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                          01

                          Lead Product(s) : Paliperidone

                          Therapeutic Area : Psychiatry/Psychology

                          Study Phase : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Undisclosed

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          February 07, 2018

                          Lead Product(s) : Paliperidone

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Pharmathen

                          02

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                          ESCRS
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                          Details : The combined entity, to be called Phytanix, Inc, will bring together two pipelines focused on stress-related and CNS disorders such as PT-00114, is being evaluated for Treatment-Resistant Depression.

                          Product Name : Undisclosed

                          Product Type : Peptide

                          Upfront Cash : Undisclosed

                          May 21, 2025

                          Lead Product(s) : PT-00114

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Phytanix Bio

                          Deal Size : Undisclosed

                          Deal Type : Merger

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                          03

                          ESCRS
                          Not Confirmed
                          ESCRS
                          Not Confirmed

                          Details : The combined entity, to be called Phytanix, Inc, will bring together two pipelines focused on stress-related and CNS disorders such as PT-00114, is being evaluated for Treatment-Resistant Depression.

                          Product Name : Undisclosed

                          Product Type : Peptide

                          Upfront Cash : Undisclosed

                          May 19, 2025

                          Lead Product(s) : PT-00114

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Phytanix Bio

                          Deal Size : Undisclosed

                          Deal Type : Merger

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                          04

                          ESCRS
                          Not Confirmed
                          ESCRS
                          Not Confirmed

                          Details : CMND-100 (5-methoxy-2-aminoindane) is a 5-HT1A receptor modulator, small molecule drug candidate, which is being evaluated for the treatment of alcohol use disorder.

                          Product Name : Undisclosed

                          Product Type : Controlled Substance

                          Upfront Cash : Inapplicable

                          April 23, 2025

                          Lead Product(s) : 5-Methoxy-2-Aminoindane

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          ESCRS
                          Not Confirmed
                          ESCRS
                          Not Confirmed

                          Details : CMND-100 (5-methoxy-2-aminoindane) is a 5-HT1A receptor modulator, small molecule drug candidate, which is being evaluated for the treatment of alcohol use disorder.

                          Product Name : Undisclosed

                          Product Type : Controlled Substance

                          Upfront Cash : Inapplicable

                          April 16, 2025

                          Lead Product(s) : 5-Methoxy-2-Aminoindane

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          ESCRS
                          Not Confirmed
                          ESCRS
                          Not Confirmed

                          Details : CMND-100 (5-methoxy-2-aminoindane) is a 5-HT1A receptor modulator, small molecule drug candidate, which is being evaluated for the treatment of alcohol use disorder.

                          Product Name : Undisclosed

                          Product Type : Controlled Substance

                          Upfront Cash : Inapplicable

                          April 10, 2025

                          Lead Product(s) : 5-Methoxy-2-Aminoindane

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          ESCRS
                          Not Confirmed
                          ESCRS
                          Not Confirmed

                          Details : TSND-201, a rapid-acting neuroplastogen, is a proprietary formulation of methylone. It is being evaluated for PTSD.

                          Product Name : Undisclosed

                          Product Type : Controlled Substance

                          Upfront Cash : Inapplicable

                          March 31, 2025

                          Lead Product(s) : Methylone

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          ESCRS
                          Not Confirmed
                          ESCRS
                          Not Confirmed

                          Details : CMND-100 (5-methoxy-2-aminoindane) is a 5-HT inhibitor, a MEAI-based psychedelic-derived drug candidate which is being investigated for the treatment of alcohol use disorder.

                          Product Name : Undisclosed

                          Product Type : Controlled Substance

                          Upfront Cash : Inapplicable

                          March 18, 2025

                          Lead Product(s) : 5-Methoxy-2-Aminoindane

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          ESCRS
                          Not Confirmed
                          ESCRS
                          Not Confirmed

                          Details : PharmAla develop a new 20mg clinical drug product dose of its LaNeo™ MDMA to examine tolerability of MDMA in Schizophrenia.

                          Product Name : Undisclosed

                          Product Type : Controlled Substance

                          Upfront Cash : Undisclosed

                          February 27, 2025

                          Lead Product(s) : Midomafetamine

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : UT Health San Antonio

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          10

                          ESCRS
                          Not Confirmed
                          ESCRS
                          Not Confirmed

                          Details : CMND-100 (5-methoxy-2-aminoindane) is a 5-HT inhibitor, a MEAI-based psychedelic-derived drug candidate which is being investigated for the treatment of alcohol use disorder.

                          Product Name : Undisclosed

                          Product Type : Controlled Substance

                          Upfront Cash : Inapplicable

                          December 24, 2024

                          Lead Product(s) : 5-Methoxy-2-Aminoindane

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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