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    [{"orgOrder":0,"company":"Locate Bio","sponsor":"Mercia Ventures","pharmaFlowCategory":"D","therapeuticArea":"Orthopedics\/Orthopedic Surgery","country":"UNITED KINGDOM","productType":"Protein","year":"2024","type":"Funding","leadProduct":"rhBMP-2","moa":"Activin receptor type-1 | Bone morphogenetic protein receptor type-1A | Activin receptor type-2B | Bone morphogenetic protein receptor type-2 | Bone morphogenetic protein receptor type-1B | Activin receptor type-2A","graph1":"Orthopedics\/Orthopedic Surgery","graph2":"Preclinical","graph3":"Locate Bio","amount2":0.01,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Orthopedics","amount2New":0.01,"dosageForm":"Undisclosed","sponsorNew":"Locate Bio \/ Mercia Ventures","highestDevelopmentStatusID":"4","companyTruncated":"Locate Bio \/ Mercia Ventures"},{"orgOrder":0,"company":"Histogen","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Orthopedics\/Orthopedic Surgery","country":"U.S.A","productType":"Cell & Gene Therapy","year":"2020","type":"Inapplicable","leadProduct":"HST 004","moa":"Undisclosed","graph1":"Orthopedics\/Orthopedic Surgery","graph2":"Preclinical","graph3":"Histogen","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Orthopedics","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Histogen \/ Undisclosed","highestDevelopmentStatusID":"4","companyTruncated":"Histogen \/ Undisclosed"},{"orgOrder":0,"company":"Astellas Pharma","sponsor":"Osaka University","pharmaFlowCategory":"D","therapeuticArea":"Orthopedics\/Orthopedic Surgery","country":"JAPAN","productType":"Undisclosed","year":"2024","type":"Collaboration","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Orthopedics\/Orthopedic Surgery","graph2":"Preclinical","graph3":"Astellas Pharma","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Orthopedics","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Astellas Pharma \/ Osaka University","highestDevelopmentStatusID":"4","companyTruncated":"Astellas Pharma \/ Osaka University"}]

    Find Clinical Drug Development Pipelines & Deals | PipelineProspector

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                            Astellas Pharma

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                            Astellas Pharma

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                            • EDQM
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Orthopedics/Orthopedic Surgery

                            Study Phase : Preclinical

                            Sponsor : Osaka University

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            Astellas And Osaka University Partner on Pluripotent Stem Cell Therapy

                            Details : The collaboration aims to develop innovative pluripotent stem cell-derived cartilage organoid cell therapy for the treatment of intervertebral disc degenerative disease.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Undisclosed

                            July 22, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Orthopedics/Orthopedic Surgery

                            Highest Development Status : Preclinical

                            Sponsor : Osaka University

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            Locate Bio

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                            Locate Bio

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                            Lead Product(s) : rhBMP-2

                            Therapeutic Area : Orthopedics/Orthopedic Surgery

                            Study Phase : Preclinical

                            Sponsor : Mercia Ventures

                            Deal Size : $9.8 million

                            Deal Type : Funding

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                            Locate Bio Raises £9.2 Million for LDGraft Clinical Study

                            Details : LDGraft (rhBMP-2) by Locate Bio is undergoing early clinical trials for treating degenerative disc disease.

                            Product Name : LDGraft

                            Product Type : Protein

                            Upfront Cash : Undisclosed

                            April 29, 2024

                            Lead Product(s) : rhBMP-2

                            Therapeutic Area : Orthopedics/Orthopedic Surgery

                            Highest Development Status : Preclinical

                            Sponsor : Mercia Ventures

                            Deal Size : $9.8 million

                            Deal Type : Funding

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                            03

                            Histogen

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                            Histogen

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                            Lead Product(s) : HST 004

                            Therapeutic Area : Orthopedics/Orthopedic Surgery

                            Study Phase : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Histogen Publishes Preclinical Data on its HST 004 Spinal Disc Program

                            Details : Clinical data from the first three cohorts of the ongoing Phase I dose-escalation trial demonstrating safety of MCY-M11 and feasibility of one-day manufacturing will be shared at the ASCO 2020.

                            Product Name : Undisclosed

                            Product Type : Cell & Gene Therapy

                            Upfront Cash : Inapplicable

                            May 14, 2020

                            Lead Product(s) : HST 004

                            Therapeutic Area : Orthopedics/Orthopedic Surgery

                            Highest Development Status : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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