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    [{"orgOrder":0,"company":"Intelligem Therapeutics Australia Pty Ltd.","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Rheumatology","country":"AUSTRALIA","productType":"Undisclosed","year":"2024","type":"Inapplicable","leadProduct":"IG3018","moa":"Undisclosed","graph1":"Rheumatology","graph2":"Phase I\/ Phase II","graph3":"Intelligem Therapeutics Australia Pty Ltd.","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Rheumatology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Intelligem Therapeutics Australia Pty Ltd. \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Intelligem Therapeutics Australia Pty Ltd. \/ Undisclosed"},{"orgOrder":0,"company":"Urica Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Rheumatology","country":"U.S.A","productType":"Miscellaneous","year":"2023","type":"Inapplicable","leadProduct":"Dontinurad","moa":"URAT1","graph1":"Rheumatology","graph2":"Phase I\/ Phase II","graph3":"Urica Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Rheumatology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Urica Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Urica Therapeutics \/ Undisclosed"},{"orgOrder":0,"company":"Alnylam Pharmaceuticals","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Rheumatology","country":"U.S.A","productType":"Oligonucleotide","year":"2022","type":"Inapplicable","leadProduct":"ALN-XDH","moa":"Xanthine dehydrogenase\/oxidase messenger RNA (XDH mRNA)","graph1":"Rheumatology","graph2":"Phase I\/ Phase II","graph3":"Alnylam Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Rheumatology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Alnylam Pharmaceuticals \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Alnylam Pharmaceuticals \/ Undisclosed"},{"orgOrder":0,"company":"Adaptive Phage Therapeutics","sponsor":"Mayo Clinic","pharmaFlowCategory":"DU","therapeuticArea":"Rheumatology","country":"U.S.A","productType":"Undisclosed","year":"2021","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Rheumatology","graph2":"Phase I\/ Phase II","graph3":"Adaptive Phage Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Rheumatology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Adaptive Phage Therapeutics \/ Mayo Clinic","highestDevelopmentStatusID":"7","companyTruncated":"Adaptive Phage Therapeutics \/ Mayo Clinic"},{"orgOrder":0,"company":"Adaptive Phage Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Rheumatology","country":"U.S.A","productType":"Undisclosed","year":"2022","type":"Inapplicable","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Rheumatology","graph2":"Phase I\/ Phase II","graph3":"Adaptive Phage Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Rheumatology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Adaptive Phage Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"7","companyTruncated":"Adaptive Phage Therapeutics \/ Undisclosed"},{"orgOrder":0,"company":"Genentech","sponsor":"Eric B. Suhler","pharmaFlowCategory":"DU","therapeuticArea":"Rheumatology","country":"U.S.A","productType":"Antibody, Unconjugated","year":"2012","type":"Inapplicable","leadProduct":"Tocilizumab","moa":"Interleukin-6 receptor alpha subunit","graph1":"Rheumatology","graph2":"Phase I\/ Phase II","graph3":"Genentech","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Rheumatology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Genentech \/ Eric B. Suhler","highestDevelopmentStatusID":"7","companyTruncated":"Genentech \/ Eric B. Suhler"}]

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                            01

                            Crystalys Therapeutics

                            U.S.A arrow
                            Bio-Europe Autumn
                            Not Confirmed

                            Crystalys Therapeutics

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                            Bio-Europe Autumn
                            Not Confirmed
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                            Lead Product(s) : Dotinurad,Allopurinol

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Novo Holdings

                            Deal Size : $205.0 million

                            Deal Type : Series A Financing

                            DEALS_DEV arrow-down

                            Novo-Backed Crystalys Debuts With $205M to Tackle Gout

                            Details : The financing round will support the advancement of Phase 3 evaluating, FYU-981 (dotinurad), a next-generation, once daily oral, URAT1 inhibitor for the treatment of gout.

                            Product Name : FYU-981

                            Product Type : Miscellaneous

                            Upfront Cash : Undisclosed

                            September 30, 2025

                            Lead Product(s) : Dotinurad,Allopurinol

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Novo Holdings

                            Deal Size : $205.0 million

                            Deal Type : Series A Financing

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                            02

                            Shanton Pharma

                            China arrow
                            Bio-Europe Autumn
                            Not Confirmed

                            Shanton Pharma

                            China arrow
                            Bio-Europe Autumn
                            Not Confirmed
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                            Lead Product(s) : SAP-001

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            PK and Safety Evaluation Study of SAP-001 in Adult Subjects With Normal and Impaired Renal Function

                            Details : SAP-001 is a drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Gout.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            December 11, 2024

                            Lead Product(s) : SAP-001

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Intelligem Therapeutics Australia Pty Ltd.

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                            Bio-Europe Autumn
                            Not Confirmed

                            Intelligem Therapeutics Australia Pty Ltd.

                            Country arrow
                            Bio-Europe Autumn
                            Not Confirmed
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                            Lead Product(s) : IG3018

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Dose Escalation Study of IG3018 in Subjects With Hyperuricemia With or Without Chronic Kidney Disease

                            Details : IG3018 is a drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Hyperuricemia.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            March 15, 2024

                            Lead Product(s) : IG3018

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Urica Therapeutics

                            U.S.A arrow
                            Bio-Europe Autumn
                            Not Confirmed

                            Urica Therapeutics

                            U.S.A arrow
                            Bio-Europe Autumn
                            Not Confirmed
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                            Lead Product(s) : Dontinurad

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Open Label PK, PD and DDI of Dotinurad and Allopurinol in Gout Patients with Hyperuricemia

                            Details : Dontinurad is a Other Small Molecule drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Gout.

                            Product Name : Undisclosed

                            Product Type : Miscellaneous

                            Upfront Cash : Inapplicable

                            September 28, 2023

                            Lead Product(s) : Dontinurad

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            Sunshine Guojian Pharmaceutical

                            China arrow
                            Bio-Europe Autumn
                            Not Confirmed

                            Sunshine Guojian Pharmaceutical

                            China arrow
                            Bio-Europe Autumn
                            Not Confirmed
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                            Lead Product(s) : Recombinant Anti-IL-1 Humanized Monoclonal Antibody

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Phase Ib/II Study of Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection in Chinese Participan...

                            Details : Recombinant Anti-IL-1 Humanized Monoclonal Antibody is a drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Gout.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            October 20, 2022

                            Lead Product(s) : Recombinant Anti-IL-1 Humanized Monoclonal Antibody

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            GeneScience Pharmaceuticals Co Ltd

                            China arrow
                            Bio-Europe Autumn
                            Not Confirmed

                            GeneScience Pharmaceuticals Co Ltd

                            China arrow
                            Bio-Europe Autumn
                            Not Confirmed
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                            Lead Product(s) : Genakumab

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Huashan Hospital | Hainan General Hospital | Linyi People's Hospital | The Second Affiliated Hospital of Chongqing Medical University | Changhai Hospital | The First Affiliated Hospital with Nanjing Medical University | Shengjing Hospital | Affiliated Hos

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Clinical Study of Genakumab for Injection in Patients With Acute Gout

                            Details : Genakumab is a Antibody drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Gout.

                            Product Name : Undisclosed

                            Product Type : Antibody, Unconjugated

                            Upfront Cash : Inapplicable

                            April 14, 2022

                            Lead Product(s) : Genakumab

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Huashan Hospital | Hainan General Hospital | Linyi People's Hospital | The Second Affiliated Hospital of Chongqing Medical University | Changhai Hospital | The First Affiliated Hospital with Nanjing Medical University | Shengjing Hospital | Affiliated Hos

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Adaptive Phage Therapeutics

                            U.S.A arrow
                            Bio-Europe Autumn
                            Not Confirmed

                            Adaptive Phage Therapeutics

                            U.S.A arrow
                            Bio-Europe Autumn
                            Not Confirmed
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bacteriophage Therapy in First Time Chronic Prosthetic Joint Infections

                            Details : This drug candidate is currently being evaluated in phase I/ phase II clinical studies for the treatment of Arthritis, Infectious.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            March 07, 2022

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Alnylam Pharmaceuticals

                            U.S.A arrow
                            Bio-Europe Autumn
                            Not Confirmed

                            Alnylam Pharmaceuticals

                            U.S.A arrow
                            Bio-Europe Autumn
                            Not Confirmed
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                            Lead Product(s) : ALN-XDH

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study to Evaluate ALN-XDH in Healthy Subjects and Patients With Gout

                            Details : ALN-XDH is a Oligonucleotide drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Gout.

                            Product Name : Undisclosed

                            Product Type : Oligonucleotide

                            Upfront Cash : Inapplicable

                            February 25, 2022

                            Lead Product(s) : ALN-XDH

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Adaptive Phage Therapeutics

                            U.S.A arrow
                            Bio-Europe Autumn
                            Not Confirmed

                            Adaptive Phage Therapeutics

                            U.S.A arrow
                            Bio-Europe Autumn
                            Not Confirmed
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Mayo Clinic

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bacteriophage Therapy in Patients With Prosthetic Joint Infections

                            Details : This drug candidate is currently being evaluated in phase I/ phase II clinical studies for the treatment of Arthritis, Infectious.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            March 08, 2021

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Mayo Clinic

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            InventisBio

                            China arrow
                            Bio-Europe Autumn
                            Not Confirmed

                            InventisBio

                            China arrow
                            Bio-Europe Autumn
                            Not Confirmed
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                            Lead Product(s) : D-0120

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            D-0120 Safety and PK/PD Study in China

                            Details : D-0120 is a drug candidate, which is currently being evaluated in phase I/ phase II clinical studies for the treatment of Hyperuricemia.

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            April 23, 2019

                            Lead Product(s) : D-0120

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Undisclosed

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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