Company profile for Pharmathen SA

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Pharmathen provides life cycle Management solutions for branded pharma, as well as to develop & establish new technology platforms.

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About

Pharmathen, established in 1969, has emerged as a leading in-house development partner in Europe. It specializes in the development, registration, manufacturing & life-cycle management of complex pharmaceutical technologies & generic formulations. With a portfolio of over 100 products, Pharmathen serves over 250 clients across 80 countries. It’s pipeline includes advanced long-acting injectables, sustained-release formulations & preservative-free ophthalmics manufactured in USFDA & EU-approved facilities. Pharmathen’s core technology platforms, including microspheres, nanosuspensions & nanogels, are used to develop long-acting therapies.

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Country
Greece
Address
Address
44, Kifissias Avenue, 15125 Marousi Attica
Telephone
Telephone
+30 2106604300
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CORPORATE CONTENT #SupplierSpotlight

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DATA COMPILATION #PharmaFlow

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Chinese FDA-registered generic facilities gain steam, India maintains lead with 396 facilities
Every year, the US Food and Drug Administration (FDA) publishes the user fee amounts it will collect from manufacturers of pharmaceuticals, generic drugs, biosimilars and medical devices in the coming financial year. The fee for fiscal year 2025 under the Generic Drug User Fee Act (GDUFA) was published on July 31, 2024.The GDUFA, established in 2012, authorizes FDA to assess and collect fees from drug manufacturers to expedite the delivery of safe, high-quality, and affordable generic drugs to the American public.The FDA’s facility payments list under GDUFA reveals that as of November 14, 2024, 1,397 facilities had paid their registration fees for financial year 2025. Of these facilities, 707 or 50.6 percent are active pharmaceutical ingredients (API) facilities, 405 or 29 percent are finished dosage forms (FDF) facilities, 69 (4.9 percent) are facilities that produce both APIs and FDFs, and 216 (15.5 percent) are contract manufacturing services (CMO) sites.Teva Pharmaceuticals, with 29 facility registrations, led the list of companies, followed by Aurobindo Pharma, Sun Pharma, and Dr. Reddy's Laboratories. Fiscal year Facility Registrations 2016 1,425 2017 1,442 2018 1,269 2019 1,286 2020 1,300 2021 1,340 2022 1,385 2023 1,394 2024 1,447 2025 1,397  Generic Drug Facilities Registered with the US FDA for FY2025 (Free Excel Available)India continues to lead with 396 facilities, US and China follow India maintains its dominance in total facility registrations with the FDA, registering 396 facilities for FY2025. This includes 214 API facilities, 135 FDF facilities, 21 facilities engaged in both API and FDF activities, and 26 CMO facilities.The United States holds the second position with 328 facilities, while China strengthened its third position with 197 facilities.With 214 API facilities, India continues to have the largest share of API manufacturing sites, outmatching the combined total of China (128) and the US (83), which together account for 211 facilities. Among European manufacturers, Italy leads with 59 API manufacturing sites, followed by Spain (30) and Germany (25).The US has maintained its lead in FDF facilities with 143 sites, followed closely by India with 135 sites and China with 45 sites. Country API FDF Both CMO Total India 214 135 21 26 396 US 83 143 13 89 328 China 128 45 12 12 197 Italy 59 3 2 19 83 Germany 25 4 1 15 45 Spain 30 9 1 4 44 Canada 7 17   13 37 Taiwan 9 6 5 4 24 Switzerland 15 4   4 23 France 16     6 22 Japan 18   1   19 United Kingdom 12 1   2 15 Mexico 9 1   1 11 Ireland 5 5   1 11   Generic Drug Facilities Registered with the US FDA for FY2025 (Free Excel Available) GDUFA III user fee rates increase across categories for FY25The GDUFA, which was reauthorized on September 30, 2022 (as GDUFA III), continues with provisions that will last until September 30, 2027. In July 2024, the FDA published updated user fee rates for FY2025.The facility fees have seen increases across all categories. API facility fees increased by 3 percent for domestic sites (to US$ 41,580) and 2 percent for foreign sites (to US$ 56,580). FDF facility fees rose by 5 percent for both domestic (to US$ 231,952) and foreign sites (to US$ 246,952). CMO facility fees increased by 5 percent for domestic sites (to US$ 55,668) and 4 percent for foreign sites (to US$ 70,668).Additionally, the fee for large-, medium- and small-sized drug applicants has increased by over 9 percent, compared to the 7 percent increase seen in 2023. Generic Drug Facilities Registered with the US FDA for FY2025 (Free Excel Available) China leads new facility registrations as FDA records 41 new units in FY25Out of the total 1,397 facilities registered for FY2025, 41 were new registrations (going by Facility FDA Establishment Identifier numbers). China led the way with 13 new facilities, followed closely by India with 11 new facilities, while the US secured the third position with eight new facilities.The new registrations included 15 API facilities, 13 CMO facilities, 12 FDF facilities, and one facility engaged in both API and FDF activities. Chinese companies dominated the new FDF registrations with six facilities: Chengdu Shuode Pharma, Chengdu Suncadia Medicine, Cipla (Jiangsu), GE Healthcare (Shanghai), Luoxin Aurovitas Pharma (Chengdu), and Zhejiang Xianju Pharma.India added two new FDF facilities through Eugia Steriles and Zydus Pharma. Malaysia registered two FDF facilities through Novugen Pharma and Novugen Oncology, while Turkey’s Insud Pharma subsidiary Exeltis and US’ RK Pharma registered one FDF facility each.The 13 new CMO facilities included, Acme Generics, Emcure, Esjay Pharma, Fordoz Pharma, Fourrts Laboratories, Laboratoires KABS, PharmaMax, Quality Packaging Specialists International, Ritsa Pharma, Shanghai Aucyun Pharma, Sichuan Huiyu Pharma, Taejoon Pharm, and Tubilux Pharma.In the API category, the 15 new registrations included Acharya Chemicals, Hainan Poly Pharma, CBL Patras, EUROAPI, Hybio Pharma, Medilux Laboratories, Metrochem API, Purolite, Chengdu Easton Biopharma, Sionc Pharma, Smithfield Bioscience, Xttrium Laboratories, Zhejiang Hengkang Pharma, Moehs Iberica and Shilpa Pharma. Armstrong Pharmaceuticals registered the sole facility for both APIs and FDFs.So far, 92 facilities have not renewed their registration. Among these was a facility owned by Sandoz subsidiary Eon Labs in Wilson, North Carolina (US), which is permanently closed. In fact, the geographical distribution of non-renewals shows that 30 facilities were from the US, while India and China accounted for 14 and nine non-renewals respectively. Generic Drug Facilities Registered with the US FDA for FY2025 (Free Excel Available) Our viewThe FY 2025 GDUFA facility registration data indicates a continued strong presence of Indian manufacturers in the US generic drug market, particularly in API production. However, China's leadership in new facility registrations, especially in FDF manufacturing, suggests that the global generic drug supply chain landscape may evolve considerably in the coming years. 

Impressions: 15546

https://www.pharmacompass.com/radio-compass-blog/chinese-fda-registered-generic-facilities-gain-steam-india-maintains-lead-with-396-facilities

#PharmaFlow by PHARMACOMPASS
21 Nov 2024

NEWS #PharmaBuzz

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https://www.prnewswire.com/news-releases/ntc-backed-by-wise-equity-completes-the-acquisition-of-pharmathens-ophthalmology-business-302634307.html

PR NEWSWIRE
10 Dec 2025

https://www.pharmathen.com/Pharmathen-Achieves-EcoVadis-Silver-Medal-for-Sustainability-in-2025

PRESS RELEASE
11 Oct 2025

https://www.pharmathen.com/Pharmathen-announces-John-Nason-as-incoming-Group-CEO-succeeding-Dimitris-Kadis

PRESS RELEASE
17 Jul 2025

https://www.pharmathen.com/Pharmathen-supports-Ronald-McDonald-House-Charities-Hellas-for-the-second-consecutive-year

PRESS RELEASE
11 Jul 2025

https://www.pharmathen.com/Advanz-pharma-and-Pharmathen-expand-strategic-partnership

PRESS RELEASE
15 May 2025

https://www.pharmathen.com/Neuraxpharm-and-Pharmathen-enter-into-strategic-co-development-agreement

PRESS RELEASE
13 Dec 2024

Drugs in Development

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Details:

The agreement aims to co-develop new long-acting injectable therapies within the psychiatry field under Pharmathen’s long-acting therapeutic technologies (LATT) program.


Lead Product(s): Undisclosed

Therapeutic Area: Psychiatry/Psychology Brand Name: Undisclosed

Study Phase: UndisclosedProduct Type: Undisclosed

Sponsor: Neuraxpharm

Deal Size: Undisclosed Upfront Cash: Undisclosed

Deal Type: Agreement December 12, 2024

Pharmathen

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Pharmathen SA

Greece
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Lead Product(s) : Undisclosed

Therapeutic Area : Psychiatry/Psychology

Highest Development Status : Undisclosed

Partner/Sponsor/Collaborator : Neuraxpharm

Deal Size : Undisclosed

Deal Type : Agreement

Details : The agreement aims to co-develop new long-acting injectable therapies within the psychiatry field under Pharmathen’s long-acting therapeutic technologies (LATT) program.

Product Name : Undisclosed

Product Type : Undisclosed

Upfront Cash : Undisclosed

December 12, 2024

Pharmathen

Details:

Partners Group to Acquire Pharmathen, a Leading European Pharmaceutical Company, from BC Partners


Lead Product(s): Undisclosed

Therapeutic Area: Ophthalmology Brand Name: Undisclosed

Study Phase: UndisclosedProduct Type: Undisclosed

Sponsor: Partners Group

Deal Size: $1,900.0 million Upfront Cash: Undisclosed

Deal Type: Acquisition July 19, 2021

Pharmathen

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Pharmathen SA

Greece
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Lead Product(s) : Undisclosed

Therapeutic Area : Ophthalmology

Highest Development Status : Undisclosed

Partner/Sponsor/Collaborator : Partners Group

Deal Size : $1,900.0 million

Deal Type : Acquisition

Details : Partners Group to Acquire Pharmathen, a Leading European Pharmaceutical Company, from BC Partners

Product Name : Undisclosed

Product Type : Undisclosed

Upfront Cash : Undisclosed

July 19, 2021

Pharmathen

Details:

Paliperidone is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Schizophrenia.


Lead Product(s): Paliperidone

Therapeutic Area: Psychiatry/Psychology Brand Name: Undisclosed

Study Phase: Phase I/ Phase IIProduct Type: Miscellaneous

Sponsor: Undisclosed

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable February 07, 2018

Pharmathen

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Pharmathen SA

Greece
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Lead Product(s) : Paliperidone

Therapeutic Area : Psychiatry/Psychology

Highest Development Status : Phase I/ Phase II

Partner/Sponsor/Collaborator : Undisclosed

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : Paliperidone is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Schizophrenia.

Product Name : Undisclosed

Product Type : Miscellaneous

Upfront Cash : Inapplicable

February 07, 2018

Pharmathen

Details:

MDX1303 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Anthrax.


Lead Product(s): MDX1303

Therapeutic Area: Infections and Infectious Diseases Brand Name: Undisclosed

Study Phase: Phase IProduct Type: Undisclosed

Sponsor: Department of Health and Human Services | National Institute of Allergy and Infectious Diseases | National Institutes of Health

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable December 23, 2010

Pharmathen

04

Pharmathen SA

Greece
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Lead Product(s) : MDX1303

Therapeutic Area : Infections and Infectious Diseases

Highest Development Status : Phase I

Partner/Sponsor/Collaborator : Department of Health and Human Services | National Institute of Allergy and Infectious Diseases | National Institutes of Health

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : MDX1303 is a drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Anthrax.

Product Name : Undisclosed

Product Type : Undisclosed

Upfront Cash : Inapplicable

December 23, 2010

Pharmathen

Details:

Valortim is a Antibody drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Hypersensitivity.


Lead Product(s): Valortim

Therapeutic Area: Immunology Brand Name: Undisclosed

Study Phase: Phase IProduct Type: Antibody, Unconjugated

Sponsor: National Institute of Allergy and Infectious Diseases | National Institutes of Health

Deal Size: Inapplicable Upfront Cash: Inapplicable

Deal Type: Inapplicable September 17, 2010

Pharmathen

05

Pharmathen SA

Greece
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Lead Product(s) : Valortim

Therapeutic Area : Immunology

Highest Development Status : Phase I

Partner/Sponsor/Collaborator : National Institute of Allergy and Infectious Diseases | National Institutes of Health

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : Valortim is a Antibody drug candidate, which is currently being evaluated in phase I clinical studies for the treatment of Hypersensitivity.

Product Name : Undisclosed

Product Type : Antibody, Unconjugated

Upfront Cash : Inapplicable

September 17, 2010

Pharmathen
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Pharmathen SA is a supplier offers 22 products (APIs, Excipients or Intermediates).

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