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    [{"orgOrder":0,"company":"RiboX Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Dental and Oral Health","country":"CHINA","productType":"Oligonucleotide","year":"2025","type":"Inapplicable","leadProduct":"RXRG001","moa":"hAQP1 overexpression","graph1":"Dental and Oral Health","graph2":"Phase I\/ Phase II","graph3":"RiboX Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Dental & Oral Health","amount2New":0,"dosageForm":"Intraductal Injection","sponsorNew":"RiboX Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"RiboX Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"MeiraGTx","sponsor":"Sanofi","pharmaFlowCategory":"D","therapeuticArea":"Dental and Oral Health","country":"U.S.A","productType":"Other Large Molecule","year":"2023","type":"Financing","leadProduct":"AAV-AQP1","moa":"Undisclosed","graph1":"Dental and Oral Health","graph2":"Phase I\/ Phase II","graph3":"MeiraGTx","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Dental & Oral Health","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"MeiraGTx \/ Sanofi","highestDevelopmentStatusID":"7","companyTruncated":"MeiraGTx \/ Sanofi"}]

    Find Clinical Drug Development Pipelines & Deals | PipelineProspector

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                            01

                            RiboX Therapeutics

                            China arrow
                            AACR Annual meeting
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                            RiboX Therapeutics

                            China arrow
                            AACR Annual meeting
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                            Lead Product(s) : RXRG001

                            Therapeutic Area : Dental and Oral Health

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            RiboX Announces First Patient Dosed in Phase I/IIa Clinical Trial of RXRG001

                            Details : RXRG001 is an AQP1 modulator, circular RNA, which is currently being evaluated for the treatment of patients with radiation-induced-xerostomia (RIX) and hyposalivation.

                            Product Name : RXRG001

                            Product Type : Oligonucleotide

                            Upfront Cash : Inapplicable

                            March 09, 2025

                            Lead Product(s) : RXRG001

                            Therapeutic Area : Dental and Oral Health

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            MeiraGTx

                            U.S.A arrow
                            AACR Annual meeting
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                            MeiraGTx

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                            Lead Product(s) : AAV-AQP1

                            Therapeutic Area : Dental and Oral Health

                            Study Phase : Phase I/ Phase II

                            Sponsor : Sanofi

                            Deal Size : $30.0 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            MeiraGTx Announces $30 Million Strategic Investment from Sanofi; Company Pursuing Multiple Additional Strategi...

                            Details : Sanofi will receive a right of first negotiation for the use of MeiraGTx’s Riboswitch gene regulation technology for certain Immunology and Inflammation and CNS targets, including AAV-AQP1, a gene therapy for xerostomia caused by Sjogren's syndrome.

                            Product Name : AAV-AQP1

                            Product Type : Other Large Molecule

                            Upfront Cash : Undisclosed

                            October 30, 2023

                            Lead Product(s) : AAV-AQP1

                            Therapeutic Area : Dental and Oral Health

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Sanofi

                            Deal Size : $30.0 million

                            Deal Type : Financing

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