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Improved Performance of Poorly Soluble Drugs

API/FDF Drug Development >> Preformulation & Material Science >> Solubility Assessment & Enhancement

With over 40% of new drug substances exhibiting poor aqueous solubility, a major task for industrial pharmaceutical scientists has been to explore alternative procedures for overcoming this characteristic which can compromise the bioavailability, and thereby detract from optimising the clinical

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Solubility Assessments

API/FDF Drug Development >> Preformulation & Material Science >> Solubility Assessment & Enhancement

Cebiphar, French CRO member of TERANGA Group (100 employees), offers its preformulation studies for formulation development. Cebiphar’s sustained commitment to quality enables the performance of studies according to GMP, GLP and GCP quality standards.

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Solubility Assessments

API/FDF Drug Development >> Preformulation & Material Science >> Solubility Assessment & Enhancement

Custom’s expert chemists, scientists and process engineers — many with 35 years of experience in the pharmaceutical industry — offer an extensive range of clinical and product development expertise, including significant preformulation and formulation exp

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Improvement of Bioavailability

API/FDF Drug Development >> Preformulation & Material Science >> Solubility Assessment & Enhancement

Glatt can optimize the active substance release and bioavailability by specific optimized formulation and process methods depending on the physico-chemical property of the active substance.

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Micropx™- Micro Pelletizing Technology

API/FDF Drug Development >> Preformulation & Material Science >> Solubility Assessment & Enhancement

The Glatt MicroPX™ technology (micro pelletizing technology) is a continuous fluidized bed agglomeration procedure for the manufacture of pellets and micropellets with a very high active ingredient content.

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Formulplex®

API/FDF Drug Development >> Preformulation & Material Science >> Solubility Assessment & Enhancement

It is a complexation process to improve the solubility and bioavailability of a poorly soluble active ingredient, This complexation process by cyclodextrins differs from other complexation processes. It is performed in supercritical CO2 medium.

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Evaluation of Solubility in Various Matrices-pH-Solubility

API/FDF Drug Development >> Preformulation & Material Science >> Solubility Assessment & Enhancement

GRAM Laboratories offers services for conduct of preformulation studies. These studies are physical and chemical characteristics of the active ingredient of pH-solubility-stability profile, evaluation of solubility in various matrices and moisture uptake studies-hygroscopicity.

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Solubility-Enhanced Dosage Forms Development

API/FDF Drug Development >> Preformulation & Material Science >> Solubility Assessment & Enhancement

With nearly 30 years of experience, Quotient has established a broad suite of technologies and formulation approaches to address these complex solubility challenges. Our approach allows us to dramatically speed up the optimization of your drug products to improve oral bioavailability.

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Lipidic Vehicles Development

API/FDF Drug Development >> Preformulation & Material Science >> Solubility Assessment & Enhancement

With nearly 30 years of experience, Quotient has established a broad suite of technologies and formulation approaches to address these complex solubility challenges. Our approach allows us to dramatically speed up the optimization of your drug products to improve oral bioavailability.

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