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                          Therapeutic Area by Lead Product

                          Study Phase by Lead Product

                          Company by Lead Product

                          Top Deals by Deal Size (USD bn)

                          01

                          Details : ABBV-RGX-314 is a drug candidate, which is currently being evaluated in phase II/ phase III clinical studies for the treatment of Macular Degeneration.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          January 12, 2021

                          Lead Product(s) : ABBV-RGX-314

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Regenxbio

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Abbvie Company Banner

                          02

                          BioJapan
                          Not Confirmed
                          BioJapan
                          Not Confirmed

                          Details : Travoprost is a HPAPI drug candidate, which is currently being evaluated in Phase II/ Phase III clinical studies for the treatment of Glaucoma.

                          Product Name : Undisclosed

                          Product Type : HPAPI

                          Upfront Cash : Inapplicable

                          July 20, 2025

                          Lead Product(s) : Travoprost

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          BioJapan
                          Not Confirmed
                          BioJapan
                          Not Confirmed

                          Details : NCX 470 is a novel NO-donating bimatoprost eye drop which is currently under development for the lowering of IOP in patients with open-angle glaucoma or ocular hypertension.

                          Product Name : Undisclosed

                          Product Type : HPAPI

                          Upfront Cash : Inapplicable

                          May 14, 2025

                          Lead Product(s) : Bimatoprost

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          BioJapan
                          Not Confirmed
                          BioJapan
                          Not Confirmed

                          Details : EYE103 is a Other Large Molecule drug candidate, which is currently being evaluated in phase II/ phase III clinical studies for the treatment of Macular Edema.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          May 04, 2025

                          Lead Product(s) : EYE103

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          BioJapan
                          Not Confirmed
                          BioJapan
                          Not Confirmed

                          Details : Under the agreement, Lomb has the option to acquire InflammX Therapeutics and its ophthalmic product portfolio, including Xiflam (tonabersat) for the treatment of wet AMD.

                          Product Name : Xiflam

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          January 10, 2025

                          Lead Product(s) : Tonabersat

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Bausch & Lomb Incorporated

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          06

                          BioJapan
                          Not Confirmed
                          BioJapan
                          Not Confirmed

                          Details : The proceeds from the financing will support the ongoing clinical development of AVD-104, which is being evaluated for the treatment of geographic atrophy.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Undisclosed

                          January 07, 2025

                          Lead Product(s) : AVD-104

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Omega Funds

                          Deal Size : $207.5 million

                          Deal Type : Series C Financing

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                          07

                          BioJapan
                          Not Confirmed
                          BioJapan
                          Not Confirmed

                          Details : ABY-035 (izokibep) is a small protein therapeutic designed to inhibit IL-17A with high potency. It is being evaluated for the treatment of non-infectious, non-anterior uveitis.

                          Product Name : Undisclosed

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          December 10, 2024

                          Lead Product(s) : Izokibep

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          BioJapan
                          Not Confirmed
                          BioJapan
                          Not Confirmed

                          Details : Restoret (MK-3000), a first-in-class tetravalent, tri-specific antibody and late-phase candidate for diabetic macular edema and neovascular age-related macular degeneration.

                          Product Name : Restoret

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          September 04, 2024

                          Lead Product(s) : EYE103

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          BioJapan
                          Not Confirmed
                          BioJapan
                          Not Confirmed

                          Details : EYE103 is a Other Large Molecule drug candidate, which is currently being evaluated in phase II/ phase III clinical studies for the treatment of Macular Edema.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          August 26, 2024

                          Lead Product(s) : EYE103

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          BioJapan
                          Not Confirmed
                          BioJapan
                          Not Confirmed

                          Details : AZR-MD-001 is an ophthalmic ointment, applied directly to the meibomian glands. It is under clinical development for the patients with Contact Lens Discomfort & Meibomian Gland Dysfunction.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          June 04, 2024

                          Lead Product(s) : Selenium Sulfide

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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