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Find Clinical Drug Development Pipelines & Deals | PipelineProspector

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            Lead Product(s): Dociparstat sodium

            Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: DSTAT

            Highest Development Status: Phase II/ Phase III Product Type: Large molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable February 25, 2021

            Details:

            The primary endpoint of the study is survival without the need for mechanical ventilation through day 28. The first cohort enrolled 12 patients randomized 1:1. One patient on DSTAT was ventilated and recovered.

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            Lead Product(s): Pirfenidone

            Therapeutic Area: Trauma (Emergency, Injury, Surgery) Product Name: Undisclosed

            Highest Development Status: Phase II/ Phase III Product Type: Small molecule

            Partner/Sponsor/Collaborator: Norwest Venture Partners

            Deal Size: $35.5 million Upfront Cash: Undisclosed

            Deal Type: Series B Financing April 27, 2020

            Details:

            Proceeds from the Series B expand the Avalyn's pipeline and will support the launch of a Phase II/III trial of AP01 in chronic lung allograft dysfunction (CLAD).