Drugs in Dev.
Cardiology/Vascular Diseases
Discovery

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Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Discovery
Sponsor : REMEDIS
Deal Size : Undisclosed
Deal Type : Collaboration
Life Biosciences Collaborates to Expand Pipeline of Cellular Rejuvenation Therapies
Details : Life Biosciences signed an MOU with REMEDIS to advance its partial epigenetic reprogramming platform for multicentric anti-aging therapies.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
July 22, 2025
Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Discovery
Sponsor : REMEDIS
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Discovery
Sponsor : Bayer AG
Deal Size : $424.0 million
Deal Type : Licensing Agreement
Bayer and Dewpoint Therapeutics sign Licensing Agreement for Heart Disease Program
Details : Bayer obtains global license to develop and commercialize disease-modifying treatment specifically for dilated cardiomyopathy (DCM) patients characterized by specific mutations
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
October 24, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Discovery
Sponsor : Bayer AG
Deal Size : $424.0 million
Deal Type : Licensing Agreement

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Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Discovery
Sponsor : Pfizer Inc
Deal Size : Undisclosed
Deal Type : Partnership
Pfizer Partners with Quotient to Leverage Genetics Against Heart, Renal Diseases
Details : The companies will analyze somatic mutations in diseased patient tissue to inform the discovery and development of potentially transformative therapies for cardiovascular and renal diseases.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
August 28, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Discovery
Sponsor : Pfizer Inc
Deal Size : Undisclosed
Deal Type : Partnership

Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Discovery
Sponsor : Retro Biosciences
Deal Size : $85.0 million
Deal Type : Partnership
Multiply Labs and Retro Biosciences Announce $85 Million Partnership for Cell Therapy
Details : The partnership underscores the versatility of Multiply Labs’ robotic systems for both autologous and allogeneic therapies to advance cell therapy manufacturing for age-related diseases.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
May 14, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Discovery
Sponsor : Retro Biosciences
Deal Size : $85.0 million
Deal Type : Partnership

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Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Discovery
Sponsor : Bayer AG
Deal Size : Undisclosed
Deal Type : Collaboration
Bayer and Evotec Collaborate to Advance Precision Cardiology
Details : The collaboration aims to identify & validate novel targets building a portfolio of precision cardiology therapeutics by leveraging Evotec's disease modeling with human induced pluripotent stem cells.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
April 30, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Discovery
Sponsor : Bayer AG
Deal Size : Undisclosed
Deal Type : Collaboration

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Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Discovery
Sponsor : Biotheus
Deal Size : Undisclosed
Deal Type : Collaboration
Bitterroot and Biotheus Collaborate to Develop Bispecific Proteins in Cardio-Immunology
Details : This collaboration will focus on discovering and developing medicines that may offer new hope for patients suffering from atherosclerosis and other life-threatening cardiovascular conditions.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
February 26, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Discovery
Sponsor : Biotheus
Deal Size : Undisclosed
Deal Type : Collaboration

Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Discovery
Sponsor : Hevolution Foundation
Deal Size : $21.0 million
Deal Type : Funding
Details : The net proceeds from the fundings will be used by Buck Institute to accelerate the discoveries toward therapeutic interventions specifically targeting aging.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
November 30, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Discovery
Sponsor : Hevolution Foundation
Deal Size : $21.0 million
Deal Type : Funding

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Lead Product(s) : ETH51
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Discovery
Sponsor : Heqet Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under the terms of the agreement, Heqet will lead the development of ETH51, RNA-based therapeutics for heart attack and heart failure, while Ethris will provide its proprietary Stabilized NanoParticle (SNaP) LNP platform to deliver ncRNA payloads to the ...
Product Name : Undisclosed
Product Type : Miscellaneous
Upfront Cash : Undisclosed
November 13, 2023
Lead Product(s) : ETH51
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Discovery
Sponsor : Heqet Therapeutics
Deal Size : Undisclosed
Deal Type : Collaboration

Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Discovery
Sponsor : CSL
Deal Size : $0.3 million
Deal Type : Funding
Details : These Global RAI awardees’ research addresses important unmet medical needs in several of CSL’s therapeutic areas, which include immunology, nephrology and transplant, respiratory, hematology, cardiovascular and metabolic disease, and vaccines.
Product Name : Undisclosed
Product Type : Undisclosed
Upfront Cash : Undisclosed
October 04, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Discovery
Sponsor : CSL
Deal Size : $0.3 million
Deal Type : Funding

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Lead Product(s) : LX2021
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Discovery
Sponsor : Sarepta Therapeutics
Deal Size : Undisclosed
Deal Type : Financing
Details : In connection with this investment, the companies will explore the development of novel gene therapy candidates, including LX2021 and LX2022 for a range of cardiovascular diseases.
Product Name : Undisclosed
Product Type : Cell & Gene Therapy
Upfront Cash : Undisclosed
August 28, 2023
Lead Product(s) : LX2021
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Discovery
Sponsor : Sarepta Therapeutics
Deal Size : Undisclosed
Deal Type : Financing
