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Cryogenic Reactions at -70°C at 3000 L Scale 
API Manufacturing >> Low Temperature / Cryogenic conditions >> Overview
We offer cGMP custom manufacturing cryogenic reaction at -70°C at 3000L scale. This industrial capability combined with know-how in organometallic chemistry & asymmetric reactions is a valuable tool into the multistep synthesis industrial platform.
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Low Temperature Capabilities (Up to -80°C)
API Manufacturing >> Low Temperature / Cryogenic conditions >> Overview
Minakem High Potent (MHP), a recognized world leader custom manufacturer for development and commercialization of Highly Potent APIs (HAPI), offers low temperature capabilities (up to -80°C).
Temperature Capabilities From -100°C to +170°C
API Manufacturing >> Low Temperature / Cryogenic conditions >> Overview
Biondustria L.I.M has temperature capabilities from -100°C to +170°C.
Cryogenic Reaction Capabilities
API Manufacturing >> Low Temperature / Cryogenic conditions >> Overview
We are a specialized Pharma company focusing on the niche therapeutic areas of CNS, ARVs andnControlled substances having tremendous future growth potential. By virtue of this niche focus we have registered an impressivengrowth over the years.
Low Temperature Reactions Capabilities
API Manufacturing >> Low Temperature / Cryogenic conditions >> Overview
In addition to the classical chemical reactions, MINAKEM has developed a strong expertise in field of low temperature reactions at an industrial scale.
Low Temperature Asymmetric Synthesis
API Manufacturing >> Low Temperature / Cryogenic conditions >> Overview
ScinoPharm's core competency will be to specialize in producing international cGMP-quality Active Pharmaceutical Ingredients through organic synthesis.
Temperature Range from -80°C to +250 °C
API Manufacturing >> Low Temperature / Cryogenic conditions >> Overview
Large-scale production capacities (upto 4’500 L, with a temperature range from -80°C to +250 °C) allow the efficient production of early-phase APIs and large-scale intermediates under nonGMP conditions at the CARBOGEN AMCIS Swiss’ facilities.
Performing a Variability of Reactions (-50°C)
API Manufacturing >> Low Temperature / Cryogenic conditions >> Overview
Alven's facility has all relevant infrastructure to perform a variability of reactions and production conditions, including Temperature range -50 °C to 200 °C.
Low-Temperature Processes
API Manufacturing >> Low Temperature / Cryogenic conditions >> Overview
DOTTIKON has know-how and low-temperature equipment (glass and Hastelloy) on all scales for batch-wise as well as continuous processing: Research & Development up to 0.5 l and down to –80 °C, Small-scale & Pilot up to 160 l and down to –80 °C, Production
Expertise in Handling Cryogenic Reactions
API Manufacturing >> Low Temperature / Cryogenic conditions >> Overview
The company has expertise in handling cryogenic reactions and can perform cross-coupling reactions and carbonylation reactions on a large scale