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Arbor Biotechnologies, Inc

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Vertex and Arbor Biotechnologies Establish New Partnership to Develop Novel Ex Vivo Engineered Cell Therapies

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Under this new partnership, Vertex will receive rights to use Arbor’s technology to research and develop ex vivo engineered cell therapies towards Vertex’s goal of generating fully differentiated, insulin-producing hypoimmune islet cells for the treatment of type 1 diabetes.

Lead Product(s): Ex-vivo Engineered Cell Therapies

Therapeutic Area: Endocrinology Product Name: Undisclosed

Highest Development Status: Discovery Platform Product Type: Cell and Gene therapy

Partner/Sponsor/Collaborator: Vertex Pharmaceuticals

Deal Size: $1,200.0 million Upfront Cash: Undisclosed

Deal Type: Collaboration August 24, 2021

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Mina Therapeutics

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MiNA Therapeutics Announces Equity Investment from Lilly

Details:

Proceeds from the equity investment will be used to advance and expand MiNA’s internal pipeline of saRNA therapeutics, which is initially focused on immuno-oncology and genetic diseases.

Lead Product(s): RNA-based Medicines

Therapeutic Area: Endocrinology Product Name: Undisclosed

Highest Development Status: Discovery Platform Product Type: Large molecule

Partner/Sponsor/Collaborator: Eli Lilly

Deal Size: $15.0 million Upfront Cash: Undisclosed

Deal Type: Agreement July 06, 2021

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Mina Therapeutics

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Lilly and MiNA Therapeutics Announce saRNA Research Collaboration

Details:

MiNA will utilize its saRNA platform to research up to five targets selected by Lilly that aim to address diseases across Lilly’s key therapeutic focus areas. Lilly will conduct preclinical and clinical activities of candidates and will retain commercialization rights.

Lead Product(s): RNA-based medicines

Therapeutic Area: Endocrinology Product Name: Undisclosed

Highest Development Status: Discovery Platform Product Type: Large molecule

Partner/Sponsor/Collaborator: Eli Lilly

Deal Size: $1,250.0 million Upfront Cash: $25.0 million

Deal Type: Collaboration May 11, 2021

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Biolojic Design

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Lilly and Biolojic Design Announce Research Collaboration to Discover and Develop Antibody Therapies for Diabetes

Details:

The research collaboration and license agreement that will leverage Biolojic's AI-based multibody platform to discover and develop a potential novel antibody-based therapy for the treatment of diabetes.

Lead Product(s): Antibody-based therapy

Therapeutic Area: Endocrinology Product Name: Undisclosed

Highest Development Status: Discovery Platform Product Type: Large molecule

Partner/Sponsor/Collaborator: Eli Lilly

Deal Size: $121.0 million Upfront Cash: Undisclosed

Deal Type: Collaboration March 08, 2021

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