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Looking for solubilizer excipients? Find lipids, surfactants, cyclodextrins, organic liquids, etc. for bioavailability and solubility enhancement.

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Applications: Vitamin E TPGS (Tocophersolan) is a multirole excipient for pharmaceutical drug delivery. It can be used as a solubilizer for poorly soluble drugs and as an emulsifying agent, plasticizer, stabilizer & vehicle for lipid based formulations.

Ingredient(s): Tocophersolan

Dosage Form: Capsule, Injectable / Parenteral, Ophthalmic Solution, Nasal Solution, Tablet

Category: Solubilizers

Route of Administration (Grade): Oral, Parenteral, Nasal, Ophthalmic, Topical
Pharmacopoeia Reference: USP 40 – NF 35

Technical Specifications: Specific Gravity: 1.06 at 50°C to 1.03 at 90°C; Solubility In Water: -20% at 20°C; Viscosity: 390cP at 50°C

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Applications: Advantose® 100 is a spray-dried maltose powder that provides excellent flow, solubility, & tableting properties to oral dosage forms. Maltose is well known for its safety & mouthfeel qualities, especially in chewable tablets & lozenges.

Ingredient(s): Maltose Sugar

Dosage Form: Tablet

Category: Solubilizers

Route of Administration (Grade): Oral
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications: Diluent; It improves hardness & disintegration

Ingredient(s): Maltose Sugar

Dosage Form: Solution

Category: Solubilizers

Route of Administration (Grade): Oral, Parenteral
Pharmacopoeia Reference: USP-NF, JPE, Type IV DMF

Technical Specifications: Maltose is a reducing disaccharide consisting of two glucose molecules linked by an ?-1,4 bond.

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Applications: Binder, Film Coating, SR polymer, solubility enhancement, topical spreading agent

Ingredient(s): Hydroxypropyl Cellulose

Dosage Form: Capsule, Solution, Tablet

Category: Solubilizers

Route of Administration (Grade): Oral
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications: Polysorbate 80 in dry powder form, a solubilizing agent acts as a surfactant and increases the solubility of various oral dosage forms.

Ingredient(s): Magnesium aluminium silicate, Polysorbate 80

Dosage Form: Capsule, Tablet

Category: Solubilizers

Route of Administration (Grade): Oral
Pharmacopoeia Reference: USP-NF, EP, JP & having US DMF

Technical Specifications: Solubilizer in powder form, used in directly compressible dosage forms, Wet granulation, added during lubrication stage

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Applications: Polyoxyl 40 hydrogenated castor oil is used as solubilizer and emulsifying agent.

Ingredient(s): Magnesium Aluminometasilicate, Polyoxyl 40 Hydrogenated Castor Oil

Dosage Form: Capsule, Tablet

Category: Solubilizers

Route of Administration (Grade): Oral
Pharmacopoeia Reference: USP-NF, EP, JP

Technical Specifications: Solubilizer in powder form, used in Directly compressible dosage forms, Wet granulation, added during lubrication stage

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Applications: Ethoxylated fatty acids; Polyoxyl 8 stearate; PEG 8 stearate PEG monostearate. It is mainly used as a solvents & as ointment bases, tablet binders, film coatings, lubricants, etc in various pharmaceutical products.

Ingredient(s): Macrogol 8 Stearate

Dosage Form: Cream / Lotion / Ointment, Topical Film

Category: Solubilizers

Route of Administration (Grade): Topical
Pharmacopoeia Reference: USP-NF, EP

Technical Specifications: Emulsifying surfactant

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Applications: Sorbitan esters, such as sorbitan monostearate is mainly used as surfactants or emulsifying agents in the preparation of emulsions, creams, and ointments for pharmaceutical and cosmetic use and as a solubilizer in various injections.

Ingredient(s): Sorbitan Monostearate

Dosage Form: Cream / Lotion / Ointment, Emulsion, Injectable / Parenteral, Topical Film

Category: Solubilizers

Route of Administration (Grade): Oral, Parenteral, Topical
Pharmacopoeia Reference: USP-NF, EP, JP

Technical Specifications: Non-Ionic Lipophilic surfactant; Emulsifier (w/o emulsions)

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Applications: Guanidine Hydrochloride is a strong protein denaturant that functions as a chaotropic agent. As a denaturant, it acts to unfold proteins and turn them into their original polypeptide chains. it breaks down the structure of proteins.

Ingredient(s): Guanidine Hydrochloride

Dosage Form: Cream / Lotion / Ointment

Category: Solubilizers

Route of Administration (Grade): Topical
Pharmacopoeia Reference: Not Available

Technical Specifications: Bio Excipient Grade