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Anhydrous Lactose
Carbomer Homopolymer Type A
Crospovidone
Fructose
Hydrogenated Castor Oil
Hydroxypropyl Methylcellulose
Lactose Monohydrate
Lauryl Sulfate
Maltose Sugar
Mannitol
Microcrystalline Cellulose
Microprilled Poloxamer
Native & Pregelatinized Corn Starch
Polacrilin Potassium
Polyoxyl 40 hydrogenated castor oil
Polysorbate 80
Polyvinylpyrrolidone Crosslinked
Povidone
Sodium Lauryl Sulfate
Stearic Acid
Stearyl Alcohol
Vinylpyrrolidone-Vinyl Acetate
Vinylpyrrolidone-Vinyl Acetate Copolymer
BASF
Corel Pharma Chem
DFE Pharma
Lubrizol Life Science Health
Microlex e.U
SPI Pharma
Seppic
Sigachi Industries
The Dow Chemical Company
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Global leader in Excipient Solutions
Applications: Pharmacel® 102 has good flow properties enabling high speed direct compression tableting. It is a ideal choice for direct compression & dry granulation formulations and it also has some lubrication properties for smooth tableting experience.
Ingredient(s): Microcrystalline Cellulose
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Density- Tapped density- 440 g/l, Bulk density- 310 g/l; Particle size- D10- 40 ?m, D50- 90 ?m, D90-180 ?m; Hausner ratio-1,42
Solving Formulation Challenges Using Superior Functional Materials
Applications: Advantol® 300 Polyol Drug Delivery system is a directly compressible paltform to create soft chew or soft melt oral dosage forms.It is a robust system that allows fast product development.
Ingredient(s): Mannitol
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
Global leader in Excipient Solutions
Applications: SuperTab® 11SD offers the best compactability of all grades of lactose, and it is well suited to direct compression applications. Due to the low moisture content, it is used in the formulations containing moisture sensitive drugs.
Ingredient(s): Anhydrous Lactose
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Density- Tapped density- 906 g/l, Bulk density- 722 g/l; Particle size- D10-15 ?m, D50- 170 ?m, D90- 340 ?m; Hausner ratio-1,25
Solving Formulation Challenges Using Superior Functional Materials
Applications: Advantose® 100 is a spray-dried maltose powder that provides excellent flow, solubility, & tableting properties for oral dosage formulations. Maltose is well known for its safety & mouthfeel qualities, especially in chewable tablets & lozenges.
Ingredient(s): Maltose Sugar
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: Dry binder & fast disintegrant, suitable for small tablets and ODTs, providing pleasant mouthfeel due to finer particles.
Ingredient(s): Polyvinylpyrrolidone Crosslinked
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
Solving Formulation Challenges Using Superior Functional Materials
Applications: Advantose® FS95 spray-dried fructose is coprocessed with a small quantity of starch, which results in a highly compressible excipient for pharmaceutical, nutraceutical, and chewable vitamin applications.
Ingredient(s): Fructose, Starch
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
Solving Formulation Challenges Using Superior Functional Materials
Applications: Compressol® SM polyol drug delivery system is a directly compressible platform consisting of mannitol and sorbitol. It assists the formulator with high active-loading formulations and difficult-to-compress actives.
Ingredient(s): Mannitol, Sorbitol
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: Controlled Release, Direct Compression,Wet Granulation,Tablet Coating, Liquid Solutions and Suspensions
Ingredient(s): Hydroxypropyl Methylcellulose
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
Solving Formulation Challenges Using Superior Functional Materials
Applications: Mannogem Mannitol products dissolve rapidly and can increase the rate of tablet disintegration and drug release. They can help accelerate tablet disintegration and subsequent drug dissolution.
Ingredient(s): Mannitol
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
Solving Formulation Challenges Using Superior Functional Materials
Applications: Mannogem Mannitol products dissolve rapidly and can increase the rate of tablet disintegration and drug release. They can help accelerate tablet disintegration and subsequent drug dissolution.
Ingredient(s): Mannitol
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: Wetting agent, reducing disintegration time, direct compression, Hydrophilic lubricant, effervescent tablets.
Ingredient(s): Sodium Lauryl Sulfate
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: Lipophilic lubricant, for sensitive acidic APIs, sustained release melt coating. Used as consistency factor to enhance the viscosity of topical formulations.
Ingredient(s): Hydrogenated Castor Oil
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: Lipophilic lubricant, for sensitive acidic APIs, Structure-building consistency factor for semi-solids, Viscosity regulator.
Ingredient(s): Stearyl Alcohol
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: Lipophilic lubricant, especially for sensitive acidic APIs. Matrix forming agent in sustained-release dosage forms, emulsifying and solubilizing agent in topical formulations and hardening agent in glycerin suppositories
Ingredient(s): Palmitic Acid, Stearic Acid
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: Ready-to-use direct compression solution for tablets.
Ingredient(s): Crospovidone, Lactose, Povidone
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: Ready-to-use direct compression solution for lozenges, chewables and effervescent tablets.
Ingredient(s): Lactose, Povidone
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: Maximum disintegration
Ingredient(s): Polyvinylpyrrolidone Crosslinked
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: Balance of strong disintegration and optimal surface homogeneity.
Ingredient(s): Polyvinylpyrrolidone Crosslinked
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: Roller compaction & direct compression including slight disintegration functionality, Reduces sedimentation in suspensions. Solubilizer in transdermal patches.
Ingredient(s): Polyvinylpyrrolidone Crosslinked
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: For non-erodible matrices using direct compression, Controlled release matrix. Matrix former in transdermal patches and topical films.
Ingredient(s): Hydrated Silica, Lauryl Sulfate, Polyvinyl Acetate, Povidone
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: Dry binder in tablets, capsules and granules, as a film-forming agent in tablet coatings and subcoatings, and as a film-forming agent in topical sprays. Widely used in HME processes.
Ingredient(s): Vinylpyrrolidone-Vinyl Acetate
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: Binder with fine particle size for roller compaction & direct compression
Ingredient(s): Vinylpyrrolidone-Vinyl Acetate Copolymer
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: Dissolution enhancer, lubricant & wetting agent, Hydrophilic lubricant, effervescent tablets.
Ingredient(s): Microprilled Poloxamer
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: Dissolution enhancer, lubricant & wetting agent, Hydrophilic lubricant, effervescent tablets.
Ingredient(s): Microprilled Poloxamer
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: HiCel SMCC has unique combination which result in optimum compaction & superior flow properties.
Ingredient(s): Microcrystalline Cellulose, Silicon Dioxide
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: HiCellac 100 is used in direct compression, dry granulation & capsule filling, suitable for low dose formulations where API content uniformity is critical. It also provides excellent compaction properties & tablet hardness.
Ingredient(s): Lactose Monohydrate, Microcrystalline Cellulose
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: HiCel acts as a strong & dry binder. It facilitates low tablet friability & promotes rapid tablet disintegration.
Ingredient(s): Microcrystalline Cellulose
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: Tablets made from these granules are typically easily disintegrated using conventional super disintegrates even when hard tablets are compressed.
Ingredient(s): Microcrystalline Cellulose
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: The plastic defamation characteristics of MCC 102 type mean that very hard tablets can be produced at light compaction forces, extending tooling lifetime and solving problems with poorly compressible actives.
Ingredient(s): Microcrystalline Cellulose
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: AceCel is suitable for majority of the directly compressible actives, combines good flow and high compressibility.
Ingredient(s): Microcrystalline Cellulose
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: Use in a wide range of oral applications such as wet or dry granulation, excipient of choice for flash release forms.
Ingredient(s): Mannitol
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Available in different particle size as 25.µ, 50.µ, 180.µ
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Applications: Lactose is widely used as a filler and diluent in tablets and capsules, and to a more limited extent in lyophilized products and infant formulas.
Ingredient(s): Lactose Monohydrate
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: Lactose monohydrate is typically used for wet or dry granulation. During wet granulation, liquid binders or adhesives are added to the lactose and active mixture, usually by blending.
Ingredient(s): Lactose Monohydrate
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Milled; Also Available as Microlex® LCM 180.m, Microlex® LCM 200.m
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Applications: It is also suitable for both wet granulation and direct compression methods of tablet production. Microlex® crystalline grades are used in wet granulation and the spray dried forms are used in direct compression.
Ingredient(s): Lactose Monohydrate
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Sieved; Also Available as Microlex® LCM 180.s, Microlex® LCM 220.s
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Applications: It is also suitable for both wet granulation and direct compression methods of tablet production. Microlex® crystalline grades are used in wet granulation and the spray dried forms are used in direct compression.
Ingredient(s): Anhydrous Lactose
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Milled; Also Available as Microlex® LCA 120.m, Microlex® LCA 200.m
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Applications: Carbopol® 71G NF polymer is widely used in oral solid dose applications.The unique feature of this polymer is its granular form due to which it is used in direct compression formulations. The residual solvent in Carbopol 71G NF is Ethyl acetate.
Ingredient(s): Carbomer Homopolymer Type A
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Viscosity, cP (0.5 wt% at pH 7.5) - 4,000 - 11,000
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Applications: Wet Granulation and Direct Compression
Ingredient(s): Polacrilin Potassium
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: Wet Granulation and Direct Compression
Ingredient(s): Polacrilin Potassium
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Not Available
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Applications: Solubilizer
Ingredient(s): Magnesium Aluminometasilicate, Polysorbate 80
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Solubilizer in powder form; EXCiPACT
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Applications: Solubilizer
Ingredient(s): Polyoxyl 40 hydrogenated castor oil
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: Solubilizer in powder form; EXCiPACT
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Applications: Capsule Filling, Direct Compression, Binding, Disintegration
Ingredient(s): Native & Pregelatinized Corn Starch
Dosage Form: Tablet
Category: Direct Compression
Technical Specifications: EXCiPACT
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