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Anhydrous Lactose
Carbomer Homopolymer Type A
Crospovidone
Dibasic Calcium Phosphate
Fructose
Hydrogenated Castor Oil
Hydroxypropyl Methylcellulose
Lactose Monohydrate
Lauryl Sulfate
Maltose Sugar
Mannitol
Microcrystalline Cellulose
Microprilled Poloxamer
Native & Pregelatinized Corn Starch
Polacrilin Potassium
Polyethylene Oxide
Polyoxyl 40 Hydrogenated Castor Oil
Polyoxyl 40 hydrogenated castor oil
Polysorbate 80
Polyvinylpyrrolidone Crosslinked
Povidone
Sodium Lauryl Sulfate
Stearic Acid
Stearyl Alcohol
Vinylpyrrolidone-Vinyl Acetate
Vinylpyrrolidone-Vinyl Acetate Copolymer
BASF
Corel Pharma Chem
DFE Pharma
Gangwal Chemicals
Lubrizol Life Science Health
Microlex e.U
SPI Pharma
Seppic
Sigachi Industries
The Dow Chemical Company
AUSTRIA
FRANCE
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UNITED STATES
Global leader in Excipient Solutions
Applications: Pharmacel® 102 has good flow properties enabling high speed direct compression tableting. It is a ideal choice for direct compression & dry granulation formulations and it also has some lubrication properties for smooth tableting experience.
Ingredient(s): Microcrystalline Cellulose
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Density- Tapped density- 440 g/l, Bulk density- 310 g/l; Particle size- D10- 40 ?m, D50- 90 ?m, D90-180 ?m; Hausner ratio-1,42
Solving Formulation Challenges Using Superior Functional Materials
Applications: Advantol® 300 Polyol Drug Delivery system is a directly compressible paltform to create soft chew or soft melt oral dosage forms.It is a robust system that allows fast product development.
Ingredient(s): Mannitol
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
Applications: Diluent, Cushioning Agent
Ingredient(s): Dibasic Calcium Phosphate
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
Global leader in Excipient Solutions
Applications: SuperTab® 11SD offers the best compactability of all grades of lactose, and it is well suited to direct compression applications. Due to the low moisture content, it is used in the formulations containing moisture sensitive drugs.
Ingredient(s): Anhydrous Lactose
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Density- Tapped density- 906 g/l, Bulk density- 722 g/l; Particle size- D10-15 ?m, D50- 170 ?m, D90- 340 ?m; Hausner ratio-1,25
Solving Formulation Challenges Using Superior Functional Materials
Applications: Advantose® 100 is a spray-dried maltose powder that provides excellent flow, solubility, & tableting properties for oral dosage formulations. Maltose is well known for its safety & mouthfeel qualities, especially in chewable tablets & lozenges.
Ingredient(s): Maltose Sugar
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
Applications: Diluent, Osmotic Tablets, Sustain Release Agent
Ingredient(s): Polyethylene Oxide
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
Solving Formulation Challenges Using Superior Functional Materials
Applications: Advantose® FS95 spray-dried fructose is coprocessed with a small quantity of starch, which results in a highly compressible excipient for pharmaceutical, nutraceutical, and chewable vitamin applications.
Ingredient(s): Fructose, Starch
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
Applications: Polysorbate 80 in dry powder form
Ingredient(s): Magnesium aluminium silicate, Polysorbate 80
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Solubilizer in powder form, used in directly compressible dosage forms, Wet granulation, added during lubrication stage
Solving Formulation Challenges Using Superior Functional Materials
Applications: Compressol® SM polyol drug delivery system is a directly compressible platform consisting of mannitol and sorbitol. It assists the formulator with high active-loading formulations and difficult-to-compress actives.
Ingredient(s): Mannitol, Sorbitol
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
Applications: Polyoxyl 40 hydrogenated castor oil In dry powder form
Ingredient(s): MAGNESIUM ALUMINOMETASILICATE, Polyoxyl 40 Hydrogenated Castor Oil
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Solubilizer in powder form, used in Directly compressible dosage forms, Wet granulation, added during lubrication stage
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Applications: Controlled Release, Direct Compression,Wet Granulation,Tablet Coating, Liquid Solutions and Suspensions
Ingredient(s): Hydroxypropyl Methylcellulose
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
Solving Formulation Challenges Using Superior Functional Materials
Applications: Mannogem Mannitol products dissolve rapidly and can increase the rate of tablet disintegration and drug release. They can help accelerate tablet disintegration and subsequent drug dissolution.
Ingredient(s): Mannitol
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
Applications: Direct Compression, Dry Granulation
Ingredient(s): Dibasic Calcium Phosphate, Microcrystalline Cellulose, Silicon Dioxide, Starch
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: For small dose API and large dose API with good compressibility.
Solving Formulation Challenges Using Superior Functional Materials
Applications: Mannogem Mannitol products dissolve rapidly and can increase the rate of tablet disintegration and drug release. They can help accelerate tablet disintegration and subsequent drug dissolution.
Ingredient(s): Mannitol
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
Applications: Direct Compression for pH sensitive APIs
Ingredient(s): Corn Starch, Pregelatinized, Microcrystalline Cellulose, Sodium Starch Glycolate
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Microcrystalline Cellulose, Light Magnesium Oxide, Sodium Starch Glycolate, Pregelatinized Starch, Maize Starch
Applications: Direct compression for moisture sensitive APIs
Ingredient(s): Crospovidone, Microcrystalline Cellulose, Povidone 30, Silicon Dioxide
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Microcrystalline Cellulose, Colloidal Silicon Dioxide, Povidone K30 and Crospovidone
Applications: Direct compression for moisture sensitive APIs
Ingredient(s): Microcrystalline Cellulose, Povidone 30, Silicon Dioxide, Sodium Starch Glycolate
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Microcrystalline Cellulose, Colloidal Silicon Dioxide, Povidone K30 and Sodium Starch Glycolate
Applications: Direct Compression for pH sensitive APIs
Ingredient(s): Crospovidone, Hydroxypropyl Cellulose, Mannitol
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Mannitol, Light Magnesium Oxide, Hydroxy Propyl Cellulose and Crospovidone
Applications: Direct compression for modified release dosage forms
Ingredient(s): EthylCellulose, Hydroxypropyl Cellulose, Hydroxypropyl Methyl Cellulose, Magnesium Stearate, Microcrystalline Cellulose, Silicon Dioxide, Starch, Talc Excipient
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Microcrystalline Cellulose, Ethylcellulose , Hydroxypropyl methyl cellulose K4M, Hydroxypropyl Cellulose, Colloidal Silicon Dioxide, Maize Starch, Magnesium Stearate and Talc
Applications: Direct compression for modified release dosage forms
Ingredient(s): EthylCellulose, Hydroxypropyl Cellulose, Hydroxypropyl Methyl Cellulose, Magnesium Stearate, Microcrystalline Cellulose, Silicon Dioxide
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Microcrystalline Cellulose, Ethylcellulose, Hydroxypropyl methyl cellulose K100Microcrystalline Cellulose, Ethylcellulose, Hydroxypropyl methyl cellulose K100M, Hydroxypropyl Cellulose, Colloidal Silicon Dioxide and Magnesium StearateM, Hydroxypropyl Cell
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Applications: Dry binder & fast disintegrant, suitable for small tablets and ODTs, providing pleasant mouthfeel due to finer particles.
Ingredient(s): Polyvinylpyrrolidone Crosslinked
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: HiCel SMCC has unique combination which result in optimum compaction & superior flow properties.
Ingredient(s): Microcrystalline Cellulose, Silicon Dioxide
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: HiCellac 100 is used in direct compression, dry granulation & capsule filling, suitable for low dose formulations where API content uniformity is critical. It also provides excellent compaction properties & tablet hardness.
Ingredient(s): Lactose Monohydrate, Microcrystalline Cellulose
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: Wetting agent, reducing disintegration time, direct compression, Hydrophilic lubricant, effervescent tablets.
Ingredient(s): Sodium Lauryl Sulfate
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: HiCel acts as a strong & dry binder. It facilitates low tablet friability & promotes rapid tablet disintegration.
Ingredient(s): Microcrystalline Cellulose
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: Tablets made from these granules are typically easily disintegrated using conventional super disintegrates even when hard tablets are compressed.
Ingredient(s): Microcrystalline Cellulose
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: AceCel is suitable for majority of the directly compressible actives, combines good flow and high compressibility.
Ingredient(s): Microcrystalline Cellulose
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: The plastic defamation characteristics of MCC 102 type mean that very hard tablets can be produced at light compaction forces, extending tooling lifetime and solving problems with poorly compressible actives.
Ingredient(s): Microcrystalline Cellulose
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: Use in a wide range of oral applications such as wet or dry granulation, excipient of choice for flash release forms.
Ingredient(s): Mannitol
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Available in different particle size as 25.µ, 50.µ, 180.µ
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Applications: Lactose is widely used as a filler and diluent in tablets and capsules, and to a more limited extent in lyophilized products and infant formulas.
Ingredient(s): Lactose Monohydrate
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: Lactose monohydrate is typically used for wet or dry granulation. During wet granulation, liquid binders or adhesives are added to the lactose and active mixture, usually by blending.
Ingredient(s): Lactose Monohydrate
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Milled; Also Available as Microlex® LCM 180.m, Microlex® LCM 200.m
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Applications: It is also suitable for both wet granulation and direct compression methods of tablet production. Microlex® crystalline grades are used in wet granulation and the spray dried forms are used in direct compression.
Ingredient(s): Lactose Monohydrate
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Sieved; Also Available as Microlex® LCM 180.s, Microlex® LCM 220.s
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Applications: It is also suitable for both wet granulation and direct compression methods of tablet production. Microlex® crystalline grades are used in wet granulation and the spray dried forms are used in direct compression.
Ingredient(s): Anhydrous Lactose
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Milled; Also Available as Microlex® LCA 120.m, Microlex® LCA 200.m
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Applications: Carbopol® 71G NF polymer is widely used in oral solid dose applications.The unique feature of this polymer is its granular form due to which it is used in direct compression formulations. The residual solvent in Carbopol 71G NF is Ethyl acetate.
Ingredient(s): Carbomer Homopolymer Type A
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Viscosity, cP (0.5 wt% at pH 7.5) - 4,000 - 11,000
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Applications: Wet Granulation and Direct Compression
Ingredient(s): Polacrilin Potassium
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: Wet Granulation and Direct Compression
Ingredient(s): Polacrilin Potassium
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: Solubilizer
Ingredient(s): Magnesium Aluminometasilicate, Polysorbate 80
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Solubilizer in powder form; EXCiPACT
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Applications: Solubilizer
Ingredient(s): Polyoxyl 40 hydrogenated castor oil
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Solubilizer in powder form; EXCiPACT
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Applications: Lipophilic lubricant, for sensitive acidic APIs, sustained release melt coating. Used as consistency factor to enhance the viscosity of topical formulations.
Ingredient(s): Hydrogenated Castor Oil
Dosage Form: Tablet
Category: Direct Compression
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