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Nephritis","therapeuticArea":"Immunology","highestDevelopmentStatus":"IND Enabling","country":"U.S.A","productType":"Cell and Gene therapy","productStatus":"New Molecular Entity","date":"August 2023","url1":"","url2":"","graph1":"Cell and Gene therapy","graph2":"Artiva Biotherapeutics"},{"orgOrder":0,"company":"Tourmaline Bio","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Tourmaline Bio Announces FDA Clearance of Investigational New Drug (IND) Application for TOUR006, an Anti-IL-6 Antibody With a Differentiated Profile for the Treatment of Thyroid Eye Disease (TED)","therapeuticArea":"Immunology","highestDevelopmentStatus":"IND Enabling","country":"U.S.A","productType":"Large molecule","productStatus":"New Molecular Entity","date":"August 2023","url1":"","url2":"","graph1":"Large molecule","graph2":"Tourmaline Bio"},{"orgOrder":0,"company":"ReAlta Life Sciences","sponsor":"Not 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Find Clinical Drug Development Pipelines & Deals | PipelineProspector
CLN-978 is a novel, highly potent, half-life extended CD19xCD3 bispecific T cell engager construct. It is being evaluated for autoimmune diseases, with systemic lupus erythematosus as a first indication.
CT103A (equecabtagene autoleucel) is a BCMA chimeric antigen receptor autologous T cell therapy, being investigated for the treatment of Generalized Myasthenia Gravis.
SYNCAR-001, an autologous CD19-targeted CAR-T in combination with STK-009 is a human orthogonal IL-2 cytokine is being evaluated for the treatment of lupus without lymphodepletion.
Under the agreement, GenBio will license potentially new, next generation of anti-inflammatory cannabinoids to be included in Strainsforpains CBD branded products.
Under the agreement, Allogene will use Arbor’s proprietary CRISPR gene-editing technology in its next generation AlloCAR T platform, ALLO-329, for the treatment of autoimmune disease (AID).
LP-410 is designed to target the underlying mechanisms of Oral Graft-Versus-Host Disease (GVHD), potentially providing a safe and effective treatment option for affected individuals.
ATA3219 is an allogeneic CAR T-cell therapy targeting CD19+ B Cells, consists of allogeneic EBV T cells. It is being evaluated for the treatment of systemic lupus erythematosus with kidney involvement.
Through financing, Vandria will be focusing on the mitophagy drug candidate VNA-052 to generate pre-clinical data in Vandria’s muscle program for the treatment of sporadic inclusion body myositis.
The net proceeds will be used to bring universal allogeneic regulatory T (Treg), including TRX103 and CAR-Treg cell therapies, TRX301, to the clinic to treat and potentially cure autoimmune and inflammatory diseases.
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