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              Amzell B.V

              • Development Update

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              NETHERLANDS Netherlands

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              EXTRACTABLES & LEACHABLES SUMMIT

              Participation Not Confirmed

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              Phase 2/3 Trial Suggests that Amzell’s New Topical Treatment (AMZ001) for the Treatment of Knee Osteoarthritis Symptoms Is Effective

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              Lead Product(s): Diclofenac Sodium

              Therapeutic Area: Musculoskeletal Product Name: AMZ001

              Highest Development Status: Phase II/ Phase III Product Type: Small molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable August 14, 2020

              Details:

              This phase 2/3 multi-center, randomized, double-blind trial investigated the effect of a new 3.06% diclofenac sodium gel formulation (AMZ001) for the relief of knee OA pain, in 444 patients exposed to either AMZ001 once daily (QD), AMZ001 twice daily (BID) or placebo.

              Bone Therapeutics

              • Development Update

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              BELGIUM Belgium

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              EXTRACTABLES & LEACHABLES SUMMIT

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              Bone Therapeutics receives Clinical Trial Application (CTA) approval for next clinical studies of its two lead candidates

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              Lead Product(s): Hyaluronic Acid

              Therapeutic Area: Musculoskeletal Product Name: Undisclosed

              Highest Development Status: Phase II/ Phase III Product Type: Small molecule

              Partner/Sponsor/Collaborator: Not Applicable

              Deal Size: Not Applicable Upfront Cash: Not Applicable

              Deal Type: Not Applicable March 23, 2020

              Details:

              Two studies are the pivotal JTA-004 Ph III clinical study targeting osteoarthritic knee pain and Ph IIb study of its allogeneic cell therapy product, ALLOB, in difficult tibial fractures.

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