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                          Top Deals by Deal Size (USD bn)

                          01

                          26th North American ISSX
                          Not Confirmed
                          26th North American ISSX
                          Not Confirmed

                          Lead Product(s) : Somatrogon

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Discovery

                          Partner/Sponsor/Collaborator : HealthCare Royalty

                          Deal Size : $250.0 million

                          Deal Type : Agreement

                          Details : OPKO retained a significant portion of Ngenla (somatrogon) through the agreement. It is an approved product, which is indicated for pediatric patients with growth hormone deficiency.

                          Product Name : Ngenla

                          Product Type : Peptide

                          Upfront Cash : Undisclosed

                          July 17, 2024

                          Lead Product(s) : Somatrogon

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Discovery

                          Partner/Sponsor/Collaborator : HealthCare Royalty

                          Deal Size : $250.0 million

                          Deal Type : Agreement

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                          02

                          26th North American ISSX
                          Not Confirmed
                          26th North American ISSX
                          Not Confirmed

                          Details : Under the collaboration, 5 Prime Sciences will deploy its state-of-the-art human genetics, multi-omics and AI technologies to identify and validate potential drug targets in cardio-metabolic diseases, inc...

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          May 09, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Discovery

                          Partner/Sponsor/Collaborator : Eli Lilly

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          03

                          26th North American ISSX
                          Not Confirmed
                          26th North American ISSX
                          Not Confirmed

                          Details : The collaboration will continue to leverage Sentia’s peptide-based platform and Neurocrine’s drug development expertise in CRF biology to discover novel, long-acting corticotropin-releasing factor rec...

                          Product Name : Undisclosed

                          Product Type : Peptide

                          Upfront Cash : Undisclosed

                          April 16, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Discovery

                          Partner/Sponsor/Collaborator : Neurocrine Biosciences

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          04

                          26th North American ISSX
                          Not Confirmed
                          26th North American ISSX
                          Not Confirmed

                          Details : The partnership aims to improve the manufacturing of Novo's medicines for serious chronic diseases, including diabetes and obesity medications by leveraging Ginkgo's synthetic biology platform from discov...

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          April 10, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Discovery

                          Partner/Sponsor/Collaborator : Novo Nordisk

                          Deal Size : Undisclosed

                          Deal Type : Expanded Collaboration

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                          05

                          26th North American ISSX
                          Not Confirmed
                          26th North American ISSX
                          Not Confirmed

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Discovery

                          Partner/Sponsor/Collaborator : Flanders Innovation & Entrepreneurship

                          Deal Size : $1.7 million

                          Deal Type : Funding

                          Details : The net proceeds will be used to expand Confo’s ongoing R&D efforts in the discovery of next-generation medicines targeting Class B GPCRs using its patent-protected technology platform.

                          Product Name : Undisclosed

                          Product Type : Small molecule

                          Upfront Cash : Undisclosed

                          March 28, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Discovery

                          Partner/Sponsor/Collaborator : Flanders Innovation & Entrepreneurship

                          Deal Size : $1.7 million

                          Deal Type : Funding

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                          06

                          26th North American ISSX
                          Not Confirmed
                          26th North American ISSX
                          Not Confirmed

                          Details : The agreement aims for the development and commercialization of cell therapies derived from iPSCs for the treatment of autoimmune and inflammatory diseases, including type 1 diabetes, multiple sclerosis, ...

                          Product Name : Undisclosed

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          November 09, 2023

                          Lead Product(s) : iPSC-derived Cell Therpay

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Discovery

                          Partner/Sponsor/Collaborator : Century Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          07

                          26th North American ISSX
                          Not Confirmed