Drugs in Dev.
Pharmacology/Toxicology
Approved FDF

Lead Product(s) : Acetylcysteine
Therapeutic Area : Pharmacology/Toxicology
Study Phase : Approved FDF
Sponsor : Glenmark Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Acquisition
Glenmark Acquires & Launches Acetylcysteine Injection 6gm/30mL Single-Dose Vials
Details : Glenmark has acquired generic version of Acetadote (acetylcysteine) injection from Aspen Pharma. It is an antidote for acetaminophen overdose indicated to prevent or lessen hepatic injury.
Product Name : Acetadote-Generic
Product Type : Miscellaneous
Upfront Cash : Undisclosed
March 03, 2025
Lead Product(s) : Acetylcysteine
Therapeutic Area : Pharmacology/Toxicology
Highest Development Status : Approved FDF
Sponsor : Glenmark Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Acquisition
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Lead Product(s) : Dexrazoxane
Therapeutic Area : Pharmacology/Toxicology
Study Phase : Approved FDF
Sponsor : Erkim
Deal Size : Undisclosed
Deal Type : Agreement
Er-Kim Announces Agreement with CNX Therapeutics to Distribute Oncology Products
Details : The agreement creates an exclusive partnership for a portfolio of oncology-related medications, including CNX Therapeutics’ Cardioxane (dexrazoxane) and Savene (dexrazoxane).
Product Name : Cardioxane
Product Type : Miscellaneous
Upfront Cash : Undisclosed
August 26, 2025
Lead Product(s) : Dexrazoxane
Therapeutic Area : Pharmacology/Toxicology
Highest Development Status : Approved FDF
Sponsor : Erkim
Deal Size : Undisclosed
Deal Type : Agreement

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Lead Product(s) : Tocilizumab
Therapeutic Area : Pharmacology/Toxicology
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
FDA Approves Expanded Indication for Celltrion’s AVTOZMA
Details : Avtozma (tocilizumab) is an interleukin-6 (IL-6) receptor antagonist indicated for treatment of cytokine release syndrome.
Product Name : Avtozma
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
August 11, 2025
Lead Product(s) : Tocilizumab
Therapeutic Area : Pharmacology/Toxicology
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Atropine,Pralidoxime Chloride
Therapeutic Area : Pharmacology/Toxicology
Study Phase : Approved FDF
Sponsor : US Department Of Health And Human Services
Deal Size : $129.0 million
Deal Type : Funding
Kindeva Secures $129M SNS Contract for Nerve Agent Antidote
Details : The funding aims to advance the the manufacturing of DuoDote (atropine and pralidoxime chloride). It is indicated for the treatment of poisoning by organophosphorus nerve agents.
Product Name : Duodote
Product Type : Miscellaneous
Upfront Cash : Undisclosed
January 16, 2025
Lead Product(s) : Atropine,Pralidoxime Chloride
Therapeutic Area : Pharmacology/Toxicology
Highest Development Status : Approved FDF
Sponsor : US Department Of Health And Human Services
Deal Size : $129.0 million
Deal Type : Funding

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Lead Product(s) : Sodium Thiosulfate
Therapeutic Area : Pharmacology/Toxicology
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Fennec Pharmaceuticals Announces NICE Positive Recommendation for Pedmarqsi®
Details : Pedmarqsi (anhydrous sodium thiosulfate) is the first and only intracellular oxidative stress inhibitor, treatment available in England for cisplatin-induced ototoxicity in 1 month-17 years of age.
Product Name : Pedmarqsi
Product Type : Vitamins/Minerals/Inorganic Salts
Upfront Cash : Inapplicable
December 20, 2024
Lead Product(s) : Sodium Thiosulfate
Therapeutic Area : Pharmacology/Toxicology
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Acetylcysteine
Therapeutic Area : Pharmacology/Toxicology
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Acetadote (N-acetylcysteine) is a FDA approved drug candidate, which is now being evaluated to prevent or lessen liver injury after ingestion of potentially toxic quantities of acetaminophen.
Product Name : Acetadote
Product Type : Miscellaneous
Upfront Cash : Inapplicable
December 09, 2024
Lead Product(s) : Acetylcysteine
Therapeutic Area : Pharmacology/Toxicology
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Pyridostigmine
Therapeutic Area : Pharmacology/Toxicology
Study Phase : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Amneal Gains FDA Nod for Pyridostigmine Bromide Extended-Release Tablets
Details : Pyridostigmine Bromide, is a cholinesterase inhibitor small molecule drug administered orally for soman nerve agent poisoning in adults.
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Inapplicable
October 21, 2024
Lead Product(s) : Pyridostigmine
Therapeutic Area : Pharmacology/Toxicology
Highest Development Status : Approved FDF
Sponsor : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable

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Lead Product(s) : Deferoxamine Mesylate
Therapeutic Area : Pharmacology/Toxicology
Study Phase : Approved FDF
Sponsor : Mitem Pharma
Deal Size : Undisclosed
Deal Type : Acquisition
MITEM Pharma Acquires DESFERAL® Rights Backed by TECHLIFE CAPITAL, MACSF
Details : Mitem acquires Desfera (deferoxamine mesylate) products from Novartis. It is indicated for treating iron overload, and forex, following blood transfusions necessary for treating beta-thalassemia.
Product Name : Desfera
Product Type : Miscellaneous
Upfront Cash : Undisclosed
September 25, 2024
Lead Product(s) : Deferoxamine Mesylate
Therapeutic Area : Pharmacology/Toxicology
Highest Development Status : Approved FDF
Sponsor : Mitem Pharma
Deal Size : Undisclosed
Deal Type : Acquisition

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Lead Product(s) : Glucarpidase
Therapeutic Area : Pharmacology/Toxicology
Study Phase : Approved FDF
Sponsor : SERB Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Agreement
M8 Pharmaceuticals Signs Exclusive Agreement with SERB to Bring Voraxaze® to Latin America
Details : M8 will register, market and commercialize SERB's supportive oncology product Voraxaze (glucarpidase), a carboxypeptidase that reduces toxic plasma methotrexate concentration, in Latin America.
Product Name : Voraxaze
Product Type : Enzyme
Upfront Cash : Undisclosed
March 20, 2024
Lead Product(s) : Glucarpidase
Therapeutic Area : Pharmacology/Toxicology
Highest Development Status : Approved FDF
Sponsor : SERB Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Agreement

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Lead Product(s) : Atropine,Pralidoxime Chloride
Therapeutic Area : Pharmacology/Toxicology
Study Phase : Approved FDF
Sponsor : ASPR
Deal Size : $9.9 million
Deal Type : Agreement
Details : Under the agreement, Meridian will supply DuoDote to the Administration for Strategic Preparedness and Response within the United States. DuoDote® is an FDA-approved dual-chamber autoinjector (atropine and pralidoxime chloride) chemical nerve agent anti...
Product Name : DuoDote
Product Type : Miscellaneous
Upfront Cash : Undisclosed
November 14, 2023
Lead Product(s) : Atropine,Pralidoxime Chloride
Therapeutic Area : Pharmacology/Toxicology
Highest Development Status : Approved FDF
Sponsor : ASPR
Deal Size : $9.9 million
Deal Type : Agreement



