[{"orgOrder":0,"company":"Aposcience","sponsor":"FGK Clinical Research","pharmaFlowCategory":"DU","therapeuticArea":"Podiatry","country":"AUSTRIA","productType":"Undisclosed","year":"2020","type":"Inapplicable","leadProduct":"APO-2","moa":"Undisclosed","graph1":"Podiatry","graph2":"Phase I\/ Phase II","graph3":"Aposcience","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Podiatry","amount2New":0,"dosageForm":"Gel","sponsorNew":"Aposcience \/ FGK Clinical Research","highestDevelopmentStatusID":"7","companyTruncated":"Aposcience \/ FGK Clinical Research"},{"orgOrder":0,"company":"Supergenics Life Science Sdn. Bhd.","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Podiatry","country":"","productType":"Cell and Gene therapy","year":"2024","type":"Inapplicable","leadProduct":"Allogeneic Mesenchymal Stem Cell","moa":"Undisclosed","graph1":"Podiatry","graph2":"Phase I\/ Phase II","graph3":"Supergenics Life Science Sdn. Bhd.","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Podiatry","amount2New":0,"dosageForm":"Injection","sponsorNew":"Supergenics Life Science Sdn. Bhd. \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Supergenics Life Science Sdn. Bhd. \/ Inapplicable"},{"orgOrder":0,"company":"Aurealis Therapeutics","sponsor":"Xbiome","pharmaFlowCategory":"D","therapeuticArea":"Podiatry","country":"SWITZERLAND","productType":"Cell and Gene therapy","year":"2022","type":"Collaboration","leadProduct":"AUP-16","moa":"FGF2","graph1":"Podiatry","graph2":"Phase I\/ Phase II","graph3":"Aurealis Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Podiatry","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Aurealis Therapeutics \/ Xbiome","highestDevelopmentStatusID":"7","companyTruncated":"Aurealis Therapeutics \/ Xbiome"},{"orgOrder":0,"company":"Heron Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Podiatry","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"HTX-034","moa":"COX-2","graph1":"Podiatry","graph2":"Phase I\/ Phase II","graph3":"Heron Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Podiatry","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Heron Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Heron Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"SaNOtize","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Podiatry","country":"CANADA","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Nitric Oxide","moa":"Soluble guanylate cyclase","graph1":"Podiatry","graph2":"Phase I\/ Phase II","graph3":"SaNOtize","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Podiatry","amount2New":0,"dosageForm":"Solution","sponsorNew":"SaNOtize \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"SaNOtize \/ Inapplicable"},{"orgOrder":0,"company":"FibroBiologics","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Podiatry","country":"U.S.A","productType":"Undisclosed","year":"2025","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Podiatry","graph2":"Phase I\/ Phase II","graph3":"FibroBiologics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Podiatry","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"FibroBiologics \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"FibroBiologics \/ Undisclosed"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          IFSCC
                          Not Confirmed
                          IFSCC
                          Not Confirmed

                          Details : This drug candidate is currently being evaluated in Phase I/ Phase II clinical studies for the treatment of Diabetic Foot.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          July 31, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Podiatry

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          IFSCC
                          Not Confirmed
                          IFSCC
                          Not Confirmed

                          Details : RECCE 327 (R327) is a novel topical Bacterial ATP production inhibitor which is under phase 1/2 clinical development for the treatment of Diabetic Foot Infections.

                          Product Name : Undisclosed

                          Product Type : Antibiotic

                          Upfront Cash : Inapplicable

                          February 27, 2024

                          Lead Product(s) : R327

                          Therapeutic Area : Podiatry

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Supergenics Life Science Sdn. Bhd.

                          Country arrow
                          IFSCC
                          Not Confirmed

                          Supergenics Life Science Sdn. Bhd.

                          Country arrow
                          IFSCC
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          January 30, 2024

                          Lead Product(s) : Allogeneic Mesenchymal Stem Cell

                          Therapeutic Area : Podiatry

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          IFSCC
                          Not Confirmed
                          IFSCC
                          Not Confirmed

                          Details : RECCE 327 (R327) is a novel topical Bacterial ATP production inhibitor which is under phase 1/2 clinical development for the treatment of Diabetic Foot Infections.

                          Product Name : Undisclosed

                          Product Type : Antibiotic

                          Upfront Cash : Inapplicable

                          January 23, 2024

                          Lead Product(s) : R327

                          Therapeutic Area : Podiatry

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          IFSCC
                          Not Confirmed
                          IFSCC
                          Not Confirmed

                          Details : RECCE 327 (R327) is a rapid and irreversible bactericidal against gram-negative escherichia coli (E. coli) bacteria, in both active and stationary phase cells, which is being investigated as a treatment for Diabetic Foot Infections.

                          Product Name : Undisclosed

                          Product Type : Antibiotic

                          Upfront Cash : Inapplicable

                          August 24, 2023

                          Lead Product(s) : R327

                          Therapeutic Area : Podiatry

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          IFSCC
                          Not Confirmed
                          IFSCC
                          Not Confirmed

                          Details : The company’s work with Murdoch Children's has already played a pivotal role in the delivery of results surrounding ongoing pre-clinical programs, generating R327 (RECCE 327) data demonstrating strong bactericidal activity against a range of deadly pat...

                          Product Name : Undisclosed

                          Product Type : Antibiotic

                          Upfront Cash : Undisclosed

                          December 19, 2022

                          Lead Product(s) : R327

                          Therapeutic Area : Podiatry

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Murdoch Children’s Research Institute

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          07

                          IFSCC
                          Not Confirmed
                          IFSCC
                          Not Confirmed

                          Details : RECCE® 327 (R327) is one of the first new classes of antibiotics in over 30 years with a universal mechanism of action that allow its compounds to continuously kill bacteria and multi-drug resistant superbugs.

                          Product Name : Undisclosed

                          Product Type : Antibiotic

                          Upfront Cash : Inapplicable

                          December 12, 2022

                          Lead Product(s) : R327

                          Therapeutic Area : Podiatry

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          IFSCC
                          Not Confirmed
                          IFSCC
                          Not Confirmed

                          Details : Under the terms of the license and collaboration agreement, Xbiome acquires exclusive development and commercial rights for all human use to Aurealis clinical stage DFU drug candidate AUP-16 in Mainland China, Hong Kong, Macao, and Taiwan.

                          Product Name : Undisclosed

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          January 28, 2022

                          Lead Product(s) : AUP-16

                          Therapeutic Area : Podiatry

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Xbiome

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          09

                          Technophage, SA

                          Country arrow
                          IFSCC
                          Not Confirmed

                          Technophage, SA

                          Country arrow
                          IFSCC
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Microorganism

                          Upfront Cash : Inapplicable

                          March 18, 2021

                          Lead Product(s) : TP-102

                          Therapeutic Area : Podiatry

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : VectorB2B

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          IFSCC
                          Not Confirmed
                          IFSCC
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          February 16, 2021

                          Lead Product(s) : Nitric Oxide

                          Therapeutic Area : Podiatry

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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