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Children's Hospital | Baoding Children's Hospital | Xuzhou Children Hospital | Chengdu Women's and Children's Central Hospital | Children's Hospital of Heibei Province | Beijing Clinical Service Center","highestDevelopmentStatusID":"1","companyTruncated":"Novozymes \/ Beijing Children's Hospital | Baoding Children's Hospital | Xuzhou Children Hospital | Chengdu Women's and Children's Central Hospital | Children's Hospital of Heibei Province | Beijing Clinical Service Center"},{"orgOrder":0,"company":"Novozymes","sponsor":"Universidad Iberoamericana A.C., Mexico | Linus Biotechnology Inc","pharmaFlowCategory":"DU","therapeuticArea":"Pharmacology\/Toxicology","country":"DENMARK","productType":"Probiotic","year":"2022","type":"Inapplicable","leadProduct":"Lactobacillus Plantarum DSM 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Institute","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Toxicology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"The Wistar Institute \/ Jubilant Therapeutics","highestDevelopmentStatusID":"4","companyTruncated":"The Wistar Institute \/ Jubilant Therapeutics"}]

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                          01

                          Lead Product(s) : Acetylcysteine

                          Therapeutic Area : Pharmacology/Toxicology

                          Study Phase : Approved FDF

                          Sponsor : Glenmark Pharmaceuticals

                          Deal Size : Undisclosed

                          Deal Type : Acquisition

                          Details : Glenmark has acquired generic version of Acetadote (acetylcysteine) injection from Aspen Pharma. It is an antidote for acetaminophen overdose indicated to prevent or lessen hepatic injury.

                          Product Name : Acetadote-Generic

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          March 03, 2025

                          Lead Product(s) : Acetylcysteine

                          Therapeutic Area : Pharmacology/Toxicology

                          Highest Development Status : Approved FDF

                          Sponsor : Glenmark Pharmaceuticals

                          Deal Size : Undisclosed

                          Deal Type : Acquisition

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                          02

                          Lead Product(s) : GP1681

                          Therapeutic Area : Pharmacology/Toxicology

                          Study Phase : Phase I/ Phase II

                          Sponsor : CytoAgents

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

                          Details : The collaboration aims to focus on the development of GP1681 (CTO1681), which is a small molecule inhibitor of cytokine release targeting the NF-kB signaling pathway via the activation of the EP4 receptor. It is under development for treatment of cytokin...

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          April 28, 2020

                          Lead Product(s) : GP1681

                          Therapeutic Area : Pharmacology/Toxicology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : CytoAgents

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

                          Quotient

                          03

                          BioJapan
                          Not Confirmed
                          BioJapan
                          Not Confirmed

                          Details : The agreement creates an exclusive partnership for a portfolio of oncology-related medications, including CNX Therapeutics’ Cardioxane (dexrazoxane) and Savene (dexrazoxane).

                          Product Name : Cardioxane

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          August 26, 2025

                          Lead Product(s) : Dexrazoxane

                          Therapeutic Area : Pharmacology/Toxicology

                          Highest Development Status : Approved FDF

                          Sponsor : Erkim

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          04

                          BioJapan
                          Not Confirmed
                          BioJapan
                          Not Confirmed

                          Details : Avtozma (tocilizumab) is an interleukin-6 (IL-6) receptor antagonist indicated for treatment of cytokine release syndrome.

                          Product Name : Avtozma

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          August 11, 2025

                          Lead Product(s) : Tocilizumab

                          Therapeutic Area : Pharmacology/Toxicology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Jianersheng Pharmaceutical Technology

                          Country arrow
                          BioJapan
                          Not Confirmed

                          Jianersheng Pharmaceutical Technology

                          Country arrow
                          BioJapan
                          Not Confirmed

                          Lead Product(s) : GMDTC

                          Therapeutic Area : Pharmacology/Toxicology

                          Study Phase : Phase II

                          Sponsor : Guangdong Provincial Hospital for Occupational Disease Prevention and Treatment

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : GMDTC is a Antibiotic drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Cadmium Poisoning.

                          Product Name : Undisclosed

                          Product Type : Antibiotic

                          Upfront Cash : Inapplicable

                          July 09, 2025

                          Lead Product(s) : GMDTC

                          Therapeutic Area : Pharmacology/Toxicology

                          Highest Development Status : Phase II

                          Sponsor : Guangdong Provincial Hospital for Occupational Disease Prevention and Treatment

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          BioJapan
                          Not Confirmed
                          BioJapan
                          Not Confirmed

                          Details : CTO1681 is a GPCR agonist, small molecule drug candiate, which is being evaluated for the treatment of cytokine release syndrome.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          April 24, 2025

                          Lead Product(s) : CTO1681

                          Therapeutic Area : Pharmacology/Toxicology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          BioJapan
                          Not Confirmed
                          BioJapan
                          Not Confirmed

                          Details : The funding aims to advance the the manufacturing of DuoDote (atropine and pralidoxime chloride). It is indicated for the treatment of poisoning by organophosphorus nerve agents.

                          Product Name : Duodote

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          January 16, 2025

                          Lead Product(s) : Atropine,Pralidoxime Chloride

                          Therapeutic Area : Pharmacology/Toxicology

                          Highest Development Status : Approved FDF

                          Sponsor : US Department Of Health And Human Services

                          Deal Size : $129.0 million

                          Deal Type : Funding

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                          08

                          BioJapan
                          Not Confirmed
                          BioJapan
                          Not Confirmed

                          Details : ANEB-001 (selonabant) is a CB1 receptor inhibitor, being evaluated for the potential use as an emergency treatment of acute cannabis-induced toxicities, including cannabis-induced CNS depression.

                          Product Name : Undisclosed

                          Product Type : Controlled Substance

                          Upfront Cash : Inapplicable

                          December 23, 2024

                          Lead Product(s) : Selonabant

                          Therapeutic Area : Pharmacology/Toxicology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          BioJapan
                          Not Confirmed
                          BioJapan
                          Not Confirmed

                          Details : Pedmarqsi (anhydrous sodium thiosulfate) is the first and only intracellular oxidative stress inhibitor, treatment available in England for cisplatin-induced ototoxicity in 1 month-17 years of age.

                          Product Name : Pedmarqsi

                          Product Type : Vitamins/Minerals/Inorganic Salts

                          Upfront Cash : Inapplicable

                          December 20, 2024

                          Lead Product(s) : Sodium Thiosulfate

                          Therapeutic Area : Pharmacology/Toxicology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          BioJapan
                          Not Confirmed
                          BioJapan
                          Not Confirmed

                          Details : Acetadote (N-acetylcysteine) is a FDA approved drug candidate, which is now being evaluated to prevent or lessen liver injury after ingestion of potentially toxic quantities of acetaminophen.

                          Product Name : Acetadote

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          December 09, 2024

                          Lead Product(s) : Acetylcysteine

                          Therapeutic Area : Pharmacology/Toxicology

                          Highest Development Status : Approved FDF

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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