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The U.S. Family Smoking Prevention and Tobacco Control Act (FSPTCA) defines a Modified Risk Tobacco Product (MRTP) as “any tobacco product that is sold or distributed for use to reduce harm or the risk of tobacco related disease associated with commercially marketed tobacco products” (Family Smoking Prevention and Tobacco Control Act). Regulatory requirements for reduced exposure and modified risk tobacco products are evolving across the globe, and submissions to regulatory authorities are a pa

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