[{"orgOrder":0,"company":"Halozyme Therapeutics","sponsor":"Horizon Therapeutics","pharmaFlowCategory":"D","amount":"$190.0 million","upfrontCash":"$30.0 million","newsHeadline":"Horizon Therapeutics plc and Halozyme Therapeutics, Inc. Enter Global Collaboration and License Agreement for ENHANZE\u00ae Technology","therapeuticArea":"Immunology","highestDevelopmentStatus":"Phase IV","country":"","productType":"Large molecule","productStatus":"Approved","date":"November 2020","year":"2020","type":"Collaboration","leadProduct":"Teprotumumab","moa":"IGF-1R","url1":"","url2":"","graph1":"Immunology","graph2":"Phase IV","graph3":"Halozyme Therapeutics","amount2":0.19,"therapeuticAreaNew":"Immunology","highestDevelopmentStatusNew":"Phase IV","highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Immunology","productSubType":"","amount2New":0.19,"dosageForm":"Intravenous Injection","sponsorNew":"Halozyme Therapeutics \/ Horizon Therapeutics","highestDevelopmentStatusID":"11","companyTruncated":"Halozyme T.."},{"orgOrder":0,"company":"Pfizer Inc","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Pfizer Shares Co-Primary Endpoint Results from Post-Marketing Required Safety Study of Xeljanz\u00ae in Rheumatoid Arthritis Patients","therapeuticArea":"Immunology","highestDevelopmentStatus":"Phase IV","country":"","productType":"Small molecule","productStatus":"Approved","date":"January 2021","year":"2021","type":"Not Applicable","leadProduct":"Tofacitinib Citrate","moa":"JAK","url1":"","url2":"","graph1":"Immunology","graph2":"Phase IV","graph3":"Pfizer Inc","amount2":0,"therapeuticAreaNew":"Immunology","highestDevelopmentStatusNew":"Phase IV","highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Immunology","productSubType":"Small molecule","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Pfizer Inc \/ Not Applicable","highestDevelopmentStatusID":"11","companyTruncated":"Pfizer Inc.."},{"orgOrder":0,"company":"Pfizer Inc","sponsor":"Not Applicable","pharmaFlowCategory":"DU","amount":"Not Applicable","upfrontCash":"Not Applicable","newsHeadline":"Health Canada has Initiated a Safety Review On Xeljanz and Xeljanz XR (Tofacitinib), Used to Treat Arthritis and Ulcerative Colitis","therapeuticArea":"Immunology","highestDevelopmentStatus":"Phase IV","country":"","productType":"Small molecule","productStatus":"Approved","date":"April 2021","year":"2021","type":"Not Applicable","leadProduct":"Tofacitinib Citrate","moa":"JAK","url1":"","url2":"","graph1":"Immunology","graph2":"Phase IV","graph3":"Pfizer Inc","amount2":0,"therapeuticAreaNew":"Immunology","highestDevelopmentStatusNew":"Phase IV","highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Immunology","productSubType":"Small molecule","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Pfizer Inc \/ Not Applicable","highestDevelopmentStatusID":"11","companyTruncated":"Pfizer Inc.."}]

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                          01

                          26th North American ISSX
                          Not Confirmed
                          26th North American ISSX
                          Not Confirmed

                          Details : HADLIMA (Adalimumab-bwwd) is a biosimilar product of HUMIRA®, formulated for the treatment of rheumatoid arthritis (RA), polyarticular juvenile idiopathic arthritisetc. The drug bind specifically to TNF-...

                          Product Name : Hadlima

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          August 01, 2023

                          Lead Product(s) : Adalimumab-bwwd

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase IV

                          Partner/Sponsor/Collaborator : Organon

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          26th North American ISSX
                          Not Confirmed
                          26th North American ISSX
                          Not Confirmed

                          Details : Tepezza (teprotumumab-trbw) binds to insulin-like growth factor-1 receptor (IGF-1R) and blocks its activation and signaling. It is being investigated in patients with thyroid eye disease.

                          Product Name : Tepezza

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          April 10, 2023

                          Lead Product(s) : Teprotumumab

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase IV

                          Partner/Sponsor/Collaborator : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          26th North American ISSX
                          Not Confirmed
                          26th North American ISSX
                          Not Confirmed

                          Details : TREMFYA (guselkumab) is a fully human monoclonal antibody that selectively binds to the p19 subunit of IL-23 and inhibits its interaction with the IL-23 receptor. IL-23 is an important driver of the patho...

                          Product Name : Tremfya

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          November 10, 2022

                          Lead Product(s) : Guselkumab

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase IV

                          Partner/Sponsor/Collaborator : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          26th North American ISSX
                          Not Confirmed
                          26th North American ISSX
                          Not Confirmed

                          Details : Tepezza, (teprotumumab-trbw) first medicine approved by FDA for treatment of TED, among thousands of patients included in this 19-month new post-marketing Safety analysis, approximately 10% of all cases r...

                          Product Name : Tepezza

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          February 15, 2022

                          Lead Product(s) : Teprotumumab

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase IV

                          Partner/Sponsor/Collaborator : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          26th North American ISSX
                          Not Confirmed
                          26th North American ISSX
                          Not Confirmed

                          Details : Among those treated with OLUMIANT, the overall incidence rate of adverse events per 100 patient years of exposure was 22.6, and the incidence rate of serious adverse events was 7.4. Incidence rates remain...

                          Product Name : Olumiant

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          November 09, 2021

                          Lead Product(s) : Baricitinib

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase IV

                          Partner/Sponsor/Collaborator : Incyte Corporation

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          26th North American ISSX
                          Not Confirmed
                          26th North American ISSX
                          Not Confirmed

                          Details : Health Canada is informing Canadians and health care professionals that it is conducting a safety review of Xeljanz and Xeljanz XR (tofacitinib) after a clinical trial identified an increased risk of seri...

                          Product Name : Xeljanz

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          April 06, 2021

                          Lead Product(s) : Tofacitinib Citrate

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase IV

                          Partner/Sponsor/Collaborator : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          26th North American ISSX
                          Not Confirmed
                          26th North American ISSX
                          Not Confirmed

                          Details : The co-primary endpoints of this study were non-inferiority of tofacitinib compared to TNFi in regard to major adverse cardiovascular events (MACE) and malignancies (excluding non-melanoma skin cancer (NM...

                          Product Name : Xeljanz

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          January 31, 2021

                          Lead Product(s) : Tofacitinib Citrate

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase IV

                          Partner/Sponsor/Collaborator :