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Details:
ANAVEX®2-73 (blarcamesine) is an orally available, small-molecule activator of the sigma-1 receptor, which, data suggest, is pivotal to restoring neural cell homeostasis and promoting neuroplasticity.
Lead Product(s):
Blarcamesine
Therapeutic Area: Neurology
Product Name: Anavex 2-73
Highest Development Status: Preclinical
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
September 21, 2022
Details:
HT-TBI will be developed as a ready-to-use drug-device combination product for use in non-healthcare settings by patients and caregivers at risk for stroke/TBI, emergency healthcare professionals, and military personnel.
Lead Product(s):
Undisclosed
Therapeutic Area: Neurology
Product Name: HT-TBI
Highest Development Status: Preclinical
Product Type: Undisclosed
Partner/Sponsor/Collaborator:
Altasciences Company Inc
Deal Size: Undisclosed
Upfront Cash: Undisclosed
Deal Type: Partnership
September 20, 2022
Details:
GT-02287, A Brain-penetrant Structurally Targeted Allosteric Regulator of Glucocerebrosidase Shows Evidence of Pharmacological Efficacy in Conduritol β-epoxide (CBE) Models of Parkinson’s Disease.
Lead Product(s):
GT-02287
Therapeutic Area: Neurology
Product Name: GT-02287
Highest Development Status: Preclinical
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Not Applicable
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
September 19, 2022
Details:
Under the Master Collaboration Agreement, QIAGEN will develop and validate a clinical trial assay that will detect a combination of biomarkers discovered by Neuron23 that together predict the responsiveness of Parkinson’s disease patients to a LRRK2 inhibitor.
Lead Product(s):
Undisclosed
Therapeutic Area: Neurology
Product Name: Undisclosed
Highest Development Status: Preclinical
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Qiagen
Deal Size: Undisclosed
Upfront Cash: Undisclosed
Deal Type: Collaboration
September 16, 2022
Details:
Phase 1 of pre-clinical development, clearly demonstrate that many of chosen bio-compounds have potential to exert beneficial effects that mitigate neurological deficits associated with many CNS disorders and mental health conditions.
Lead Product(s):
Psilocybin-based Therapy
Therapeutic Area: Neurology
Product Name: AKO002
Highest Development Status: Preclinical
Product Type: Small molecule
Partner/Sponsor/Collaborator:
Core One Labs
Deal Size: Not Applicable
Upfront Cash: Not Applicable
Deal Type: Not Applicable
September 16, 2022
Details:
The research collaboration will explore the efficacy of Avicanna’s drug candidates including AVCN319302 in animal models for Epilepsy. In addition, the research collaboration will evaluate the anti-seizure properties of rare cannabinoids in isolation and in combination.
Lead Product(s):
AVCN319302,Cannabidiol
Therapeutic Area: Neurology
Product Name: AVCN319302
Highest Development Status: Preclinical
Product Type: Small molecule
Partner/Sponsor/Collaborator:
University of Toronto
Deal Size: Undisclosed
Upfront Cash: Undisclosed
Deal Type: Collaboration
September 15, 2022
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