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19 Dec 2025
// GLOBENEWSWIRE
https://www.globenewswire.com/news-release/2025/12/19/3208323/0/en/Alvotech-and-Teva-Secure-U-S-Settlement-Date-for-AVT06-a-Proposed-Biosimilar-to-Eylea.html

10 Dec 2025
// BIOSPACE
https://www.biospace.com/business/regeneron-climbs-back-after-a-year-of-regulatory-manufacturing-misery

08 Dec 2025
// FIERCE PHARMA
https://www.fiercepharma.com/pharma/ash-regeneron-does-subtraction-bids-move-bispecifics-earlier-treatment-blood-cancers

07 Dec 2025
// GLOBENEWSWIRE
https://www.globenewswire.com/news-release/2025/12/07/3201147/0/en/Lynozyfic-linvoseltamab-Monotherapy-in-Newly-Diagnosed-Multiple-Myeloma-NDMM-Shows-Impressive-Responses-Supporting-Rationale-as-a-Potential-Foundation-in-Frontline-Treatment.html

01 Dec 2025
// PRESS RELEASE
https://investor.regeneron.com/news-releases/news-release-details/regeneron-and-tessera-therapeutics-jointly-develop-tsra-196

26 Nov 2025
// PRESS RELEASE
https://www.sanofi.com/en/media-room/press-releases/2025/2025-11-25-06-00-00-3194015
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Kevzara (Sarilumab) is a antibody drug candidate, which is currently being evaluated in Phase IV clinical studies for the treatment of Polymyalgia Rheumatica.
Lead Product(s): Sarilumab,Inapplicable
Therapeutic Area: Musculoskeletal Brand Name: Kevzara
Study Phase: Phase IVProduct Type: Antibody, Unconjugated
Recipient: Sanofi
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable December 16, 2025

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Lead Product(s) : Sarilumab,Inapplicable
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase IV
Recipient : Sanofi
Deal Size : Inapplicable
Deal Type : Inapplicable
Sarilumab Efficacy and Safety in Adults With Early Polymyalgia Rheumatica
Details : Kevzara (Sarilumab) is a antibody drug candidate, which is currently being evaluated in Phase IV clinical studies for the treatment of Polymyalgia Rheumatica.
Product Name : Kevzara
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
December 16, 2025

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Oxaliplatin is a Cytotoxic Drug drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Colorectal Neoplasms.
Lead Product(s): Oxaliplatin,Capecitabine,Cemiplimab,Fianlimab,REGN7075
Therapeutic Area: Oncology Brand Name: Undisclosed
Study Phase: Phase IIProduct Type: Cytotoxic Drug
Recipient: Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable December 15, 2025

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Lead Product(s) : Oxaliplatin,Capecitabine,Cemiplimab,Fianlimab,REGN7075
Therapeutic Area : Oncology
Highest Development Status : Phase II
Recipient : Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Oxaliplatin is a Cytotoxic Drug drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Colorectal Neoplasms.
Product Name : Undisclosed
Product Type : Cytotoxic Drug
Upfront Cash : Inapplicable
December 15, 2025

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ALN-ANG3 is a Oligonucleotide drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Diabetic Nephropathies.
Lead Product(s): ALN-ANG3,Evinacumab
Therapeutic Area: Nephrology Brand Name: Undisclosed
Study Phase: Phase IIProduct Type: Oligonucleotide
Sponsor: Undisclosed
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable December 09, 2025

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Lead Product(s) : ALN-ANG3,Evinacumab
Therapeutic Area : Nephrology
Highest Development Status : Phase II
Partner/Sponsor/Collaborator : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ALN-ANG3 is a Oligonucleotide drug candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Diabetic Nephropathies.
Product Name : Undisclosed
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
December 09, 2025

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The collaboration aims to advance TSRA-196, a cell & gene therapy, targeting A1AT for Alpha-1 Antitrypsin Deficiency (AATD).
Lead Product(s): TSRA-196,Inapplicable
Therapeutic Area: Genetic Disease Brand Name: Undisclosed
Study Phase: Phase I/ Phase IIProduct Type: Cell & Gene Therapy
Recipient: Tessera Therapeutics
Deal Size: $275.0 million Upfront Cash: $150.0 million
Deal Type: Collaboration December 01, 2025

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Lead Product(s) : TSRA-196,Inapplicable
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I/ Phase II
Recipient : Tessera Therapeutics
Deal Size : $275.0 million
Deal Type : Collaboration
Regeneron, Tessera to Develop TSRA-196 Gene Editing Therapy for AATD
Details : The collaboration aims to advance TSRA-196, a cell & gene therapy, targeting A1AT for Alpha-1 Antitrypsin Deficiency (AATD).
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : $150.0 million
December 01, 2025

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Cemiplimab is a antibody candidate, which is currently being evaluated in Phase I/ Phase II clinical studies for the treatment of Carcinoma, Basal Cell.
Lead Product(s): Cemiplimab,Imiquimod
Therapeutic Area: Oncology Brand Name: Undisclosed
Study Phase: Phase I/ Phase IIProduct Type: Antibody, Unconjugated
Recipient: Instituto Oncológico Dr. Rosell
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable November 26, 2025

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Lead Product(s) : Cemiplimab,Imiquimod
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Recipient : Instituto Oncológico Dr. Rosell
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Cemiplimab is a antibody candidate, which is currently being evaluated in Phase I/ Phase II clinical studies for the treatment of Carcinoma, Basal Cell.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
November 26, 2025

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Dupilumab, an unconjugated antibody targeting Interleukin-4 receptor subunit alpha, shows promise in treating undisclosed Key Focus Area.
Lead Product(s): Dupilumab,Inapplicable
Therapeutic Area: Immunology Brand Name: Dupixent
Study Phase: Approved FDFProduct Type: Antibody, Unconjugated
Sponsor: Sanofi
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable November 25, 2025

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Lead Product(s) : Dupilumab,Inapplicable
Therapeutic Area : Immunology
Highest Development Status : Approved FDF
Partner/Sponsor/Collaborator : Sanofi
Deal Size : Inapplicable
Deal Type : Inapplicable
Dupixent® Approved as First Targeted Medicine in EU for Chronic Spontaneous Urticaria
Details : Dupilumab, an unconjugated antibody targeting Interleukin-4 receptor subunit alpha, shows promise in treating undisclosed Key Focus Area.
Product Name : Dupixent
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
November 25, 2025

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REGN4461 (Mibavademab) is an antibody candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Functional Hypothalamic Amenorrhea.
Lead Product(s): Mibavademab,Inapplicable
Therapeutic Area: Endocrinology Brand Name: REGN4461
Study Phase: Phase IIProduct Type: Antibody, Unconjugated
Sponsor: Undisclosed
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable November 19, 2025

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Lead Product(s) : Mibavademab,Inapplicable
Therapeutic Area : Endocrinology
Highest Development Status : Phase II
Partner/Sponsor/Collaborator : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
A Study to Investigate Mibavademab in Adult Women With Functional Hypothalamic Amenorrhea
Details : REGN4461 (Mibavademab) is an antibody candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Functional Hypothalamic Amenorrhea.
Product Name : REGN4461
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
November 19, 2025

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Aflibercept, a protein targeting vascular endothelial growth factor A and placenta growth factor, shows promise in treating macular edema.
Lead Product(s): Aflibercept,Inapplicable
Therapeutic Area: Ophthalmology Brand Name: Eylea HD
Study Phase: Approved FDFProduct Type: Protein
Sponsor: Undisclosed
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable November 19, 2025

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Lead Product(s) : Aflibercept,Inapplicable
Therapeutic Area : Ophthalmology
Highest Development Status : Approved FDF
Partner/Sponsor/Collaborator : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Fda Approves Eylea Hd® 8 mg for Macular Edema and Monthly Dosing
Details : Aflibercept, a protein targeting vascular endothelial growth factor A and placenta growth factor, shows promise in treating macular edema.
Product Name : Eylea HD
Product Type : Protein
Upfront Cash : Inapplicable
November 19, 2025

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Cemiplimab, an antibody targeting PD-1, shows promise in treating cutaneous squamous cell carcinoma (CSCC).
Lead Product(s): Cemiplimab,Inapplicable
Therapeutic Area: Oncology Brand Name: Libtayo
Study Phase: Approved FDFProduct Type: Antibody, Unconjugated
Sponsor: Undisclosed
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable November 19, 2025

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Lead Product(s) : Cemiplimab,Inapplicable
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Partner/Sponsor/Collaborator : Undisclosed
Deal Size : Inapplicable
Deal Type : Inapplicable
Libtayo® Approved in EU as First Immunotherapy for Adjuvant Treatment of CSCC
Details : Cemiplimab, an antibody targeting PD-1, shows promise in treating cutaneous squamous cell carcinoma (CSCC).
Product Name : Libtayo
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
November 19, 2025

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Cemiplimab is an antibody candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Mesothelioma, Malignant.
Lead Product(s): Cemiplimab,Fianlimab,Pemetrexed,Cisplatin,Carboplatin
Therapeutic Area: Oncology Brand Name: Undisclosed
Study Phase: Phase IIProduct Type: Antibody, Unconjugated
Recipient: Intergroupe Francophone de Cancerologie Thoracique
Deal Size: Inapplicable Upfront Cash: Inapplicable
Deal Type: Inapplicable November 18, 2025

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Lead Product(s) : Cemiplimab,Fianlimab,Pemetrexed,Cisplatin,Carboplatin
Therapeutic Area : Oncology
Highest Development Status : Phase II
Recipient : Intergroupe Francophone de Cancerologie Thoracique
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Cemiplimab is an antibody candidate, which is currently being evaluated in Phase II clinical studies for the treatment of Mesothelioma, Malignant.
Product Name : Undisclosed
Product Type : Antibody, Unconjugated
Upfront Cash : Inapplicable
November 18, 2025

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