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Chicago \/ La Jolla Pharmaceutical"},{"orgOrder":0,"company":"Northwestern University","sponsor":"La Jolla Pharmaceutical","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"U.S.A","productType":"Peptide, Unconjugated","year":"2021","type":"Inapplicable","leadProduct":"Angiotensin II","moa":"Type-1 angiotensin II receptor","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase IV","graph3":"Northwestern University","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Northwestern University \/ La Jolla Pharmaceutical","highestDevelopmentStatusID":"11","companyTruncated":"Northwestern University \/ La Jolla Pharmaceutical"},{"orgOrder":0,"company":"University of New Mexico","sponsor":"La Jolla Pharmaceutical | National Center for Advancing Translational Sciences","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"U.S.A","productType":"Peptide, Unconjugated","year":"2022","type":"Inapplicable","leadProduct":"Angiotensin II","moa":"Type-1 angiotensin II receptor","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase IV","graph3":"University of New Mexico","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"University of New Mexico \/ La Jolla Pharmaceutical | National Center for Advancing Translational Sciences","highestDevelopmentStatusID":"11","companyTruncated":"University of New Mexico \/ La Jolla Pharmaceutical | National Center for Advancing Translational Sciences"},{"orgOrder":0,"company":"University of New Mexico","sponsor":"La Jolla Pharmaceutical","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"U.S.A","productType":"Peptide, Unconjugated","year":"2023","type":"Inapplicable","leadProduct":"Angiotensin II","moa":"Type-1 angiotensin II receptor","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase IV","graph3":"University of New Mexico","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"University of New Mexico \/ La Jolla Pharmaceutical","highestDevelopmentStatusID":"11","companyTruncated":"University of New Mexico \/ La Jolla Pharmaceutical"},{"orgOrder":0,"company":"Gregory Gilot","sponsor":"LifeNet Health | Cleveland Clinic","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"","productType":"Undisclosed","year":"2018","type":"Inapplicable","leadProduct":"Human Acellular Dermal Matrix","moa":"Undisclosed","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase IV","graph3":"Gregory Gilot","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Gregory Gilot \/ LifeNet Health | Cleveland Clinic","highestDevelopmentStatusID":"11","companyTruncated":"Gregory Gilot \/ LifeNet Health | Cleveland Clinic"},{"orgOrder":0,"company":"Anders Perner, MD, PhD","sponsor":"Rigshospitalet | Centre for Research in Intensive Care | Scandinavian Critical Care Trials Group","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"","productType":"Undisclosed","year":"2018","type":"Inapplicable","leadProduct":"Isotonic Crystalloid","moa":"Undisclosed","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase IV","graph3":"Anders Perner, MD, PhD","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Anders Perner, MD, PhD \/ Rigshospitalet | Centre for Research in Intensive Care | Scandinavian Critical Care Trials Group","highestDevelopmentStatusID":"11","companyTruncated":"Anders Perner, MD, PhD \/ Rigshospitalet | Centre for Research in Intensive Care | Scandinavian Critical Care Trials Group"},{"orgOrder":0,"company":"CellTherX","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"","productType":"Cell & Gene Therapy","year":"2020","type":"Inapplicable","leadProduct":"Microsurfaced Skin Graft","moa":"Undisclosed","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase IV","graph3":"CellTherX","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"CellTherX \/ Undisclosed","highestDevelopmentStatusID":"11","companyTruncated":"CellTherX \/ Undisclosed"},{"orgOrder":0,"company":"Moleac","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"SINGAPORE","productType":"Undisclosed","year":"2015","type":"Inapplicable","leadProduct":"Neuroaid","moa":"Undisclosed","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase IV","graph3":"Moleac","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Moleac \/ Undisclosed","highestDevelopmentStatusID":"11","companyTruncated":"Moleac \/ Undisclosed"},{"orgOrder":0,"company":"Augusta University","sponsor":"NuTech Medical","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"U.S.A","productType":"Oligonucleotide","year":"2014","type":"Inapplicable","leadProduct":"Nucel","moa":"Undisclosed","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase IV","graph3":"Augusta University","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Augusta University \/ NuTech Medical","highestDevelopmentStatusID":"11","companyTruncated":"Augusta University \/ NuTech Medical"},{"orgOrder":0,"company":"The Hospital for Sick Children","sponsor":"Physician Services Incorporated | Merck & Co","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"CANADA","productType":"Vaccine","year":"2015","type":"Inapplicable","leadProduct":"Quadrivalent Human Papillomavirus Vaccine","moa":"Undisclosed","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase IV","graph3":"The Hospital for Sick Children","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Pill","sponsorNew":"The Hospital for Sick Children \/ Physician Services Incorporated | Merck & Co","highestDevelopmentStatusID":"11","companyTruncated":"The Hospital for Sick Children \/ Physician Services Incorporated | Merck & Co"},{"orgOrder":0,"company":"GeneScience Pharmaceuticals Co Ltd","sponsor":"Shanghai Jiaotong University School of Medicine | Beijing Children's Hospital | Third Military Medical University","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"CHINA","productType":"Protein","year":"2013","type":"Inapplicable","leadProduct":"Recombinant Human GM-CSF","moa":"Undisclosed","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase IV","graph3":"GeneScience Pharmaceuticals Co Ltd","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Gel","sponsorNew":"GeneScience Pharmaceuticals Co Ltd \/ Shanghai Jiaotong University School of Medicine | Beijing Children's Hospital | Third Military Medical University","highestDevelopmentStatusID":"11","companyTruncated":"GeneScience Pharmaceuticals Co Ltd \/ Shanghai Jiaotong University School of Medicine | Beijing Children's Hospital | Third Military Medical University"},{"orgOrder":0,"company":"Rigshospitalet","sponsor":"Octapharma","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"DENMARK","productType":"Undisclosed","year":"2016","type":"Inapplicable","leadProduct":"Ringer-acetat","moa":"Undisclosed","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase IV","graph3":"Rigshospitalet","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Rigshospitalet \/ Octapharma","highestDevelopmentStatusID":"11","companyTruncated":"Rigshospitalet \/ Octapharma"},{"orgOrder":0,"company":"St. Louis University","sponsor":"Next Science","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"U.S.A","productType":"Undisclosed","year":"2023","type":"Inapplicable","leadProduct":"Surgx Wound Gel","moa":"Undisclosed","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase IV","graph3":"St. Louis University","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Gel","sponsorNew":"St. Louis University \/ Next Science","highestDevelopmentStatusID":"11","companyTruncated":"St. Louis University \/ Next Science"},{"orgOrder":0,"company":"Fresenius Kabi AB Brunna","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"SWEDEN","productType":"Miscellaneous","year":"2012","type":"Inapplicable","leadProduct":"Volulyte","moa":"Undisclosed","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase IV","graph3":"Fresenius Kabi AB Brunna","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Solution","sponsorNew":"Fresenius Kabi AB Brunna \/ Undisclosed","highestDevelopmentStatusID":"11","companyTruncated":"Fresenius Kabi AB Brunna \/ Undisclosed"},{"orgOrder":0,"company":"Intermountain Health","sponsor":"University of Utah","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"U.S.A","productType":"Hormone","year":"2024","type":"Inapplicable","leadProduct":"Arginine Vasopressin","moa":"Vasopressin receptor","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase IV","graph3":"Intermountain Health","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Infusion","sponsorNew":"Intermountain Health \/ University of Utah","highestDevelopmentStatusID":"11","companyTruncated":"Intermountain Health \/ University of Utah"},{"orgOrder":0,"company":"BTG INTERNATIONAL INC","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2013","type":"Inapplicable","leadProduct":"Crotalidae Immune Fab","moa":"Venom toxin","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase IV","graph3":"BTG INTERNATIONAL INC","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"BTG INTERNATIONAL INC \/ Undisclosed","highestDevelopmentStatusID":"11","companyTruncated":"BTG INTERNATIONAL INC \/ Undisclosed"},{"orgOrder":0,"company":"Catholic University of Korea","sponsor":"Viatris","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"SOUTH KOREA","productType":"Miscellaneous","year":"2024","type":"Inapplicable","leadProduct":"Pregabalin","moa":"Voltage-gated calcium channel","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase IV","graph3":"Catholic University of Korea","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Catholic University of Korea \/ Viatris","highestDevelopmentStatusID":"11","companyTruncated":"Catholic University of Korea \/ Viatris"},{"orgOrder":0,"company":"Pacira BioSciences","sponsor":"Steven Orebaugh","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"U.S.A","productType":"Miscellaneous","year":"2017","type":"Inapplicable","leadProduct":"Bupivacaine","moa":"Sodium channel protein type IV alpha subunit","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase IV","graph3":"Pacira BioSciences","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Injection","sponsorNew":"Pacira BioSciences \/ Steven Orebaugh","highestDevelopmentStatusID":"11","companyTruncated":"Pacira BioSciences \/ Steven Orebaugh"},{"orgOrder":0,"company":"Synedgen","sponsor":"J. Peter Rubin, MD","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"U.S.A","productType":"Undisclosed","year":"2020","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase IV","graph3":"Synedgen","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Hydrogel","sponsorNew":"Synedgen \/ J. Peter Rubin, MD","highestDevelopmentStatusID":"11","companyTruncated":"Synedgen \/ J. Peter Rubin, MD"}]

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : Cerebrolysin

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Study Phase : Phase IV

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Cerebrolysin is a drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Brain Injuries, Traumatic.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          May 25, 2012

                          Lead Product(s) : Cerebrolysin

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase IV

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Ever Pharma CB

                          02

                          First Affiliated Hospital of Wannan Medical College

                          Country arrow
                          Florida Innovation
                          Not Confirmed

                          First Affiliated Hospital of Wannan Medical College

                          Country arrow
                          Florida Innovation
                          Not Confirmed

                          Details : Shenfu is a Plant Extract/Herbal drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Shock, Septic.

                          Product Name : Undisclosed

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : Inapplicable

                          April 08, 2025

                          Lead Product(s) : Shenfu

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase IV

                          Sponsor : Wuhu City Second People’s Hospital

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Florida Innovation
                          Not Confirmed
                          Florida Innovation
                          Not Confirmed

                          Details : Mirikizumab is a Antibody drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Pouchitis.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          March 07, 2025

                          Lead Product(s) : Mirikizumab

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase IV

                          Sponsor : Eli Lilly

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          Florida Innovation
                          Not Confirmed
                          Florida Innovation
                          Not Confirmed

                          Details : NexoBrid (anacaulase-bcdb) is a topically administered biological product that enzymatically removes nonviable burn tissue, approved the treatment of severe burns.

                          Product Name : NexoBrid

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          August 05, 2024

                          Lead Product(s) : Bromelain,Anacaulase

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase IV

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Catholic University of Korea

                          Country arrow
                          Florida Innovation
                          Not Confirmed

                          Catholic University of Korea

                          Country arrow
                          Florida Innovation
                          Not Confirmed

                          Details : Pregabalin is a Other Small Molecule drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Rotator Cuff Injuries.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          April 16, 2024

                          Lead Product(s) : Pregabalin

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase IV

                          Sponsor : Viatris

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Florida Innovation
                          Not Confirmed
                          Florida Innovation
                          Not Confirmed

                          Details : Rifaximin is a Antibiotic drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Pouchitis.

                          Product Name : Undisclosed

                          Product Type : Antibiotic

                          Upfront Cash : Inapplicable

                          March 15, 2024

                          Lead Product(s) : Rifaximin

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase IV

                          Sponsor : Bausch Health

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          North Memorial Health Care

                          Country arrow
                          Florida Innovation
                          Not Confirmed

                          North Memorial Health Care

                          Country arrow
                          Florida Innovation
                          Not Confirmed

                          Details : Ketamine is a Controlled Substance drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Thoracic Injury.

                          Product Name : Undisclosed

                          Product Type : Controlled Substance

                          Upfront Cash : Inapplicable

                          February 01, 2024

                          Lead Product(s) : Ketamine Hydrochloride

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase IV

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Intermountain Health

                          Country arrow
                          Florida Innovation
                          Not Confirmed

                          Intermountain Health

                          Country arrow
                          Florida Innovation
                          Not Confirmed

                          Details : Vasopressin is a Protein drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Shock, Septic.

                          Product Name : Undisclosed

                          Product Type : Hormone

                          Upfront Cash : Inapplicable

                          January 22, 2024

                          Lead Product(s) : Arginine Vasopressin

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase IV

                          Sponsor : University of Utah

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Kingman Regional Medical Center

                          Country arrow
                          Florida Innovation
                          Not Confirmed

                          Kingman Regional Medical Center

                          Country arrow
                          Florida Innovation
                          Not Confirmed

                          Details : Angiotensin II is a Peptide drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Shock, Septic.

                          Product Name : Undisclosed

                          Product Type : Peptide, Unconjugated

                          Upfront Cash : Inapplicable

                          November 08, 2023

                          Lead Product(s) : Angiotensin II

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase IV

                          Sponsor : La Jolla Pharmaceutical

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          Florida Innovation
                          Not Confirmed
                          Florida Innovation
                          Not Confirmed

                          Details : Centhaquine is a Other Small Molecule drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Shock.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          July 21, 2023

                          Lead Product(s) : Centhaquine

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase IV

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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