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II","graph3":"BILIX","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Injection","sponsorNew":"BILIX \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"BILIX \/ Undisclosed"},{"orgOrder":0,"company":"Graegis Pharmaceuticals Ltd","sponsor":"Excelya","pharmaFlowCategory":"DU","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"UNITED KINGDOM","productType":"Antibody-drug Conjugate","year":"2025","type":"Inapplicable","leadProduct":"GR1014","moa":"Undisclosed","graph1":"Trauma (Emergency, Injury, Surgery)","graph2":"Phase II","graph3":"Graegis Pharmaceuticals Ltd","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Trauma","amount2New":0,"dosageForm":"Gel","sponsorNew":"Graegis Pharmaceuticals Ltd \/ Excelya","highestDevelopmentStatusID":"8","companyTruncated":"Graegis Pharmaceuticals Ltd \/ Excelya"}]

Find Drugs for Trauma (Emergency, Injury, Surgery) in Phase II Clinical Development

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                          Top Deals by Deal Size (USD bn)

                          01

                          Details : Elezanumab is a monoclonal antibody of the human immunoglobulin (Ig)G1 isotype that binds selectively to repulsive guidance molecule A (RGMa). Elezanumab is being investigated to treat spinal cord injuries, multiple sclerosis and acute ischemic stroke.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          September 28, 2020

                          Lead Product(s) : Elezanumab

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Abbvie Company Banner

                          02

                          Details : Elezanumab is a Antibody drug candidate, which is currently being evaluated in phase II clinical studies for the treatment of Spinal Cord Injuries.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          March 04, 2020

                          Lead Product(s) : Elezanumab

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Abbvie Company Banner

                          03

                          Graegis Pharmaceuticals Ltd

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Graegis Pharmaceuticals Ltd

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Details : GR1014 is a Antibody-drug Conjugate drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Radiodermatitis.

                          Product Name : Undisclosed

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Inapplicable

                          September 25, 2025

                          Lead Product(s) : GR1014

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase II

                          Sponsor : Excelya

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : The proceeds will be used to advance the clinical development of its lead botanical candidate KV23A, which is being positioned to enter a registerable Phase 3 program.

                          Product Name : KV23a

                          Product Type : Plant Extract/Herbal

                          Upfront Cash : Undisclosed

                          September 19, 2025

                          Lead Product(s) : KV23a

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase II

                          Sponsor : GEM Global Yield

                          Deal Size : $120.0 million

                          Deal Type : Financing

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                          05

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : (BX-001N) is currently being evaluated in Phase II clinical studies for the treatment of Reperfusion Injury.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          September 10, 2025

                          Lead Product(s) : BX-001N

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Pontificia Universidad Catolica de Chile

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Pontificia Universidad Catolica de Chile

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Details : This drug candidate is currently being evaluated in Phase II clinical studies for the treatment of Wounds and Injuries.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          September 05, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase II

                          Sponsor : Hospital del Trabajador de Santiago | SymbiOx Inc.

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : The fund will be used for company's ongoing ONP-002, a First-in-Class Enantiomeric-Neurosteroid being developed for the treatment of mild Traumatic Brain Injury.

                          Product Name : Undisclosed

                          Product Type : Steroid

                          Upfront Cash : Undisclosed

                          July 02, 2025

                          Lead Product(s) : ONP-002

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase II

                          Sponsor : Dawson James Securities

                          Deal Size : $16.5 million

                          Deal Type : Public Offering

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                          08

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : The fund will be used for company's ongoing ONP-002, a First-in-Class Enantiomeric-Neurosteroid being developed for the treatment of mild Traumatic Brain Injury.

                          Product Name : Undisclosed

                          Product Type : Steroid

                          Upfront Cash : Undisclosed

                          July 01, 2025

                          Lead Product(s) : ONP-002

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase II

                          Sponsor : Dawson James Securities

                          Deal Size : $20.0 million

                          Deal Type : Public Offering

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                          09

                          OTS 2025
                          Not Confirmed
                          OTS 2025
                          Not Confirmed

                          Details : KJ101 is a Antibody drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Burns.

                          Product Name : Undisclosed

                          Product Type : Antibody, Unconjugated

                          Upfront Cash : Inapplicable

                          June 17, 2025

                          Lead Product(s) : KJ101

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          Third Affiliated Hospital, Sun Yat-sen University

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Third Affiliated Hospital, Sun Yat-sen University

                          Country arrow
                          OTS 2025
                          Not Confirmed

                          Details : XS228 is a Cell and Gene therapy drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Spinal Cord Injuries.

                          Product Name : Undisclosed

                          Product Type : Cell & Gene Therapy

                          Upfront Cash : Inapplicable

                          May 16, 2025

                          Lead Product(s) : XS228

                          Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                          Highest Development Status : Phase II

                          Sponsor : Xellsmart

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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