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Find Drugs for Trauma (Emergency, Injury, Surgery) in Preclinical Development

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            Lead Product(s): ST266

            Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: ST266

            Highest Development Status: Preclinical Product Type: Cell and Gene therapy

            Partner/Sponsor/Collaborator: Walter Reed Army Institute

            Deal Size: Undisclosed Upfront Cash: Undisclosed

            Deal Type: Collaboration February 01, 2021

            Details:

            The TBI models will utilize targeted intranasal nose-to-brain administration of ST266. The ultimate goals are to advance ST266 into human clinical trials of targeted intranasal administration for TBI.

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            Lead Product(s): Mosedipimod

            Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: EC-18

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: NASA

            Deal Size: $0.1 million Upfront Cash: Undisclosed

            Deal Type: Funding January 26, 2021

            Details:

            NASA’s Human Research Program has awarded $150K in grant funding to conduct research on its lead compound EC-18, and how it impacts astronaut health and performance during future long-duration missions beyond low-Earth orbit.

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            Lead Product(s): Tipelukast

            Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: MN-001

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: National Institute of General Medical Sciences

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable November 12, 2020

            Details:

            The study sought to examine the pathogenic role of phosphodiesterase 4 (PDE4) in hepatic stellate cell (HSC) activation and TGFβ1 (transforming growth factor beta 1) signaling. TGFβ1 induced HSC activation.

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            Lead Product(s): BP-C2

            Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: BP-C2

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable October 19, 2020

            Details:

            BP-C2 reduces mortality when administered 24 hours post-exposure in a murine model of severe, radiation-induced gastrointestinal acute radiation syndrome (GI-ARS).

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            Lead Product(s): CX717

            Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: CX717

            Highest Development Status: Preclinical Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable October 06, 2020

            Details:

            Studies describes the ability of CX717, one of the Company’s lead ampakines, to improve motor nerve function in an animal