Lead Product(s) : Bilastine
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Bilastine 20 mg ODT vs Bilaxten 20 mg ODT Bioavailability Under Fasting In Healthy Adults
Details : Bilastine is a Other Small Molecule drug candidate, which is currently being evaluated in Phase I clinical studies for the treatment of Rhinoconjunctivitis, Allergic.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
June 29, 2025
Lead Product(s) : Bilastine
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : CIL001
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Study Phase : Phase I
Sponsor : Shionogi
Deal Size : $16.0 million
Deal Type : Agreement
Japan's Shionogi Inks €400 M Deal with French Firm Cilcare
Details : Through the agreement with Cilcare to acquire the exclusive license to develop, manufacture, and commercialize CIL001 for the treatment of patients with hearing loss.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : $16.0 million
June 10, 2024
Lead Product(s) : CIL001
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Highest Development Status : Phase I
Sponsor : Shionogi
Deal Size : $16.0 million
Deal Type : Agreement
Lead Product(s) : AUR-201
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Subcutaneous Implant Combination Product (AUR-201) in Patients With Unilateral Microtia (Australia)
Details : AUR-201 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Congenital Microtia.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
January 25, 2024
Lead Product(s) : AUR-201
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : INI-2004
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Study Phase : Phase I
Sponsor : Avance Clinical
Deal Size : Inapplicable
Deal Type : Inapplicable
Trial of INI-2004 in Healthy Volunteers and Participants With Allergic Rhinitis.
Details : INI-2004 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Rhinitis, Allergic, Perennial.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
September 14, 2023
Lead Product(s) : INI-2004
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Highest Development Status : Phase I
Sponsor : Avance Clinical
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : HG205
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Study Phase : Phase I
Sponsor : Gene Therapy Research Center, Shariati Hospital, Tehran University of Medical Sciences, Iran
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : HG205 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Hearing Loss, Congenital.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Inapplicable
September 06, 2023
Lead Product(s) : HG205
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Highest Development Status : Phase I
Sponsor : Gene Therapy Research Center, Shariati Hospital, Tehran University of Medical Sciences, Iran
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : SPT-2101
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Study Phase : Phase I
Sponsor : Savoir Capital
Deal Size : $8.2 million
Deal Type : Financing
Spiral Therapeutics Completes $8.25M Financing and Initiates Phase 2 Trial in Meniere's Disease
Details : SPT-2101 is a sustained-release steroid formulation designed for precise inner ear administration using Spiral's novel delivery procedure. Spiral recently completed enrollment of an open label pilot clinical study of SPT-2101 in 10 patients with Meniere'...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
January 10, 2023
Lead Product(s) : SPT-2101
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Highest Development Status : Phase I
Sponsor : Savoir Capital
Deal Size : $8.2 million
Deal Type : Financing
Lead Product(s) : FX-345
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
First in Human Safety Study of FX-345 in Adults With Sensorineural Hearing Loss
Details : FX-345 is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Hearing Loss, Sensorineural.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 23, 2022
Lead Product(s) : FX-345
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : FX-345
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : FX-345 is a combination of two small molecules and, similar to Frequency’s lead hearing candidate FX-322, is designed to restore inner ear cells needed for hearing.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 15, 2022
Lead Product(s) : FX-345
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : ACOU085
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Study Phase : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ACOU085 is a proprietary small molecule, etiology-agnostic otoprotective drug candidate, expected to finish a first-in-man clinical Phase 1b study by late 2022 using standard transtympanic administration of a slow-release gel formulation.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
November 24, 2022
Lead Product(s) : ACOU085
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Highest Development Status : Phase I
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Glycerine
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Study Phase : Phase I
Sponsor : Dalhousie University
Deal Size : Inapplicable
Deal Type : Inapplicable
The Effects of Glycerol as an Optical Clearing Agent for Visualization of the Middle Ear
Details : Glycerol is a Other Small Molecule drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Tympanosclerosis.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
August 11, 2022
Lead Product(s) : Glycerine
Therapeutic Area : Otolaryngology (Ear, Nose, Throat)
Highest Development Status : Phase I
Sponsor : Dalhousie University
Deal Size : Inapplicable
Deal Type : Inapplicable