loader
Please Wait
Applying Filters...
Promoted Content
Promoted Content

Market Place

Market Place

Market Place

Menu

Post Enquiry

Post Enquiry

PharmaCompass

Home

Market Place

Market Place

Search
All
API
FDF
Price
Services
Excipients
Enquiries

    Find

    • Active Pharmaceutical Ingredients Active Pharmaceutical Ingredients
    • Finished Drug Formulations Finished Drug Formulations
    • Price Price
    • Excipients Excipients
    • Services Services
    • Market Place Marketplace

    Market Place

    Market Place

    Post Enquiry

    Post Enquiry

    Disintegration testers are pharmaceutical apparatus used to record the time it takes a sample to dissolve in a beaker of test media. Specifically, disintegration testers record the moment the sample breaks down from its original form into one that can then become a solute with the test media. Disintegration units are used by QC and research laboratories to confirm that tablets breakdown within a required, uniform amount of time, which can aid in compliance and development studies. Disintegration testing determines whether tablets or capsules disintegrate within a defined period of time when placed in a liquid medium. Disintegration testers as required by current Pharmacopeia should be able to provide a reproducible and standardized method of ensuring that disintegration has taken place. In automatic tablet disintegration testing, the disintegration time including disintegration characteristics is recorded automatically. The primary purpose of disintegration testers is to measure the amount of time it takes a sample to totally disintegrate inside a liquid medium. The liquid used in the disintegration tester vessel is often an acidic mixture, designed to replicate the inside of the human stomach. Disintegration testers allow researchers and quality control technicians to ascertain if a sample does indeed breakdown inside the human body, and how long it takes to do so. This can provide information useful to improving and manufacturing pharmaceutical drugs and also confirm that standards of compliance and regulation are being maintained. Disintegration testers work by raising and lowering a ‘basket’ in and out of the test medium, for a set period of time, to see if the tablet dissolves or not. The test medium sits inside the vessel, which sits inside a bath of warmed water, used to replicate the temperature of the human body. The disintegration testers raise and lower the basket in an attempt to create movement, similar to the conditions indie the human stomach, so that the tablet can move about and the test medium circulate around it in a manner similar to inside the body. At no point does the basket raise itself completely out of the test medium, so the tablet is always submerged throughout the disintegration tester’s operation. Disintegration testers are commonly comprised of a basket, a vessel, a water bath and the actual disintegration unit itself (which operates the basket motion and heats and pumps the water in the bath). Traditionally, disintegration testers required a laboratory technician to manually lower the basket into the vessel before the test commenced. It was also common place to have to manually set the teste time, then visually remove and inspect the basket, to see if the tablet had dissolved. In recent years, automation has become increasingly more desirable, whereby disintegration testers can automatically lower and raise their own baskets into the medium, and in some cases, even determine the exact time of tablet disintegration too. Disintegration testers are an effective analytical solution for the testing of fast release, oral tablets which require short assessment times. There are times when tablets are required to dissolve quickly in the mouth, and on occasion release their API before reaching the human stomach tract. This can present a few challenges when attempting to perform accurate in vitro testing, such emulating the environment of the human mouth and taking samples very quickly after the tablet has be submersed into the media. Disintegration testers can offer a solution to this problem where other lab equipment can struggle. USP 4 systems are more adept for long term, slow release testing, and dissolution apparatus does not always offer the correct vessel and paddle size required when considering the human mouth has just 5mm of liquid within it. Taking fast samples in a short amount of time from these methods is also a little tricky. Disintegration testers on the other hand, have a slightly more assessable media vessel, and can function with a lower volume of test media inside them, allowing for a more accurate testing environment, where fast testing can be more easily performed. A test of just 2 minutes, with several sample extractions can be performed in lower media volumes. This makes disintegration testers the preferred option for testing fast release oral samples. It will be very interesting to see how USP continues to adapt and develop protocol to account for the testing of orally releasing samples. Disintegration testers (like most other lab equipment) provide useful, important information that is used in compliance, manufacturing and R&D departments throughout pharmaceutical and research organisations. It is of course the test results themselves that contain this all-important material, but what can you do to protect and preserve both the disintegration testers and their test result’s integrity and safety? Taking back up your test results is a proven method of data security, even in the face of theft or machine destruction. Backing up test results from all your disintegration testers is easy, simple and a real life saver should anything ever go wrong. Export your test results similar to backing up, exporting your test results at the end of every test, directly from the disintegration testers to a computer or memory stick saves you the trouble of having to remember to back up in the first place. Backup your disintegration tester’s settings a fantastic way to safeguard yourself in the event of a fire, serious breakdown or theft. The ability to export everything from one machine and re-install it on another is a must have capability. You can export settings, user accounts, methods, products and more with ease between all of your disintegration testers. User logging: a practically faultless trail of what every user does on the machine, from first logging in, to running tests, printing, exporting, adding products and logging out. You will always know who has done what and on which disintegration testers they have done it. User accounts: the best way to restrict user access to certain tasks and areas, while having an administrator account capable of doing and monitoring everything else also adds an extra layer of security and integrity. Many analytical testing service providers have disintegration testers with the above mentioned capabilities. The next stage of evolution in the field of disintegration testers has arrived having features including a built-in touch-screen display, capable of storing product test results, methods and basket configurations, along with calibration parameters and user login accounts, automatically recording and determining the disintegration time of the sample without human participation, making such disintegration testers truly advanced. The disintegration tester comes with either one or two individually driven basket rack assemblies as well, offering flexibility and staggered testing possibilities. When it comes to disintegration, there are generally only two varieties of testers to choose from – manual, and automatic. Manual disintegration testers require a lab technician to lower and raise the test station into the test media, and start the programed timer. When the testing is complete, the technician then rises the tests station and visually inspects to see if disintegration has occurred. Automated disintegration testers automatically lower and raise the test station can start the timer without human intervention, and some can then determine the exact point of disintegration during the test too. When the timer is expired, the test station then raises of its own accord. Most manufacturers of disintegration testers offer between 1 and 4 test stations per machine, and you can have a choice between two types of basket to contain the samples as well. Each basket type can contain either 6, or 3 samples, of different sizes.

    Proveris-Wallpaper
    Proveris-Wallpaper
    Previous
    Next
    Filters Filter
    ×
    FILTER DATA :

    filter

    Arbro Pharmaceuticals Pvt. Ltd

    Basic Pharma

    Cebiphar

    Curtis Health Caps

    GVK Biosciences

    Merck Millipore

    QUINTA-ANALYTICA s.r.o

    RD Laboratories

    Softigel Procaps

    Vitas Analytical Services

    filter

    COLOMBIA

    CZECH REPUBLIC

    FRANCE

    INDIA

    NORWAY

    Netherlands

    POLAND

    UNITED STATES

    Softigel Procaps

    • FDA
    • EDQM

    Virtual BoothA leading provider of Contract Development and Manufacturing services in softgel advanced technologies for the global market.

    COLOMBIA Colombia

    Contact Supplier Contact Supplier

    Virtual Booth Virtual Booth

    Interphex Week Tokyo

    Participation Not Confirmed

    Update your events

    Disintegration Studies

    Supporting Information: Click here to upload a PDF
    Link Icon Link to Supplier Content
    Contact the Supplier
    Softigel-Disintegration-Studies

    - Service Details

    Our analytical instrumentation capabilities include DSC, MDSC & TGA capabilities, automated dissolution system, HPLC with UV, PDA, FL, RI Detectors, Gas chromatography, Disintegration studies, infrared apparatus among others.

    - Directory Listing

    Pharma Service: Analytical

    Category: Analytical Testing Services

    Sub Category: Disintegration

    QUINTA-ANALYTICA s.r.o

    • FDA
    • EDQM

    Virtual BoothGlobal provider of comprehensive top services in the field of Drug Testing, Clinical Trials & Bioanalytical Services.

    CZECH REPUBLIC Czech Republic

    Contact Supplier Contact Supplier

    Virtual Booth Virtual Booth

    Interphex Week Tokyo

    Participation Not Confirmed

    Update your events

    Disintegrator - VanKel

    Supporting Information: Click here to upload a PDF
    Link Icon Link to Supplier Content
    Contact the Supplier

    - Service Details

    Quinta is an established provider of multiple R&D and regulatory services for pharmaceutical, biotechnology and generic drug industries. Quinta holds GMP, GLP and GCP certificates.

    - Directory Listing

    Pharma Service: Analytical

    Category: Analytical Testing Services

    Sub Category: Disintegration

    RD Laboratories

      Virtual Booth Upgrade this company profile, update & customize all content// Ask PharmaCompass, click HERE

      UNITED STATES United States

      Contact Supplier Post An Enquiry

      Virtual Booth Virtual Booth

      Interphex Week Tokyo

      Participation Not Confirmed

      Update your events

      Disintegration Test For Finished Formulations

      Supporting Information: Click here to upload a PDF
      Link Icon Link to Supplier Content
      Contact the Supplier

      - Service Details

      R.D. Laboratories maintains a large array of analytical instrumentation capable of performing a wide variety of procedures.

      - Directory Listing

      Pharma Service: Analytical

      Category: Analytical Testing Services

      Sub Category: Disintegration

      Arbro Pharmaceuticals Pvt. Ltd

        Virtual Booth Upgrade this company profile, update & customize all content// Ask PharmaCompass, click HERE

        INDIA India

        Contact Supplier Post An Enquiry

        Virtual Booth Virtual Booth

        Interphex Week Tokyo

        Participation Not Confirmed

        Update your events

        Disintegration Testing

        Supporting Information: Click here to upload a PDF
        Link Icon Link to Supplier Content
        Contact the Supplier

        - Service Details

        Our pharmaceutical testing laboratory has been performing third-party testing of pharmaceutical finished products since the year 1990. We offer a complete package of pharmaceutical testing services for finished products for both the domestic as well as export markets.

        - Directory Listing

        Pharma Service: Analytical

        Category: Analytical Testing Services

        Sub Category: Disintegration

        Vitas Analytical Services

          Virtual Booth Upgrade this company profile, update & customize all content// Ask PharmaCompass, click HERE

          NORWAY Norway

          Contact Supplier Post An Enquiry

          Virtual Booth Virtual Booth

          Interphex Week Tokyo

          Participation Not Confirmed

          Update your events

          Disintegration Systems For Drug Products

          Supporting Information: Click here to upload a PDF
          Link Icon Link to Supplier Content
          Contact the Supplier

          - Service Details

          Our laboratories, equipped with the most modern instrumentation is operated by a well trained and highly motivated staff with an average of over 10 years of practical experience. The Pharmaceutical Analytical Laboratory is GMP inspected and under control of the respective authorities.

          - Directory Listing

          Pharma Service: Analytical

          Category: Analytical Testing Services

          Sub Category: Disintegration

          Merck Millipore

            Virtual Booth Upgrade this company profile, update & customize all content// Ask PharmaCompass, click HERE

            UNITED STATES United States

            Contact Supplier Post An Enquiry

            Virtual Booth Virtual Booth

            Interphex Week Tokyo

            Participation Not Confirmed

            Update your events

            Disintegration Test on Drug Products

            Supporting Information: Click here to upload a PDF
            Link Icon Link to Supplier Content
            Contact the Supplier

            - Service Details

            Our services include the development & validation of analytical methods. We identify by-products and determine polymorphic product forms's broad portfolio of analytical methods includes HPLC(-MS), CE, GC(-MS), FT-IR, NMR, particle size determination etc.

            - Directory Listing

            Pharma Service: Analytical

            Category: Analytical Testing Services

            Sub Category: Disintegration

            Curtis Health Caps

              Virtual Booth Upgrade this company profile, update & customize all content// Ask PharmaCompass, click HERE

              POLAND Poland

              Contact Supplier Post An Enquiry

              Virtual Booth Virtual Booth

              Interphex Week Tokyo

              Participation Not Confirmed

              Update your events

              Disintegration Time Study

              Supporting Information: Click here to upload a PDF
              Link Icon Link to Supplier Content
              Contact the Supplier

              - Service Details

              Curtis offers a wide range of analytical testing for raw materials & products such as disintegration time study, release profile study, determination of hardness, impurities (heavy metals, residual solvents), dyes, viscosity, preservatives & antioxidants.

              - Directory Listing

              Pharma Service: Analytical

              Category: Analytical Testing Services

              Sub Category: Disintegration

              Basic Pharma

                Virtual Booth Upgrade this company profile, update & customize all content// Ask PharmaCompass, click HERE

                Netherlands Netherlands

                Contact Supplier Post An Enquiry

                Virtual Booth Virtual Booth

                Interphex Week Tokyo

                Participation Not Confirmed

                Update your events

                Disintegration

                Supporting Information: Click here to upload a PDF
                Link Icon Link to Supplier Content
                Contact the Supplier

                - Service Details

                Basic Pharma Laboratory offers an extensive range of test methods at competitive prices.

                - Directory Listing

                Pharma Service: Analytical

                Category: Analytical Testing Services

                Sub Category: Disintegration

                GVK Biosciences

                • FDA
                • EDQM

                Virtual Booth Upgrade this company profile, update & customize all content// Ask PharmaCompass, click HERE

                INDIA India

                Contact Supplier Post An Enquiry

                Virtual Booth Virtual Booth

                Interphex Week Tokyo

                Participation Not Confirmed

                Update your events

                Disintegration Test Apparatus

                Supporting Information: Click here to upload a PDF
                Link Icon Link to Supplier Content
                Contact the Supplier

                - Service Details

                GVK BIO offers a broad range of analytical services for complex research needs. We perform method development, validate and transfer Good Manufacturing Practice (cGMP) compliant methods for a broad spectrum of pharma compounds.

                - Directory Listing

                Pharma Service: Analytical

                Category: Analytical Testing Services

                Sub Category: Disintegration

                Cebiphar

                • FDA
                • EDQM
                • Audit Compliance

                Virtual Booth Upgrade this company profile, update & customize all content// Ask PharmaCompass, click HERE

                FRANCE France

                Contact Supplier Post An Enquiry

                Virtual Booth Virtual Booth

                Interphex Week Tokyo

                Participation Not Confirmed

                Update your events

                Disintegration

                Supporting Information: Click here to upload a PDF
                Link Icon Link to Supplier Content
                Contact the Supplier

                - Service Details

                Cebiphar offers its expertise and technical platform to the pharmaceutical industry. At Cebiphar we provide physicochemical, pharmacotechnical & microbiological testings according to GMP quality standards.

                - Directory Listing

                Pharma Service: Analytical

                Category: Analytical Testing Services

                Sub Category: Disintegration

                PharmaCompass >>

                First
                Previous
                Next
                Last

                Market Place

                Market Place

                PharmaCompass

                Home

                Market Place

                Menu

                Post Enquiry

                Post Enquiry

                Market Place

                Market Place

                Search