[{"orgOrder":0,"company":"Otovia Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Otolaryngology (Ear, Nose, Throat)","country":"","productType":"Undisclosed","year":"2023","type":"Inapplicable","leadProduct":"OTOV101N","moa":"Undisclosed","graph1":"Otolaryngology (Ear, Nose, Throat)","graph2":"Undisclosed","graph3":"Otovia Therapeutics","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Otolaryngology","amount2New":0,"dosageForm":"Intracochlear Injection","sponsorNew":"Otovia Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"1","companyTruncated":"Otovia Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Keep Hearing, Inc.","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Otolaryngology (Ear, Nose, Throat)","country":"","productType":"Dietary Supplement","year":"2024","type":"Inapplicable","leadProduct":"Acemg","moa":"Undisclosed","graph1":"Otolaryngology (Ear, Nose, Throat)","graph2":"Undisclosed","graph3":"Keep Hearing, Inc.","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Otolaryngology","amount2New":0,"dosageForm":"Oral Softgel Capsule","sponsorNew":"Keep Hearing, Inc. \/ Inapplicable","highestDevelopmentStatusID":"1","companyTruncated":"Keep Hearing, Inc. \/ Inapplicable"},{"orgOrder":0,"company":"Applied Biology","sponsor":"Safety Shot","pharmaFlowCategory":"DU","therapeuticArea":"Otolaryngology (Ear, Nose, Throat)","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Pimozide","moa":"Serotonin 2a (5-HT2a) receptor | Dopamine receptor","graph1":"Otolaryngology (Ear, Nose, Throat)","graph2":"Undisclosed","graph3":"Applied Biology","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Otolaryngology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Applied Biology \/ Jupiter Wellness","highestDevelopmentStatusID":"1","companyTruncated":"Applied Biology \/ Jupiter Wellness"},{"orgOrder":0,"company":"Safety Shot","sponsor":"Applied Biology","pharmaFlowCategory":"DU","therapeuticArea":"Otolaryngology (Ear, Nose, Throat)","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Inapplicable","leadProduct":"Pimozide","moa":"Serotonin 2a (5-HT2a) receptor | Dopamine receptor","graph1":"Otolaryngology (Ear, Nose, Throat)","graph2":"Undisclosed","graph3":"Safety Shot","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Otolaryngology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Safety Shot \/ Applied Biology","highestDevelopmentStatusID":"1","companyTruncated":"Safety Shot \/ Applied Biology"},{"orgOrder":0,"company":"University Hospital Antwerp","sponsor":"Royal DSM","pharmaFlowCategory":"DU","therapeuticArea":"Otolaryngology (Ear, Nose, Throat)","country":"","productType":"Probiotic","year":"2021","type":"Inapplicable","leadProduct":"Probiotic","moa":"Immune","graph1":"Otolaryngology (Ear, Nose, Throat)","graph2":"Undisclosed","graph3":"University Hospital Antwerp","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Otolaryngology","amount2New":0,"dosageForm":"Oral Tablet, Chewable","sponsorNew":"University Hospital Antwerp \/ Royal DSM","highestDevelopmentStatusID":"1","companyTruncated":"University Hospital Antwerp \/ Royal DSM"},{"orgOrder":0,"company":"NYU Langone Health","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Otolaryngology (Ear, Nose, Throat)","country":"U.S.A","productType":"Protein","year":"2023","type":"Inapplicable","leadProduct":"Creatine Monohydrate","moa":"Undisclosed","graph1":"Otolaryngology (Ear, Nose, Throat)","graph2":"Undisclosed","graph3":"NYU Langone Health","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Otolaryngology","amount2New":0,"dosageForm":"Oral Powder","sponsorNew":"NYU Langone Health \/ Inapplicable","highestDevelopmentStatusID":"1","companyTruncated":"NYU Langone Health \/ Inapplicable"},{"orgOrder":0,"company":"Ivano-Frankivsk National Medical University","sponsor":"Bionorica SE","pharmaFlowCategory":"DU","therapeuticArea":"Otolaryngology (Ear, Nose, Throat)","country":"","productType":"Plant Extract\/Herbal","year":"2020","type":"Inapplicable","leadProduct":"BNO 1030 Extract","moa":"Immune","graph1":"Otolaryngology (Ear, Nose, Throat)","graph2":"Undisclosed","graph3":"Ivano-Frankivsk National Medical University","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Otolaryngology","amount2New":0,"dosageForm":"Oral Solution","sponsorNew":"Ivano-Frankivsk National Medical University \/ Bionorica SE","highestDevelopmentStatusID":"1","companyTruncated":"Ivano-Frankivsk National Medical University \/ Bionorica SE"},{"orgOrder":0,"company":"Pediatrica S.r.l","sponsor":"Tigermed","pharmaFlowCategory":"DU","therapeuticArea":"Otolaryngology (Ear, Nose, Throat)","country":"","productType":"Dietary Supplement","year":"2021","type":"Inapplicable","leadProduct":"Pediafl\u00f9","moa":"Undisclosed","graph1":"Otolaryngology (Ear, Nose, Throat)","graph2":"Undisclosed","graph3":"Pediatrica S.r.l","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Otolaryngology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Pediatrica S.r.l \/ Tigermed","highestDevelopmentStatusID":"1","companyTruncated":"Pediatrica S.r.l \/ Tigermed"},{"orgOrder":0,"company":"University Hospital Sestre Milosrdnice","sponsor":"JGL d.d","pharmaFlowCategory":"DU","therapeuticArea":"Otolaryngology (Ear, Nose, Throat)","country":"","productType":"Dietary Supplement","year":"2023","type":"Inapplicable","leadProduct":"Nasal Irrigation With Seawater Isotonic Solution","moa":"Undisclosed","graph1":"Otolaryngology (Ear, Nose, Throat)","graph2":"Undisclosed","graph3":"University Hospital Sestre Milosrdnice","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Otolaryngology","amount2New":0,"dosageForm":"Nasal Spray","sponsorNew":"University Hospital Sestre Milosrdnice \/ Jadran Galenski laboratorij","highestDevelopmentStatusID":"1","companyTruncated":"University Hospital Sestre Milosrdnice \/ Jadran Galenski laboratorij"},{"orgOrder":0,"company":"Hospital de Matar\u00f3","sponsor":"Nutricia Inc","pharmaFlowCategory":"DU","therapeuticArea":"Otolaryngology (Ear, Nose, Throat)","country":"","productType":"Undisclosed","year":"2024","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Otolaryngology (Ear, Nose, Throat)","graph2":"Undisclosed","graph3":"Hospital de Matar\u00f3","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Otolaryngology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Hospital de Matar\u00f3 \/ Nutricia Inc","highestDevelopmentStatusID":"1","companyTruncated":"Hospital de Matar\u00f3 \/ Nutricia Inc"},{"orgOrder":0,"company":"Cochlear","sponsor":"University of Iowa | LWB Consulting | Althea Anagnostopoulos Harrington | MV Clinical Research","pharmaFlowCategory":"DU","therapeuticArea":"Otolaryngology (Ear, Nose, Throat)","country":"","productType":"Steroid","year":"2024","type":"Inapplicable","leadProduct":"Dexamethasone","moa":"Glucocorticoid receptor","graph1":"Otolaryngology (Ear, Nose, Throat)","graph2":"Undisclosed","graph3":"Cochlear","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Otolaryngology","amount2New":0,"dosageForm":"Implant","sponsorNew":"Cochlear \/ University of Iowa | LWB Consulting | Althea Anagnostopoulos Harrington | MV Clinical Research","highestDevelopmentStatusID":"1","companyTruncated":"Cochlear \/ University of Iowa | LWB Consulting | Althea Anagnostopoulos Harrington | MV Clinical Research"},{"orgOrder":0,"company":"NYU Langone Health","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Otolaryngology (Ear, Nose, Throat)","country":"U.S.A","productType":"Protein","year":"2024","type":"Inapplicable","leadProduct":"Protein","moa":"Protein","graph1":"Otolaryngology (Ear, Nose, Throat)","graph2":"Undisclosed","graph3":"NYU Langone Health","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Otolaryngology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"NYU Langone Health \/ Inapplicable","highestDevelopmentStatusID":"1","companyTruncated":"NYU Langone Health \/ Inapplicable"},{"orgOrder":0,"company":"Nestle Health Sciences SA","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Otolaryngology (Ear, Nose, Throat)","country":"SWITZERLAND","productType":"Undisclosed","year":"2021","type":"Inapplicable","leadProduct":"Thickenup Gel Express","moa":"Undisclosed","graph1":"Otolaryngology (Ear, Nose, Throat)","graph2":"Undisclosed","graph3":"Nestle Health Sciences SA","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Otolaryngology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Nestle Health Sciences SA \/ Inapplicable","highestDevelopmentStatusID":"1","companyTruncated":"Nestle Health Sciences SA \/ Inapplicable"},{"orgOrder":0,"company":"CEN Biotech","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Otolaryngology (Ear, Nose, Throat)","country":"","productType":"Plant Extract\/Herbal","year":"2022","type":"Inapplicable","leadProduct":"Plant Extract","moa":"Undisclosed","graph1":"Otolaryngology (Ear, Nose, Throat)","graph2":"Undisclosed","graph3":"CEN Biotech","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Otolaryngology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"CEN Biotech \/ Inapplicable","highestDevelopmentStatusID":"1","companyTruncated":"CEN Biotech \/ Inapplicable"},{"orgOrder":0,"company":"St. Jude Children","sponsor":"Blue Water Vaccines","pharmaFlowCategory":"D","therapeuticArea":"Otolaryngology (Ear, Nose, Throat)","country":"U.S.A","productType":"Vaccine","year":"2020","type":"Licensing Agreement","leadProduct":"Streptococcus Pneumoniae Vaccine","moa":"Undisclosed","graph1":"Otolaryngology (Ear, Nose, Throat)","graph2":"Undisclosed","graph3":"St. Jude Children","amount2":0,"highestDevelopmentShortName":"Undisclosed","therapeuticAreaShortName":"Otolaryngology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"St. Jude Children \/ Blue Water Vaccines","highestDevelopmentStatusID":"1","companyTruncated":"St. Jude Children \/ Blue Water Vaccines"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          Cochlear

                          Country arrow
                          Pharmaconex
                          Not Confirmed

                          Cochlear

                          Country arrow
                          Pharmaconex
                          Not Confirmed

                          Lead Product(s) : Dexamethasone

                          Therapeutic Area : Otolaryngology (Ear, Nose, Throat)

                          Study Phase : Undisclosed

                          Sponsor : University of Iowa | LWB Consulting | Althea Anagnostopoulos Harrington | MV Clinical Research

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Steroid

                          Upfront Cash : Inapplicable

                          September 19, 2024

                          Lead Product(s) : Dexamethasone

                          Therapeutic Area : Otolaryngology (Ear, Nose, Throat)

                          Highest Development Status : Undisclosed

                          Sponsor : University of Iowa | LWB Consulting | Althea Anagnostopoulos Harrington | MV Clinical Research

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Pharmaconex
                          Not Confirmed
                          Pharmaconex
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          July 25, 2024

                          Lead Product(s) : Protein

                          Therapeutic Area : Otolaryngology (Ear, Nose, Throat)

                          Highest Development Status : Undisclosed

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Keep Hearing, Inc.

                          Country arrow
                          Process Development
                          Not Confirmed

                          Keep Hearing, Inc.

                          Country arrow
                          Process Development
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Dietary Supplement

                          Upfront Cash : Inapplicable

                          June 27, 2024

                          Lead Product(s) : Acemg

                          Therapeutic Area : Otolaryngology (Ear, Nose, Throat)

                          Highest Development Status : Undisclosed

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Hospital de Mataró

                          Country arrow
                          Pharmaconex
                          Not Confirmed

                          Hospital de Mataró

                          Country arrow
                          Pharmaconex
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          February 09, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Otolaryngology (Ear, Nose, Throat)

                          Highest Development Status : Undisclosed

                          Sponsor : Nutricia Inc

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          University Hospital Sestre Milosrdnice

                          Country arrow
                          Pharmaconex
                          Not Confirmed

                          University Hospital Sestre Milosrdnice

                          Country arrow
                          Pharmaconex
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Dietary Supplement

                          Upfront Cash : Inapplicable

                          July 17, 2023

                          Lead Product(s) : Nasal Irrigation With Seawater Isotonic Solution

                          Therapeutic Area : Otolaryngology (Ear, Nose, Throat)

                          Highest Development Status : Undisclosed

                          Sponsor : JGL d.d

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Otovia Therapeutics

                          Country arrow
                          Process Development
                          Not Confirmed

                          Otovia Therapeutics

                          Country arrow
                          Process Development
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          June 13, 2023

                          Lead Product(s) : OTOV101N

                          Therapeutic Area : Otolaryngology (Ear, Nose, Throat)

                          Highest Development Status : Undisclosed

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Pharmaconex
                          Not Confirmed
                          Pharmaconex
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          May 12, 2023

                          Lead Product(s) : Creatine Monohydrate

                          Therapeutic Area : Otolaryngology (Ear, Nose, Throat)

                          Highest Development Status : Undisclosed

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Pharmaconex
                          Not Confirmed
                          Pharmaconex
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          August 19, 2022

                          Lead Product(s) : Pimozide

                          Therapeutic Area : Otolaryngology (Ear, Nose, Throat)

                          Highest Development Status : Undisclosed

                          Sponsor : Safety Shot

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Pharmaconex
                          Not Confirmed
                          Pharmaconex
                          Not Confirmed

                          Details : This study aims to investigate if the dopamine receptor antagonist Pimozide can be used effectively treat COVID-19 for tinnitus, emergent symptoms lasting longer than 4 weeks since onset.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          June 10, 2022

                          Lead Product(s) : Pimozide

                          Therapeutic Area : Otolaryngology (Ear, Nose, Throat)

                          Highest Development Status : Undisclosed

                          Sponsor : Applied Biology

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          CEN Biotech

                          Country arrow
                          Pharmaconex
                          Not Confirmed

                          CEN Biotech

                          Country arrow
                          Pharmaconex
                          Not Confirmed

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : Inapplicable

                          March 29, 2022

                          Lead Product(s) : Plant Extract

                          Therapeutic Area : Otolaryngology (Ear, Nose, Throat)

                          Highest Development Status : Undisclosed

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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