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                          Therapeutic Area by Lead Product

                          Study Phase by Lead Product

                          Company by Lead Product

                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : Native Type Ii Collagen

                          Therapeutic Area : Musculoskeletal

                          Study Phase : Undisclosed

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Native Type Ii Collagen is a Protein drug candidate, which is currently being evaluated in clinical studies for the treatment of Arthralgia.

                          Product Name : Undisclosed

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          March 16, 2022

                          Lead Product(s) : Native Type Ii Collagen

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Undisclosed

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Hofseth Biocare ASA

                          Country arrow
                          BioJapan
                          Not Confirmed

                          Hofseth Biocare ASA

                          Country arrow
                          BioJapan
                          Not Confirmed

                          Details : Salmon Undenatured Type II Collagen is a Dietary Supplement drug candidate, which is currently being evaluated in clinical studies for the treatment of Arthralgia.

                          Product Name : Undisclosed

                          Product Type : Dietary Supplement

                          Upfront Cash : Inapplicable

                          August 13, 2025

                          Lead Product(s) : Salmon Undenatured Type II Collagen

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Undisclosed

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          National Taiwan University Hospital

                          Country arrow
                          BioJapan
                          Not Confirmed

                          National Taiwan University Hospital

                          Country arrow
                          BioJapan
                          Not Confirmed

                          Details : Ethanwell Balanced is a Dietary Supplement drug candidate, which is currently being evaluated in clinical studies for the treatment of Sarcopenia.

                          Product Name : Undisclosed

                          Product Type : Dietary Supplement

                          Upfront Cash : Inapplicable

                          August 11, 2025

                          Lead Product(s) : Ethanwell Balanced

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Undisclosed

                          Sponsor : Ethan Nutraceutical Co., Ltd.

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          University of Nottingham

                          Country arrow
                          BioJapan
                          Not Confirmed

                          University of Nottingham

                          Country arrow
                          BioJapan
                          Not Confirmed

                          Details : This drug candidate is currently being evaluated in clinical studies for the treatment of Sarcopenia.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          June 26, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Undisclosed

                          Sponsor : Fresenius Kabi AB Brunna

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Radicle Science

                          Country arrow
                          BioJapan
                          Not Confirmed

                          Radicle Science

                          Country arrow
                          BioJapan
                          Not Confirmed

                          Details : This drug candidate is currently being evaluated in clinical studies for the treatment of Fatigue.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          June 25, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Undisclosed

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          Radicle Science

                          Country arrow
                          BioJapan
                          Not Confirmed

                          Radicle Science

                          Country arrow
                          BioJapan
                          Not Confirmed

                          Details : This drug candidate is currently being evaluated in clinical studies for the treatment of Fatigue.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          June 18, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Undisclosed

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Radicle Science

                          Country arrow
                          BioJapan
                          Not Confirmed

                          Radicle Science

                          Country arrow
                          BioJapan
                          Not Confirmed

                          Details : This drug candidate is currently being evaluated in clinical studies for the treatment of Fatigue.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          May 31, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Undisclosed

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          BioJapan
                          Not Confirmed
                          BioJapan
                          Not Confirmed

                          Details : Native Type Ii Collagen is a Protein drug candidate, which is currently being evaluated in clinical studies for the treatment of Osteoarthritis, Knee.

                          Product Name : Undisclosed

                          Product Type : Protein

                          Upfront Cash : Inapplicable

                          April 08, 2025

                          Lead Product(s) : Native Type Ii Collagen

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Undisclosed

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          National Taiwan Sport University

                          Country arrow
                          BioJapan
                          Not Confirmed

                          National Taiwan Sport University

                          Country arrow
                          BioJapan
                          Not Confirmed

                          Details : Lactobacillus Plantarum GKK1 This is a Probiotic drug candidate, which is currently being evaluated in clinical studies for the treatment of Exercise-Induced Fatigue.

                          Product Name : Undisclosed

                          Product Type : Probiotic

                          Upfront Cash : Inapplicable

                          March 25, 2025

                          Lead Product(s) : Lactobacillus Plantarum GKK1 Probiotic

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Undisclosed

                          Sponsor : Grape King Bio Ltd.

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          BioJapan
                          Not Confirmed
                          BioJapan
                          Not Confirmed

                          Details : Under the licensing agreement, Restoration will gain the rights of cannabinoid-COX-2 conjugate compounds. It is being used for the joint pathology, such as osteoarthritis and rheumatoid arthritis.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          February 04, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Undisclosed

                          Sponsor : Restoration Biologics

                          Deal Size : $61.0 million

                          Deal Type : Licensing Agreement

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