gilead will be granted an option for further development and commercialization of these programs.

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            Lead Product(s): Antibodies

            Therapeutic Area: Immunology

            Highest Development Status: Undisclosed Product Type: Large molecule

            Partner/Sponsor/Collaborator: Pandion Therapeutics

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Licensing Agreement January 13, 2020

            Details:

            Under the agreement, Pandion will be able to use Ligand’s full OmniAb antibody discovery platform which includes OmniRat®, OmniFlic®, OmniMouse®, OmniChicken® and OmniClic™.

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            Lead Product(s): Mesenchymal stem cells

            Therapeutic Area: Immunology

            Highest Development Status: Undisclosed Product Type: Large molecule

            Partner/Sponsor/Collaborator: Avacta Group

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Licensing Agreement January 08, 2020

            Details:

            The joint venture will develop a new class of MSCs that are primed to produce Affimer proteins to enhance the immune-modulatory effect when administered to patients.

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