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Looking for solubilizer excipients? Find lipids, surfactants, cyclodextrins, organic liquids, etc. for bioavailability and solubility enhancement.

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Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

BASF

BioSpectra

Corel Pharma Chem

Gangwal Chemicals

Hayashibara

Huzhou Sunflower Pharmacetuical Co. Ltd

Microlex e.U

Nanjing Bold Chemical

PMC Isochem

Roquette

SPI Pharma

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Shanghai Shenmei Pharmaceutical Technology Co., Ltd

Shanghai Welltone Material Technology Co., Ltd

The Dow Chemical Company

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Applications: Vitamin E TPGS (Tocophersolan) is a multirole excipient for pharmaceutical drug delivery. It can be used as a solubilizer for poorly soluble drugs and as an emulsifying agent, plasticizer, stabilizer & vehicle for lipid based formulations.

Ingredient(s): Tocophersolan

Dosage Form: Capsule, Injectable / Parenteral, Ophthalmic Solution, Nasal Solution, Tablet

Category: Solubilizers

Route of Administration (Grade): Oral, Parenteral, Nasal, Ophthalmic, Topical
Pharmacopoeia Reference: USP 40 – NF 35

Technical Specifications: Specific Gravity: 1.06 at 50°C to 1.03 at 90°C; Solubility In Water: -20% at 20°C; Viscosity: 390cP at 50°C

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Applications: Advantose® 100 is a spray-dried maltose powder that provides excellent flow, solubility, & tableting properties to oral dosage forms. Maltose is well known for its safety & mouthfeel qualities, especially in chewable tablets & lozenges.

Ingredient(s): Maltose Sugar

Dosage Form: Tablet

Category: Solubilizers

Route of Administration (Grade): Oral
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications: Stabilizer, Cryoprotectant

Ingredient(s): Trehalose Dihydrate Excipient

Dosage Form: Injectable / Parenteral, Solution

Category: Solubilizers

Route of Administration (Grade): Injection, Ophthalmic
Pharmacopoeia Reference: USP-NF, JP, EP

Technical Specifications: Low endotoxin grade non-reducing disaccharide consisting of two glucose molecules linked by an alpha, alpha 1 bond.

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Applications: Diluent; It improves hardness & disintegration

Ingredient(s): Maltose Sugar

Dosage Form: Solution

Category: Solubilizers

Route of Administration (Grade): Solid Orals, Liquids, Injections
Pharmacopoeia Reference: USP-NF, JPE, Type IV DMF

Technical Specifications: Maltose is a reducing disaccharide consisting of two glucose molecules linked by an ?-1,4 bond.

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Applications: Binder, Film Coating, SR polymer, solubility enhancement, topical spreading agent

Ingredient(s): Hydroxypropyl Cellulose

Dosage Form: Capsule, Solution, Tablet

Category: Solubilizers

Route of Administration (Grade): Oral
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications: Polysorbate 80 in dry powder form

Ingredient(s): Magnesium aluminium silicate, Polysorbate 80

Dosage Form: Capsule, Tablet

Category: Solubilizers

Route of Administration (Grade): Solid Oral
Pharmacopoeia Reference: USP-NF / EP / JP & having US DMF

Technical Specifications: Solubilizer in powder form, used in directly compressible dosage forms, Wet granulation, added during lubrication stage

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Applications: Polyoxyl 40 hydrogenated castor oil In dry powder form

Ingredient(s): MAGNESIUM ALUMINOMETASILICATE, Polyoxyl 40 Hydrogenated Castor Oil

Dosage Form: Capsule, Tablet

Category: Solubilizers

Route of Administration (Grade): Oral
Pharmacopoeia Reference: USP-NF / EP / JP

Technical Specifications: Solubilizer in powder form, used in Directly compressible dosage forms, Wet granulation, added during lubrication stage

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Applications: Ethoxylated fatty acids; Polyoxyl 8 stearate; PEG 8 stearate PEG monostearate

Ingredient(s): Macrogol 8 Stearate

Dosage Form: Cream / Lotion / Ointment, Topical Film

Category: Solubilizers

Route of Administration (Grade): Topical
Pharmacopoeia Reference: USP-NF / EP

Technical Specifications: Emulsifying surfactant

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Applications: Guanidine Hydrochloride is a strong protein denaturant that functions as a chaotropic agent. As a denaturant, it acts to unfold proteins and turn them into their original polypeptide chains. it breaks down the structure of proteins.

Ingredient(s): Guanidine Hydrochloride

Dosage Form: Cream / Lotion / Ointment

Category: Solubilizers

Route of Administration (Grade): Topical
Pharmacopoeia Reference: Not Available

Technical Specifications: Bio Excipient Grade

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Applications: Sorbitan Esters / SPANs

Ingredient(s): Sorbitan Monostearate

Dosage Form: Cream / Lotion / Ointment, Emulsion, Injectable / Parenteral, Topical Film

Category: Solubilizers

Route of Administration (Grade): Solid oral, Liquid, Topical
Pharmacopoeia Reference: USP-NF / EP / JP

Technical Specifications: Non-Ionic Lipophilic surfactant; Emulsifier (w/o emulsions)

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Applications: Its applications include solubilizing proteins from inclusion bodies, increasing solubility of hydrophobic peptides and proteins and denaturing proteins. Urea may be used with guanidine hydrochloride in the refolding of denatured proteins.

Ingredient(s): Urea

Dosage Form: Cream / Lotion / Ointment

Category: Solubilizers

Route of Administration (Grade): Topical
Pharmacopoeia Reference: Not Available

Technical Specifications: Bio Excipient Grade

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Applications: Sorbitan Esters / SPANs

Ingredient(s): Sorbitan Monolaurate

Dosage Form: Cream / Lotion / Ointment, Emulsion, Injectable / Parenteral

Category: Solubilizers

Route of Administration (Grade): Solid Oral, Liquid, Topical
Pharmacopoeia Reference: USP-NF / EP / JP

Technical Specifications: Non-Ionic Lipophilic Surfactant; Emulsifier (w/o emulsions)

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Applications: Solubility enhancement, Spray-Dried Dispersion (SDD), Hot Melt Extrusion (HME)

Ingredient(s): Hydroxypropyl methylcellulose acetate succinate

Dosage Form: Tablet

Category: Solubilizers

Route of Administration (Grade): Not Available
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications: Solubility enhancement, Spray-Dried Dispersion (SDD), Hot Melt Extrusion (HME)

Ingredient(s): Hydroxypropyl Methylcellulose

Dosage Form: Tablet

Category: Solubilizers

Route of Administration (Grade): Not Available
Pharmacopoeia Reference: Not Available

Technical Specifications: Not Available

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Applications: Sorbitan Esters / SPANs

Ingredient(s): sorbitan oleate

Dosage Form: Cream / Lotion / Ointment, Emulsion, Injectable / Parenteral, Solution, Topical Film

Category: Solubilizers

Route of Administration (Grade): Solid oral, Liquid, Topical
Pharmacopoeia Reference: USP-NF / EP / JP

Technical Specifications: Non-Ionic Lipophilic surfactant; Emulsifier (w/o emulsions)

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Applications: Ethoxylated fatty acids; Polyoxyl 40 stearate; PEG 40 stearate

Ingredient(s): Macrogol 40 Stearate

Dosage Form: Cream / Lotion / Ointment, Topical Film

Category: Solubilizers

Route of Administration (Grade): Topical
Pharmacopoeia Reference: USP-NF / EP

Technical Specifications: Emulsifying Surfactant

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Applications: Chemical structure was rationally designed to maximize safety and optimize interaction to improve the solubility, stability, bio availability or lessen volatility, irritation, smell or taste.

Ingredient(s): Betadex Sulfobutyl Ether Sodium Excipient

Dosage Form: Injectable / Parenteral, Ophthalmic Solution, Nasal Solution, Topical Film

Category: Solubilizers

Route of Administration (Grade): Parenteral, Oral, Ophthalmic, Nasal, Topical, Oral and Inhalation.
Pharmacopoeia Reference: USP NF

Technical Specifications: Captisol® is a polyanionic beta-cyclodextrin derivative with a sodium sulfonate salt separated from the lipophilic cavity by a butyl ether spacer group, or sulfobutylether (SBE). Relative to beta-cyclodextrin, Captisol® provides higher interaction charact

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Applications: Enteric/ Delayed Release Matrix and Solubility Enhancement

Ingredient(s): Methacrylic Acid - Ethyl Acrylate Copolymer

Dosage Form: Capsule, Tablet

Category: Solubilizers

Route of Administration (Grade): Solid Oral
Pharmacopoeia Reference: Multicompendial

Technical Specifications: Methylacryli acid and Ethyl Acrylate copolymer (1:1) Type A

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Applications: Stabilization/Complexation/Taste masking/Encapsulation/Odour masking

Ingredient(s): Hydroxypropyl Betacyclodextrin

Dosage Form: Capsule, Ophthalmic Solution, Solution, Tablet

Category: Solubilizers

Route of Administration (Grade): Solid/Liquid Oral/Inj/Opthalmic
Pharmacopoeia Reference: USP-NF / Ph. Eur. / BP / IP

Technical Specifications: Not Available

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Applications: Kovidone- K series products posses excellent binding, film-forming, dispersing, and thickning properties and are widely used in the following dosage forms. BinderSolubilizerCoating agentSuspending, Stabilizing or viscocity modifying agent

Ingredient(s): Polyvinylpyrrolidone, Povidone

Dosage Form: Capsule, Tablet

Category: Solubilizers

Route of Administration (Grade): Solid Orals
Pharmacopoeia Reference: USP-NF/EP/BP/IP/JP/FCC

Technical Specifications: PVP K-K-30/ K-17/ K19/ K25/ K90