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    [{"orgOrder":0,"company":"Intelligem Therapeutics Australia Pty Ltd.","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Rheumatology","country":"","productType":"Undisclosed","year":"2024","type":"Inapplicable","leadProduct":"IG3018","moa":"||Undisclosed","graph1":"Rheumatology","graph2":"Phase I\/ Phase II","graph3":"Intelligem Therapeutics Australia Pty Ltd.","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Rheumatology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Intelligem Therapeutics Australia Pty Ltd. \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Intelligem Therapeutics Australia Pty Ltd. \/ Inapplicable"},{"orgOrder":0,"company":"Adaptive Phage Therapeutics","sponsor":"Mayo Clinic","pharmaFlowCategory":"DU","therapeuticArea":"Rheumatology","country":"U.S.A","productType":"Undisclosed","year":"2021","type":"Inapplicable","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Rheumatology","graph2":"Phase I\/ Phase II","graph3":"Adaptive Phage Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Rheumatology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Adaptive Phage Therapeutics \/ Mayo Clinic","highestDevelopmentStatusID":"7","companyTruncated":"Adaptive Phage Therapeutics \/ Mayo Clinic"},{"orgOrder":0,"company":"Adaptive Phage Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Rheumatology","country":"U.S.A","productType":"Undisclosed","year":"2022","type":"Inapplicable","leadProduct":"Inapplicable","moa":"||Undisclosed","graph1":"Rheumatology","graph2":"Phase I\/ Phase II","graph3":"Adaptive Phage Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Rheumatology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Adaptive Phage Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Adaptive Phage Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Alnylam Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Rheumatology","country":"U.S.A","productType":"Oligonucleotide","year":"2022","type":"Inapplicable","leadProduct":"ALN-XDH","moa":"||Xanthine dehydrogenase\/oxidase messenger RNA (XDH mRNA)","graph1":"Rheumatology","graph2":"Phase I\/ Phase II","graph3":"Alnylam Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Rheumatology","amount2New":0,"dosageForm":"Injection","sponsorNew":"Alnylam Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Alnylam Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Urica Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Rheumatology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Allopurinol","moa":"||URAT1","graph1":"Rheumatology","graph2":"Phase I\/ Phase II","graph3":"Urica Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Rheumatology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Urica Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"Urica Therapeutics \/ Inapplicable"}]

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                            01

                            Shanton Pharma Pte. Ltd.

                            Country arrow
                            EPSC
                            Not Confirmed

                            Shanton Pharma Pte. Ltd.

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                            EPSC
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                            Lead Product(s) : SAP-001,Inapplicable

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            PK and Safety Evaluation Study of SAP-001 in Adult Subjects With Normal and Impaired Renal Function

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            December 11, 2024

                            Lead Product(s) : SAP-001,Inapplicable

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Intelligem Therapeutics Australia Pty Ltd.

                            Country arrow
                            EPSC
                            Not Confirmed

                            Intelligem Therapeutics Australia Pty Ltd.

                            Country arrow
                            EPSC
                            Not Confirmed
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                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : IG3018,Inapplicable

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Dose Escalation Study of IG3018 in Subjects With Hyperuricemia With or Without Chronic Kidney Disease

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            March 15, 2024

                            Lead Product(s) : IG3018,Inapplicable

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Urica Therapeutics

                            U.S.A arrow
                            EPSC
                            Not Confirmed

                            Urica Therapeutics

                            U.S.A arrow
                            EPSC
                            Not Confirmed
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                            • EDQM
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                            Lead Product(s) : Dontinurad,Dotinurad,Allopurinol

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Open Label PK, PD and DDI of Dotinurad and Allopurinol in Gout Patients with Hyperuricemia

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            September 28, 2023

                            Lead Product(s) : Dontinurad,Dotinurad,Allopurinol

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Sunshine Guojian Pharmaceutical

                            China arrow
                            EPSC
                            Not Confirmed

                            Sunshine Guojian Pharmaceutical

                            China arrow
                            EPSC
                            Not Confirmed
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                            • EDQM
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                            Lead Product(s) : Recombinant Anti-IL-1 Humanized Monoclonal Antibody,Inapplicable

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Phase Ib/II Study of Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection in Chinese Participan...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            October 20, 2022

                            Lead Product(s) : Recombinant Anti-IL-1 Humanized Monoclonal Antibody,Inapplicable

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            GeneScience Pharmaceuticals Co Ltd

                            China arrow
                            EPSC
                            Not Confirmed

                            GeneScience Pharmaceuticals Co Ltd

                            China arrow
                            EPSC
                            Not Confirmed
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                            • EDQM
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                            Lead Product(s) : Genakumab,Inapplicable

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Huashan Hospital | Hainan General Hospital | Linyi People's Hospital | The Second Affiliated Hospital of Chongqing Medical University | Changhai Hospital | The First Affiliated Hospital with Nanjing Medical University | Shengjing Hospital | Affiliated Hos

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Clinical Study of Genakumab for Injection in Patients With Acute Gout

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            April 14, 2022

                            Lead Product(s) : Genakumab,Inapplicable

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Huashan Hospital | Hainan General Hospital | Linyi People's Hospital | The Second Affiliated Hospital of Chongqing Medical University | Changhai Hospital | The First Affiliated Hospital with Nanjing Medical University | Shengjing Hospital | Affiliated Hos

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Adaptive Phage Therapeutics

                            U.S.A arrow
                            EPSC
                            Not Confirmed

                            Adaptive Phage Therapeutics

                            U.S.A arrow
                            EPSC
                            Not Confirmed
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                            Lead Product(s) : Undisclosed,Inapplicable

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bacteriophage Therapy in First Time Chronic Prosthetic Joint Infections

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            March 07, 2022

                            Lead Product(s) : Undisclosed,Inapplicable

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Alnylam Pharmaceuticals

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                            EPSC
                            Not Confirmed

                            Alnylam Pharmaceuticals

                            U.S.A arrow
                            EPSC
                            Not Confirmed
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                            Lead Product(s) : ALN-XDH,Inapplicable

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A Study to Evaluate ALN-XDH in Healthy Subjects and Patients With Gout

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Oligonucleotide

                            Upfront Cash : Inapplicable

                            February 25, 2022

                            Lead Product(s) : ALN-XDH,Inapplicable

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            Adaptive Phage Therapeutics

                            U.S.A arrow
                            EPSC
                            Not Confirmed

                            Adaptive Phage Therapeutics

                            U.S.A arrow
                            EPSC
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Undisclosed,Inapplicable

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Mayo Clinic

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Bacteriophage Therapy in Patients With Prosthetic Joint Infections

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            March 08, 2021

                            Lead Product(s) : Undisclosed,Inapplicable

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Mayo Clinic

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            InventisBio

                            China arrow
                            EPSC
                            Not Confirmed

                            InventisBio

                            China arrow
                            EPSC
                            Not Confirmed
                            • fda
                            • EDQM
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                            Lead Product(s) : D-0120,Inapplicable

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            D-0120 Safety and PK/PD Study in China

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Undisclosed

                            Upfront Cash : Inapplicable

                            April 23, 2019

                            Lead Product(s) : D-0120,Inapplicable

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            AstraZeneca

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                            EPSC
                            Not Confirmed

                            AstraZeneca

                            United Kingdom arrow
                            EPSC
                            Not Confirmed
                            • fda
                            • EDQM
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                            Lead Product(s) : RDEA3170,Febuxostat

                            Therapeutic Area : Rheumatology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Ardea Biosciences

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            A PD/Safety Study of RDEA3170 in Combination With Febuxostat for Treating Gout or Asymptomatic Hyperuricemia P...

                            Details : Undisclosed

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 17, 2014

                            Lead Product(s) : RDEA3170,Febuxostat

                            Therapeutic Area : Rheumatology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Ardea Biosciences

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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