Lead Product(s) : Dotinurad
Therapeutic Area : Rheumatology
Study Phase : Phase I
Sponsor : Fortress Biotech
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Dotinurad, a novel urate transporter (URAT1) inhibitor for gout with potential to address other conditions associated with hyperuricemia such as chronic kidney disease.
Brand Name : Urece
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 29, 2023
Lead Product(s) : Dotinurad
Therapeutic Area : Rheumatology
Highest Development Status : Phase I
Sponsor : Fortress Biotech
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : PRX-115
Therapeutic Area : Rheumatology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : PRX-115 is a PEGylated enzyme expressed via ProCellEx® for intravenous (IV) administration of recombinant Uricase, designed for safe and efficacious treatment of refractory gout
Brand Name : PRX-115
Molecule Type : Large molecule
Upfront Cash : Not Applicable
March 21, 2023
Lead Product(s) : PRX-115
Therapeutic Area : Rheumatology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : HZN-457
Therapeutic Area : Rheumatology
Study Phase : Phase I
Sponsor : Arrowhead Pharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : HZN-457 is a small interfering RNA (siRNA) medicine candidate conjugated to N-acetylgalactosamine (GalNAc) that selectively targets and silences xanthine dehydrogenase expression in the liver, which produces uric acid.
Brand Name : HZN-457
Molecule Type : Large molecule
Upfront Cash : Not Applicable
December 08, 2022
Lead Product(s) : HZN-457
Therapeutic Area : Rheumatology
Highest Development Status : Phase I
Sponsor : Arrowhead Pharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : XB2001
Therapeutic Area : Rheumatology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
FDA Approves XBiotech’s IND in Rheumatology
Details : Natrunix is a new drug, discovered and manufactured at XBiotech’s research and development headquarters in Austin, Texas. The Company believes Natrunix holds promise as a breakthrough therapy for the treatment of inflammatory joint diseases.
Brand Name : Natrunix
Molecule Type : Large molecule
Upfront Cash : Not Applicable
December 13, 2021
Lead Product(s) : XB2001
Therapeutic Area : Rheumatology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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