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Therapeutics","highestDevelopmentStatusID":"11","companyTruncated":"University of Pennsylvania \/ Axsome Therapeutics"},{"orgOrder":0,"company":"Axsome Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Sleep","country":"U.S.A","productType":"Controlled Substance","year":"2021","type":"Inapplicable","leadProduct":"Solriamfetol Hydrochloride","moa":"Sodium-dependent dopamine transporter; Sodium-dependent noradrenaline transporter","graph1":"Sleep","graph2":"Phase IV","graph3":"Axsome Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Sleep","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Axsome Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"11","companyTruncated":"Axsome Therapeutics \/ Undisclosed"},{"orgOrder":0,"company":"Axsome Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Sleep","country":"U.S.A","productType":"Controlled Substance","year":"2024","type":"Inapplicable","leadProduct":"Solriamfetol Hydrochloride","moa":"Sodium-dependent dopamine transporter; Sodium-dependent noradrenaline transporter","graph1":"Sleep","graph2":"Phase IV","graph3":"Axsome Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Sleep","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Axsome Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"11","companyTruncated":"Axsome Therapeutics \/ Undisclosed"},{"orgOrder":0,"company":"Pharmanovia","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Sleep","country":"UNITED KINGDOM","productType":"Miscellaneous","year":"2023","type":"Inapplicable","leadProduct":"Chloral Hydrate","moa":"Undisclosed","graph1":"Sleep","graph2":"Phase IV","graph3":"Pharmanovia","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Sleep","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Pharmanovia \/ Undisclosed","highestDevelopmentStatusID":"11","companyTruncated":"Pharmanovia \/ Undisclosed"},{"orgOrder":0,"company":"Pharmanovia","sponsor":"Lindus Health","pharmaFlowCategory":"DU","therapeuticArea":"Sleep","country":"UNITED KINGDOM","productType":"Miscellaneous","year":"2024","type":"Inapplicable","leadProduct":"Chloral Hydrate","moa":"Undisclosed","graph1":"Sleep","graph2":"Phase IV","graph3":"Pharmanovia","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Sleep","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Pharmanovia \/ Lindus Health","highestDevelopmentStatusID":"11","companyTruncated":"Pharmanovia \/ Lindus Health"},{"orgOrder":0,"company":"Axsome Therapeutics","sponsor":"Undisclosed","pharmaFlowCategory":"DU","therapeuticArea":"Sleep","country":"U.S.A","productType":"Controlled Substance","year":"2022","type":"Inapplicable","leadProduct":"Solriamfetol Hydrochloride","moa":"Undisclosed","graph1":"Sleep","graph2":"Phase IV","graph3":"Axsome Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Sleep","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Axsome Therapeutics \/ Undisclosed","highestDevelopmentStatusID":"11","companyTruncated":"Axsome Therapeutics \/ Undisclosed"},{"orgOrder":0,"company":"Max Zeller Soehne","sponsor":"University of Basel","pharmaFlowCategory":"DU","therapeuticArea":"Sleep","country":"SWITZERLAND","productType":"Plant Extract\/Herbal","year":"2023","type":"Inapplicable","leadProduct":"Valerian-Hop Extract","moa":"Undisclosed","graph1":"Sleep","graph2":"Phase IV","graph3":"Max Zeller Soehne","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Sleep","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Max Zeller Soehne \/ University of Basel","highestDevelopmentStatusID":"11","companyTruncated":"Max Zeller Soehne \/ University of Basel"},{"orgOrder":0,"company":"Forest Laboratories","sponsor":"Mansoor Ahmed M.D.","pharmaFlowCategory":"DU","therapeuticArea":"Sleep","country":"U.S.A","productType":"Miscellaneous","year":"2010","type":"Inapplicable","leadProduct":"Milnacipran","moa":"Norepinephrine transporter","graph1":"Sleep","graph2":"Phase IV","graph3":"Forest Laboratories","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Sleep","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Forest Laboratories \/ Mansoor Ahmed M.D.","highestDevelopmentStatusID":"11","companyTruncated":"Forest Laboratories \/ Mansoor Ahmed M.D."},{"orgOrder":0,"company":"Merck & Co","sponsor":"Burdick, Daniel, M.D.","pharmaFlowCategory":"DU","therapeuticArea":"Sleep","country":"U.S.A","productType":"Miscellaneous","year":"2016","type":"Inapplicable","leadProduct":"Suvorexant","moa":"Orexin receptor","graph1":"Sleep","graph2":"Phase IV","graph3":"Merck & Co","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Sleep","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Merck & Co \/ Burdick, Daniel, M.D.","highestDevelopmentStatusID":"11","companyTruncated":"Merck & Co \/ Burdick, Daniel, M.D."},{"orgOrder":0,"company":"Merz Pharma","sponsor":"Dominik Ettlin","pharmaFlowCategory":"DU","therapeuticArea":"Sleep","country":"GERMANY","productType":"Protein","year":"2021","type":"Inapplicable","leadProduct":"Incobotulinumtoxin A","moa":"SNAP25","graph1":"Sleep","graph2":"Phase IV","graph3":"Merz Pharma","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Sleep","amount2New":0,"dosageForm":"Injection","sponsorNew":"Merz Pharma \/ Dominik Ettlin","highestDevelopmentStatusID":"11","companyTruncated":"Merz Pharma \/ Dominik Ettlin"},{"orgOrder":0,"company":"Axsome Therapeutics","sponsor":"Charles A. Czeisler","pharmaFlowCategory":"DU","therapeuticArea":"Sleep","country":"U.S.A","productType":"Controlled Substance","year":"2021","type":"Inapplicable","leadProduct":"Solriamfetol Hydrochloride","moa":"Sodium-dependent dopamine transporter; Sodium-dependent noradrenaline transporter","graph1":"Sleep","graph2":"Phase IV","graph3":"Axsome Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph IV","therapeuticAreaShortName":"Sleep","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Axsome Therapeutics \/ Charles A. Czeisler","highestDevelopmentStatusID":"11","companyTruncated":"Axsome Therapeutics \/ Charles A. Czeisler"}]

Find Clinical Drug Development Pipelines & Deals | PipelineProspector

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                          Top Deals by Deal Size (USD bn)

                          01

                          Lead Product(s) : Zolpidem Tartrate

                          Therapeutic Area : Sleep

                          Study Phase : Phase IV

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Details : Zolpidem is a Other Small Molecule drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Sleep Wake Disorders.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          April 01, 2010

                          Lead Product(s) : Zolpidem Tartrate

                          Therapeutic Area : Sleep

                          Highest Development Status : Phase IV

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          Sanofi Company Banner

                          02

                          University of Sao Paulo

                          Country arrow
                          AIChE Annual Meeting
                          Not Confirmed

                          University of Sao Paulo

                          Country arrow
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : Eszopiclone is a Other Small Molecule drug candidate, which is currently being evaluated in Phase IV clinical studies for the treatment of Sleep Initiation and Maintenance Disorders.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          June 12, 2025

                          Lead Product(s) : Eszopiclone

                          Therapeutic Area : Sleep

                          Highest Development Status : Phase IV

                          Sponsor : Eurofarma Laboratorios S.A

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          University of California, San Francisco

                          Country arrow
                          AIChE Annual Meeting
                          Not Confirmed

                          University of California, San Francisco

                          Country arrow
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : Lemborexant is a Controlled Substance drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Sleep Disorders, Circadian Rhythm.

                          Product Name : Undisclosed

                          Product Type : Controlled Substance

                          Upfront Cash : Inapplicable

                          March 13, 2025

                          Lead Product(s) : Lemborexant

                          Therapeutic Area : Sleep

                          Highest Development Status : Phase IV

                          Sponsor : Eisai | Stanford University

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : Chloral hydrate is converted rapidly to trichloroethanol, which is largely responsible for its hypnotic action. It is indicated for the treatment for severe insomnia.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          October 01, 2024

                          Lead Product(s) : Chloral Hydrate

                          Therapeutic Area : Sleep

                          Highest Development Status : Phase IV

                          Sponsor : Lindus Health

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : Lemborexant is a Controlled Substance drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Sleep Initiation and Maintenance Disorders.

                          Product Name : Undisclosed

                          Product Type : Controlled Substance

                          Upfront Cash : Inapplicable

                          October 23, 2023

                          Lead Product(s) : Lemborexant

                          Therapeutic Area : Sleep

                          Highest Development Status : Phase IV

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : Chloral Hydrate is a Other Small Molecule drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Sleep Initiation and Maintenance Disorders.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          September 26, 2023

                          Lead Product(s) : Chloral Hydrate

                          Therapeutic Area : Sleep

                          Highest Development Status : Phase IV

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : JZP258 is a drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Idiopathic Hypersomnia.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          May 25, 2023

                          Lead Product(s) : JZP258

                          Therapeutic Area : Sleep

                          Highest Development Status : Phase IV

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : JZP258 is a drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Narcolepsy.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Inapplicable

                          May 22, 2023

                          Lead Product(s) : JZP258

                          Therapeutic Area : Sleep

                          Highest Development Status : Phase IV

                          Sponsor : Undisclosed

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          University of Pennsylvania

                          Country arrow
                          AIChE Annual Meeting
                          Not Confirmed

                          University of Pennsylvania

                          Country arrow
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : Solriamfetol is a Controlled Substance drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Sleep Initiation and Maintenance Disorders.

                          Product Name : Undisclosed

                          Product Type : Controlled Substance

                          Upfront Cash : Inapplicable

                          May 01, 2023

                          Lead Product(s) : Solriamfetol Hydrochloride

                          Therapeutic Area : Sleep

                          Highest Development Status : Phase IV

                          Sponsor : Axsome Therapeutics

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          blank

                          10

                          AIChE Annual Meeting
                          Not Confirmed
                          AIChE Annual Meeting
                          Not Confirmed

                          Details : Suvorexant is a Other Small Molecule drug candidate, which is currently being evaluated in phase IV clinical studies for the treatment of Postoperative Insomnia.

                          Product Name : Undisclosed

                          Product Type : Miscellaneous

                          Upfront Cash : Inapplicable

                          April 21, 2023

                          Lead Product(s) : Suvorexant

                          Therapeutic Area : Sleep

                          Highest Development Status : Phase IV

                          Sponsor : Merck & Co

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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