Drugs in Dev.
Rheumatology
Preclinical

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Lead Product(s) : Undisclosed
Therapeutic Area : Rheumatology
Study Phase : Preclinical
Sponsor : Atlas Venture
Deal Size : $60.0 million
Deal Type : Series B Financing
GRO Bio gathers $60M series B to take gout rival to Krystexxa into clinic
Details : The Proceeds from the financing will be used to advance the Company’s lead program ProGly-Uricase into the clinic for the treatment of refractory gout and to broaden the GRObio pipeline.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
July 19, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Rheumatology
Highest Development Status : Preclinical
Sponsor : Atlas Venture
Deal Size : $60.0 million
Deal Type : Series B Financing

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Lead Product(s) : Undisclosed
Therapeutic Area : Rheumatology
Study Phase : Preclinical
Sponsor : Amgen Inc
Deal Size : $500.0 million
Deal Type : Collaboration
Details : Under the terms of the agreement Horizon received exclusive access to HemoShear's proprietary disease modeling REVEAL-TxTM drug discovery platform to discover new therapeutics for gout.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
September 21, 2021
Lead Product(s) : Undisclosed
Therapeutic Area : Rheumatology
Highest Development Status : Preclinical
Sponsor : Amgen Inc
Deal Size : $500.0 million
Deal Type : Collaboration

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Lead Product(s) : ARO-XDH
Therapeutic Area : Rheumatology
Study Phase : Preclinical
Sponsor : Amgen Inc
Deal Size : Undisclosed
Deal Type : Collaboration
Arrowhead and Horizon Collaborate to Develop RNAi Therapeutic
Details : Arrowhead will conduct all activities through preclinical stages of development of the siRNA therapeutic, ARO-XDH. Horizon will receive a worldwide exclusive license to ARO-XDH and will be wholly responsible for clinical development and commercialization...
Product Name : ARO-XDH
Product Type : Oligonucleotide
Upfront Cash : Undisclosed
June 21, 2021
Lead Product(s) : ARO-XDH
Therapeutic Area : Rheumatology
Highest Development Status : Preclinical
Sponsor : Amgen Inc
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : Mosedipimod
Therapeutic Area : Rheumatology
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The publication reports results from a study, examining a mitigating effect of PLAG on gouty inflammation.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
May 01, 2020
Lead Product(s) : Mosedipimod
Therapeutic Area : Rheumatology
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
