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Quotient Sciences has a proven track record of developing and manufacturing SDDs to overcome your poor drug solubility and delivery challenges. We tailor the development of your SDD toward the specific physical and biopharmaceutics properties.
With nearly 30 years of experience, Quotient has established a broad suite of technologies and formulation approaches including amorphous dispersions and lipidic formulation development.
Characterization studies for your product can be conducted prior to formulation. We specialize in the design and execution of pertinent pre-formulation activities required for successful pharmaceutical product development.
Comprehensive evaluation of drug candidates during pre-formulation is critical to the formulation development process. Specific challenges include low bioavailability, poor solubility and/or permeability, and poor physical stability.
It is a complexation process to improve the solubility and bioavailability of a poorly soluble active ingredient, This complexation process by cyclodextrins differs from other complexation processes. It is performed in supercritical CO2 medium.