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Details:
The researchers first looked at a fruit fly model of amyloid toxicity, which occurs in neurological diseases when abnormal levels of this naturally occurring protein clump together and disrupt nerve cell function.
Lead Product(s):
Undisclosed
Therapeutic Area: Neurology
Product Name: Undisclosed
Highest Development Status: Discovery
Product Type: Undisclosed
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
September 14, 2022
Details:
The partnership aims to develop novel metabolomic biomarkers, assist in the development of new pathology-based disease classifications, and investigate underlying disease mechanisms of dementia to help discover new relevant drug targets.
Lead Product(s):
Undisclosed
Therapeutic Area: Neurology
Product Name: Undisclosed
Highest Development Status: Discovery
Product Type: Small molecule
Partner/Sponsor/Collaborator:
BioFINDER
Deal Size: Undisclosed
Upfront Cash: Undisclosed
Deal Type: Partnership
September 13, 2022
Details:
The collaboration will focus on the discovery and development of novel AAV capsids for CNS diseases. As a part of the collaboration, Prevail will receive rights to utilize one of Lacerta’s novel AAV capsids for select undisclosed CNS targets.
Lead Product(s):
AAV Capsid-based Therapeutic
Therapeutic Area: Neurology
Product Name: Undisclosed
Highest Development Status: Discovery
Product Type: Cell and Gene therapy
Partner/Sponsor/Collaborator:
Prevail Therapeutics
Deal Size: Undisclosed
Upfront Cash: Undisclosed
Deal Type: Collaboration
August 23, 2022
Details:
The new agreement will leverage Sosei Heptares’ StaR® technology and structure-based drug design (SBDD) platform and AbbVie’s extensive neuroscience and disease area expertise.
Lead Product(s):
Undisclosed
Therapeutic Area: Neurology
Product Name: Undisclosed
Highest Development Status: Discovery
Product Type: Small molecule
Partner/Sponsor/Collaborator:
AbbVie Inc
Deal Size: $1,280.0 million
Upfront Cash: $40.0 million
Deal Type: Collaboration
August 02, 2022
Details:
Under the terms of the agreement, SwanBio will license the FunSel screening platform from Purespring to explore new targets for early-stage pipeline programs. SwanBio will have an option to develop any targets identified and to own and commercialise any molecules developed.
Lead Product(s):
AAV-based Gene Therapy
Therapeutic Area: Neurology
Product Name: Undisclosed
Highest Development Status: Discovery
Product Type: Cell and Gene therapy
Partner/Sponsor/Collaborator:
SwanBio Therapeutics
Deal Size: Undisclosed
Upfront Cash: Undisclosed
Deal Type: Licensing Agreement
July 18, 2022
Details:
In this alliance, MTPC and EditForce aim to create potential novel pharmaceuticals for the specific CNS disease by utilizing the drug R&D. EditForce will proceed with R&D of pharmaceuticals using PPR protein platform technology.
Lead Product(s):
PPR Proteins-Based Therapeutic
Therapeutic Area: Neurology
Product Name: Undisclosed
Highest Development Status: Discovery
Product Type: Large molecule
Partner/Sponsor/Collaborator:
Mitsubishi Tanabe Pharma
Deal Size: $145.7 million
Upfront Cash: Undisclosed
Deal Type: Licensing Agreement
June 27, 2022
Details:
The patent is assigned to IGC and relates to compositions and methods for treating multiple types of seizure disorders and epilepsy in humans and animals, using a combination of the cannabinoid cannabidiol with other compounds.
Lead Product(s):
Cannabinoid,Cannabidiol
Therapeutic Area: Neurology
Product Name: Undisclosed
Highest Development Status: Discovery
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
June 08, 2022
Details:
The strategic collaboration will aim to accelerate drug discovery in neurodegenerative disease, tackling undisclosed targets in a multi-year programme. Denali will be responsible for the further lead optimisation, development, and commercialisation of these molecules.
Lead Product(s):
Undisclosed
Therapeutic Area: Neurology
Product Name: Undisclosed
Highest Development Status: Discovery
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Denali Therapeutics
Deal Size: Undisclosed
Upfront Cash: Undisclosed
Deal Type: Collaboration
May 30, 2022
Details:
The Hebrew University Portfolio Company addresses modern medicine’s number one problem: extending lifespan without disease and has the potential to improve quality of life for the world’s rapidly growing aging population.
Lead Product(s):
Undisclosed
Therapeutic Area: Neurology
Product Name: Undisclosed
Highest Development Status: Discovery
Product Type: Undisclosed
Partner/Sponsor/Collaborator:
Hebrew University
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
May 23, 2022
Details:
The data to be presented at ASGCT demonstrates the impact that AI has on the discovery and delivery of the next generation of RNA based medicines,fine-tune gene expression, and modulate protein interactions.
Lead Product(s):
RNA-Based Medicine
Therapeutic Area: Neurology
Product Name: Undisclosed
Highest Development Status: Discovery
Product Type: Large molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
May 12, 2022
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