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Anhui Sunhere Pharmaceutical Excipients Co.,Ltd
BASF
BioSpectra
Corel Pharma Chem
Gangwal Chemicals
Huzhou Sunflower Pharmacetuical Co. Ltd
Microlex e.U
Nanjing Bold Chemical
PMC Isochem
Roquette
SPI Pharma
Seppic
Shanghai Shenmei Pharmaceutical Technology Co., Ltd
Shanghai Welltone Material Technology Co., Ltd
The Dow Chemical Company
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Applications: Vitamin E TPGS (Tocophersolan) is a multirole excipient for pharmaceutical drug delivery. It can be used as a solubilizer for poorly soluble drugs and as an emulsifying agent, plasticizer, stabilizer & vehicle for lipid based formulations.
Ingredient(s): Tocophersolan
Dosage Form: Capsule, Injectable / Parenteral, Ophthalmic Solution, Nasal Solution, Tablet
Category: Solubilizers
Technical Specifications: Specific Gravity: 1.06 at 50°C to 1.03 at 90°C; Solubility In Water: -20% at 20°C; Viscosity: 390cP at 50°C
Applications: Its applications include solubilizing proteins from inclusion bodies, increasing solubility of hydrophobic peptides and proteins and denaturing proteins. Urea may be used with guanidine hydrochloride in the refolding of denatured proteins.
Ingredient(s): Urea
Dosage Form: Cream / Lotion / Ointment
Category: Solubilizers
Technical Specifications: Bio Excipient Grade
Solving Formulation Challenges Using Superior Functional Materials
Applications: Advantose® 100 is a spray-dried maltose powder that provides excellent flow, solubility, & tableting properties for oral dosage formulations. Maltose is well known for its safety & mouthfeel qualities, especially in chewable tablets & lozenges.
Ingredient(s): Maltose Sugar
Dosage Form: Tablet
Category: Solubilizers
Technical Specifications: Not Available
Applications: Stabilizer, Cryoprotectant
Ingredient(s): Trehalose Dihydrate Excipient
Dosage Form: Injectable / Parenteral, Solution
Category: Solubilizers
Technical Specifications: Low endotoxin grade non-reducing disaccharide consisting of two glucose molecules linked by an alpha, alpha 1 bond.
Applications: Guanidine Hydrochloride is a strong protein denaturant that functions as a chaotropic agent. As a denaturant, it acts to unfold proteins and turn them into their original polypeptide chains. it breaks down the structure of proteins.
Ingredient(s): Guanidine Hydrochloride
Dosage Form: Cream / Lotion / Ointment
Category: Solubilizers
Technical Specifications: Bio Excipient Grade
Applications: Diluent; It improves hardness & disintegration
Ingredient(s): Maltose Sugar
Dosage Form: Solution
Category: Solubilizers
Technical Specifications: Maltose is a reducing disaccharide consisting of two glucose molecules linked by an ?-1,4 bond.
Applications: Binder, Film Coating, SR polymer, solubility enhancement, topical spreading agent
Ingredient(s): Hydroxypropyl Cellulose
Dosage Form: Capsule, Solution, Tablet
Category: Solubilizers
Technical Specifications: Not Available
Applications: Polysorbate 80 in dry powder form
Ingredient(s): Magnesium aluminium silicate, Polysorbate 80
Category: Solubilizers
Technical Specifications: Solubilizer in powder form, used in directly compressible dosage forms, Wet granulation, added during lubrication stage
Applications: Polyoxyl 40 hydrogenated castor oil In dry powder form
Ingredient(s): MAGNESIUM ALUMINOMETASILICATE, Polyoxyl 40 Hydrogenated Castor Oil
Category: Solubilizers
Technical Specifications: Solubilizer in powder form, used in Directly compressible dosage forms, Wet granulation, added during lubrication stage
Applications: Ethoxylated fatty acids; Polyoxyl 8 stearate; PEG 8 stearate PEG monostearate
Ingredient(s): Macrogol 8 Stearate
Dosage Form: Cream / Lotion / Ointment, Topical Film
Category: Solubilizers
Technical Specifications: Emulsifying surfactant
Applications: Sorbitan Esters / SPANs
Ingredient(s): Sorbitan Monostearate
Dosage Form: Cream / Lotion / Ointment, Emulsion, Injectable / Parenteral, Topical Film
Category: Solubilizers
Technical Specifications: Non-Ionic Lipophilic surfactant; Emulsifier (w/o emulsions)
Applications: Sorbitan Esters / SPANs
Ingredient(s): Sorbitan Monolaurate
Dosage Form: Cream / Lotion / Ointment, Emulsion, Injectable / Parenteral
Category: Solubilizers
Technical Specifications: Non-Ionic Lipophilic Surfactant; Emulsifier (w/o emulsions)
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Applications: Solubility enhancement, Spray-Dried Dispersion (SDD), Hot Melt Extrusion (HME)
Ingredient(s): Hydroxypropyl methylcellulose acetate succinate
Dosage Form: Tablet
Category: Solubilizers
Technical Specifications: Not Available
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Applications: Solubility enhancement, Spray-Dried Dispersion (SDD), Hot Melt Extrusion (HME)
Ingredient(s): Hydroxypropyl Methylcellulose
Dosage Form: Tablet
Category: Solubilizers
Technical Specifications: Not Available
Applications: Sorbitan Esters / SPANs
Ingredient(s): sorbitan oleate
Dosage Form: Cream / Lotion / Ointment, Emulsion, Injectable / Parenteral, Solution, Topical Film
Category: Solubilizers
Technical Specifications: Non-Ionic Lipophilic surfactant; Emulsifier (w/o emulsions)
Applications: Ethoxylated fatty acids; Polyoxyl 40 stearate; PEG 40 stearate
Ingredient(s): Macrogol 40 Stearate
Dosage Form: Cream / Lotion / Ointment, Topical Film
Category: Solubilizers
Technical Specifications: Emulsifying Surfactant
Applications: Chemical structure was rationally designed to maximize safety and optimize interaction to improve the solubility, stability, bio availability or lessen volatility, irritation, smell or taste.
Ingredient(s): Betadex Sulfobutyl Ether Sodium Excipient
Dosage Form: Injectable / Parenteral, Ophthalmic Solution, Nasal Solution, Topical Film
Category: Solubilizers
Technical Specifications: Captisol® is a polyanionic beta-cyclodextrin derivative with a sodium sulfonate salt separated from the lipophilic cavity by a butyl ether spacer group, or sulfobutylether (SBE). Relative to beta-cyclodextrin, Captisol® provides higher interaction charact
Applications: Enteric/ Delayed Release Matrix and Solubility Enhancement
Ingredient(s): Methacrylic Acid - Ethyl Acrylate Copolymer
Category: Solubilizers
Technical Specifications: Methylacryli acid and Ethyl Acrylate copolymer (1:1) Type A
Applications: Stabilization/Complexation/Taste masking/Encapsulation/Odour masking
Ingredient(s): Hydroxypropyl Betacyclodextrin
Dosage Form: Capsule, Ophthalmic Solution, Solution, Tablet
Category: Solubilizers
Technical Specifications: Not Available
Applications: Kovidone- K series products posses excellent binding, film-forming, dispersing, and thickning properties and are widely used in the following dosage forms. BinderSolubilizerCoating agentSuspending, Stabilizing or viscocity modifying agent
Ingredient(s): Polyvinylpyrrolidone, Povidone
Category: Solubilizers
Technical Specifications: PVP K-K-30/ K-17/ K19/ K25/ K90
Applications: Super disintegrate, Solublity enhancer, Suspension stabilizer, Complexing agent, Low peroxide content, Long term stability
Ingredient(s): Crospovidone
Category: Solubilizers
Technical Specifications: Crospovidone (Type-A/B)- USP-NF / Ph. Eur. / BP / IP
Applications: Polysorbates / TWEENs
Ingredient(s): Polysorbate 20
Dosage Form: Capsule, Cream / Lotion / Ointment, Tablet, Topical Film
Category: Solubilizers
Technical Specifications: Non-Ionic Hydrophilic surfactant, Emulsifier (o/w emulsion), Solubilizer
Applications: Polysorbates / TWEENs
Ingredient(s): Polysorbate 60
Dosage Form: Capsule, Cream / Lotion / Ointment, Tablet
Category: Solubilizers
Technical Specifications: Non-Ionic Hydrophilic surfactant, Emulsifier (o/w emulsion), Solubilizer
Applications: Polysorbates / TWEENs
Ingredient(s): Polysorbate 80
Dosage Form: Capsule, Cream / Lotion / Ointment, Tablet
Category: Solubilizers
Technical Specifications: Non-Ionic Hydrophilic surfactant, Emulsifier (o/w emulsion), Solubilizer
Applications: Solubiliser, Gelling Agent, Dispersing Agent, Lubricant, Wetting Agent
Ingredient(s): Poloxamer 407
Dosage Form: Injectable / Parenteral, Ophthalmic Solution, Tablet, Topical Film
Category: Solubilizers
Technical Specifications: Versatile excipient having multitude uses in Pharma, Nutra, Cosmetic, Automobile etc
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Applications: It is used as a suspending agent.
Ingredient(s): Carbomer Excipient
Category: Solubilizers
Technical Specifications: Not Available
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Applications: It is used as solubilizers for paclitaxel, cyclosporine, vitamin K1.
Ingredient(s): Polyoxyl 35 Castor Oil
Dosage Form: Injectable / Parenteral
Category: Solubilizers
Technical Specifications: Not Available
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Applications: Sorbitan Monooleate (Span 80) is used as oily emulsifier, solubilizer, thickener.
Ingredient(s): Sorbitan Monooleate
Dosage Form: Capsule, Tablet, Transdermal patches
Category: Solubilizers
Technical Specifications: Not Available
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Applications: Solubilizer, Dissolution Improver, Emulsifier, Masking Agent, Moisturizer, Aerosol Formulations
Ingredient(s): Polyoxyl 35 Hydrogenated Castor Oil
Dosage Form: Emulsion, Injectable / Parenteral, Solution, Suspension
Category: Solubilizers
Technical Specifications: Not Available
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Applications: Povidone K30 is mainly used as binder for tablet and pellet,dissolving assistant for injection,flow assistant for capsule,dispersant for liquid medicine etc.
Ingredient(s): Vinylpyrrolidone Excipient
Dosage Form: Injectable / Parenteral, Tablet
Category: Solubilizers
Technical Specifications: Not Available
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Applications: Copovidone is used as a tablet binder, a film-former, & as part of the matrix material used in controlled-release formulations. It can be used as a binder for direct compression & wet granulation.
Ingredient(s): Copovidone K25-31
Dosage Form: Tablet
Category: Solubilizers
Technical Specifications: Not Available
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Applications: Non-Ionic Hydrophilic Surfactant, Emulsifier, Solubilizer
Ingredient(s): Polysorbate 20
Dosage Form: Capsule, Cream / Lotion / Ointment, Gel, Shampoo, Solution, Syrup, Tablet
Category: Solubilizers
Technical Specifications: HLB: 17, EO: 20; EXCiPACT
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Applications: Nonionic solubilizer, emulsifier and co-emulsifier
Ingredient(s): Polysorbate 20
Dosage Form: Gel, Softgel Capsule, Solution, Suppository
Category: Solubilizers
Technical Specifications: Not Available
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Applications: Polysorbate 80 acts as solubilizer, emulsifier and wetting agent.
Ingredient(s): Polysorbate 80
Dosage Form: Capsule, Suspension, Tablet
Category: Solubilizers
Technical Specifications: Not Available
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Applications: Nonionic solubilizer, emulsifier and co-emulsifier
Ingredient(s): Polysorbate 60
Dosage Form: Gel, Softgel Capsule, Solution, Suppository
Category: Solubilizers
Technical Specifications: Not Available
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Applications: Solubilizing agents and Stabilizers.
Ingredient(s): Beta-Cyclodextrin
Dosage Form: Tablet
Category: Solubilizers
Technical Specifications: Not Available
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Applications: Nonionic solubilizer, emulsifier and co-emulsifier
Ingredient(s): Polysorbate 80
Dosage Form: Gel, Softgel Capsule, Solution, Suppository
Category: Solubilizers
Technical Specifications: Not Available
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Applications: Poloxamer 188 provides better storage stability. It is used as solubilizers for liquid preparation & oral care products, matrix materials for ointment & gel.
Ingredient(s): Poloxamer 188
Dosage Form: Granule / Pellet, Tablet
Category: Solubilizers
Technical Specifications: Not Available
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