The abundance of proteins in a sample of interest can vary by orders of magnitude, and often the most interesting proteins are present at very low levels. Discovery proteomics places high demands on separation, sensitivity, and informatics.
Proteome Sciences has developed an analytical proteomic pipeline to provide broad biological context of targets and drug mechanisms based on unbiased analysis of protein expression and phosphorylation (SysQuant®), statistical data modeling (FeaST) and a novel functional analysis tool (FAT).
SCLS is Shantani's proprietary and most comprehensive method for target identification, validation and for determination of the mechanism of action.
Agilent provides a comprehensive portfolio of software tools to support both discovery and targeted proteomics workflows. Our integrated solutions enable you to perform protein database searches and quality assessments, apply previous results to new experiments, create MRM methods, and build
Precision Medicine requires close integration between targeted drugs and biomarkers providing early and actionable clinical information. Ideally, such biomarkers are mechanistically related to disease and treatment mechanisms, predictive of outcome and measurable in accessible samples, typically